Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Beatriz Álvarez‐Bernad"'
Autor:
María Ángela Oliva, Carlota Tosat-Bitrián, Lucía Barrado-Gil, Francesca Bonato, Inmaculada Galindo, Urtzi Garaigorta, Beatriz Álvarez-Bernad, Rebeca París-Ogáyar, Daniel Lucena-Agell, Juan Francisco Giménez-Abián, Isabel García-Dorival, Jesús Urquiza, Pablo Gastaminza, José Fernando Díaz, Valle Palomo, Covadonga Alonso
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3448 (2022)
Microtubule targeting agents (MTAs) have been exploited mainly as anti-cancer drugs because of their impact on cellular division and angiogenesis. Additionally, microtubules (MTs) are key structures for intracellular transport, which is frequently hi
Externí odkaz:
https://doaj.org/article/2671d7e2726042098829308ac7b619d1
Autor:
Zlata Boiarska, Helena Pérez‐Peña, Anne‐Catherine Abel, Paola Marzullo, Beatriz Álvarez‐Bernad, Francesca Bonato, Benedetta Santini, Dragos Horvath, Daniel Lucena‐Agell, Francesca Vasile, Maurizio Sironi, J. Fernando Díaz, Andrea E. Prota, Stefano Pieraccini, Daniele Passarella
Publikováno v:
Chemistry – A European Journal. 29
11 p.-7 fig.-4 tab. 7 schem.
Maytansinoids are a successful class of natural and semisynthetic tubulin binders, known for their potent cytotoxic activity. Their wider application as cytotoxins and chemical probes to study tubulin dynamics has be
Maytansinoids are a successful class of natural and semisynthetic tubulin binders, known for their potent cytotoxic activity. Their wider application as cytotoxins and chemical probes to study tubulin dynamics has be
Autor:
Zlata Boiarska, Helena Pérez‐Peña, Anne‐Catherine Abel, Paola Marzullo, Beatriz Álvarez‐Bernad, Francesca Bonato, Benedetta Santini, Dragos Horvath, Daniel Lucena‐Agell, Francesca Vasile, Maurizio Sironi, J. Fernando Díaz, Andrea E. Prota, Stefano Pieraccini, Daniele Passarella
Publikováno v:
Chemistry – A European Journal. 29
Autor:
Juan Estévez-Gallego, Beatriz Álvarez-Bernad, Benet Pera, Christoph Wullschleger, Olivier Raes, Dirk Menche, Juan Carlos Martínez, Daniel Lucena-Agell, Andrea E. Prota, Francesca Bonato, Katja Bargsten, Jelle Cornelus, Juan Francisco Giménez-Abián, Peter Northcote, Michel O. Steinmetz, Shinji Kamimura, Karl-Heinz Altmann, Ian Paterson, Federico Gago, Johan Van der Eycken, J. Fernando Díaz, María Ángela Oliva
Publikováno v:
Structure, 31 (1)
17 p.-5 fig.1 graph. abst.
Taxanes are microtubule-stabilizing agents used in the treatment of many solid tumors, but they often involve side effects affecting the peripheral nervous system. It has been proposed that this could be related to str
Taxanes are microtubule-stabilizing agents used in the treatment of many solid tumors, but they often involve side effects affecting the peripheral nervous system. It has been proposed that this could be related to str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee53e9443e0472be4953641abf09b89
Autor:
Maria Ángela Oliva, Beatriz Álvarez-Bernad, Daniel Lucena-Agell, Marta Martínez Diez, María José Guillén, Gema Santamaría Nuñez, María José Muñoz-Alonso, Eva M. Garrido-Martin, Pablo Avilés, Carmen Cuevas, J. Fernando Díaz
Publikováno v:
Cancer Research. 83:6239-6239
Background: Microtubule targeting compounds are a successful class of anticancer agents in the clinic. Although highly potent, the currently approved antitumor agents targeting tubulin present some drawbacks such as the development of acquired resist
Autor:
Paola Marzullo, Zlata Boiarska, Helena Pérez‐Peña, Anne‐Catherine Abel, Beatriz Álvarez‐Bernad, Daniel Lucena‐Agell, Francesca Vasile, Maurizio Sironi, Karl‐Heinz Altmann, Andrea E. Prota, J. Fernando Díaz, Stefano Pieraccini, Daniele Passarella
Publikováno v:
Chemistry – A European Journal. 28
Autor:
Paola Marzullo, Maurizio Sironi, Daniel Lucena-Agell, J. Fernando Díaz, Daniele Passarella, Helena Pérez-Peña, Zlata Boiarska, Stefano Pieraccini, Beatriz Álvarez-Bernad, Anne-Catherine Abel, Karl-Heinz Altmann, Andrea E. Prota, Francesca Vasile
Publikováno v:
Chemistry – A European Journal
Digital.CSIC. Repositorio Institucional del CSIC
instname
Chemistry-A European Journal, 28 (2)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Chemistry-A European Journal, 28 (2)
Maytansinol is a valuable precursor for the preparation of maytansine derivatives (known as maytansinoids). Inspired by the intriguing structure of the macrocycle and the success in targeted cancer therapy of the derivatives, we explored the maytansi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3462138c4725ef6c10a3c34703000338
http://hdl.handle.net/10261/257058
http://hdl.handle.net/10261/257058