Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Beatrix Schumak"'
Autor:
Julia J. Reichwald, Frederic Risch, Anna-Lena Neumann, Stefan J. Frohberger, Johanna F. Scheunemann, Benjamin Lenz, Alexandra Ehrens, Wiebke Strutz, Beatrix Schumak, Achim Hoerauf, Marc P. Hübner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Group 2 innate lymphoid cells (ILC2s) are inducers of type 2 immune responses, but their role during filarial infection remains unclear. In the present study, we used the Litomosoides sigmodontis rodent model of filariasis to analyze ILC2s during inf
Externí odkaz:
https://doaj.org/article/1acc41176560467e8afe08d122c37d69
Autor:
Johanna F. Scheunemann, Frederic Risch, Julia J. Reichwald, Benjamin Lenz, Anna-Lena Neumann, Stephan Garbe, Stefan J. Frohberger, Marianne Koschel, Jesuthas Ajendra, Maximilian Rothe, Eicke Latz, Christoph Coch, Gunther Hartmann, Beatrix Schumak, Achim Hoerauf, Marc P. Hübner
Publikováno v:
Vaccines, Vol 11, Iss 5, p 966 (2023)
More than two-hundred-million people are infected with filariae worldwide. However, there is no vaccine available that confers long-lasting protection against filarial infections. Previous studies indicated that vaccination with irradiated infective
Externí odkaz:
https://doaj.org/article/b87d9cd8fe334b3eaac4ac43de97300f
Autor:
Johanna F. Scheunemann, Julia J. Reichwald, Patricia Jebett Korir, Janina M. Kuehlwein, Lea-Marie Jenster, Christiane Hammerschmidt-Kamper, Matthew D. Lewis, Katrin Klocke, Max Borsche, Kim E. Schwendt, Camille Soun, Stephanie Thiebes, Andreas Limmer, Daniel R. Engel, Ann-Kristin Mueller, Achim Hoerauf, Marc P. Hübner, Beatrix Schumak
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cerebral malaria is a potentially lethal disease, which is caused by excessive inflammatory responses to Plasmodium parasites. Here we use a newly developed transgenic Plasmodium berghei ANKA (PbAAma1OVA) parasite that can be used to study parasite-s
Externí odkaz:
https://doaj.org/article/d731aa41bf42464ead8cc7486303f906
Autor:
Christoph Coch, Benjamin Hommertgen, Thomas Zillinger, Juliane Daßler-Plenker, Bastian Putschli, Maximilian Nastaly, Beate M. Kümmerer, Johanna F. Scheunemann, Beatrix Schumak, Sabine Specht, Martin Schlee, Winfried Barchet, Achim Hoerauf, Eva Bartok, Gunther Hartmann
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
During blood-stage malaria, the innate immune system initiates the production of pro-inflammatory cytokines, including IFN-γ, that are critical to host defense and responsible for severe disease. Nonetheless, the innate immune pathways activated dur
Externí odkaz:
https://doaj.org/article/02c8566af8ae41498b09c31bd0928bb9
Autor:
Kathy Stein, Mariola Lysson, Beatrix Schumak, Tim Vilz, Sabine Specht, Jürgen Heesemann, Axel Roers, Jörg C. Kalff, Sven Wehner
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Objective: Postoperative ileus (POI) is an inflammation-mediated complication of abdominal surgery, characterized by intestinal dysmotility and leukocyte infiltration into the muscularis externa (ME). Previous studies indicated that interleukin (IL)-
Externí odkaz:
https://doaj.org/article/f5e890cbcdbd43239fa716c4487c007e
Autor:
Kim E Schmidt, Janina M Kuepper, Beatrix Schumak, Judith Alferink, Andrea Hofmann, Shanshan W Howland, Laurent Rénia, Andreas Limmer, Sabine Specht, Achim Hoerauf
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192717 (2018)
Malaria ranks among the most important infectious diseases worldwide and affects mostly people living in tropical countries. Mechanisms involved in disease progression are still not fully understood and specific treatments that might interfere with c
Externí odkaz:
https://doaj.org/article/c26df7e621624b74b955920925eb7e54
Autor:
Florian Wirsdörfer, Jörg M Bangen, Eva Pastille, Daniel Schmitz, Sascha Flohé, Beatrix Schumak, Stefanie B Flohé
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155870 (2016)
Skeletal muscle injury causes a local sterile inflammatory response. In parallel, a state of immunosuppression develops distal to the site of tissue damage. Granulocytes and monocytes that are rapidly recruited to the site of injury contribute to tis
Externí odkaz:
https://doaj.org/article/f9f41d0e1adf4ab19efb5f117389e302
Autor:
Beatrix Schumak, Katrin Klocke, Janina M Kuepper, Aindrila Biswas, Andrea Djie-Maletz, Andreas Limmer, Nico van Rooijen, Matthias Mack, Achim Hoerauf, Ildiko Rita Dunay
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124080 (2015)
Plasmodium berghei ANKA (PbA) infection of C57BL/6 mice leads to experimental cerebral malaria (ECM) that is commonly associated with serious T cell mediated damage. In other parasitic infection models, inflammatory monocytes have been shown to regul
Externí odkaz:
https://doaj.org/article/073d98afaadc4d58a00f3be523fab500
Autor:
Daniela Paulsen, Andreas Urban, Andreas Knorr, Claudia Hirth-Dietrich, Angela Siegling, Hans-Dieter Volk, Andrew A Mercer, Andreas Limmer, Beatrix Schumak, Percy Knolle, Helga Ruebsamen-Schaeff, Olaf Weber
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74605 (2013)
Inactivated orf virus (iORFV), strain D1701, is a potent immune modulator in various animal species. We recently demonstrated that iORFV induces strong antiviral activity in animal models of acute and chronic viral infections. In addition, we found D
Externí odkaz:
https://doaj.org/article/fa712be5788d496f8fefc89646390000
Autor:
Marc Beyer, Beatrix Schumak, Martin R Weihrauch, Bettina Andres, Thomas Giese, Elmar Endl, Percy A Knolle, Sabine Classen, Andreas Limmer, Joachim L Schultze
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30422 (2012)
Regulatory T cells (T(reg) cells) are increased in context of malignancies and their expansion can be correlated with higher disease burden and decreased survival. Initially, interleukin 2 (IL-2) has been used as T-cell growth factor in clinical vacc
Externí odkaz:
https://doaj.org/article/cf07cffb8b024de5b8fa7224cde3b8d7