Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Beatrix Scholz"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 23 (2020)
BACKGROUND Transgenic mice (TG) with heart‐directed overexpresion of the isoform of the transcription factor cyclic adenosine monophosphate response element modulator (CREM), CREM‐IbΔC‐X, display spontaneous atrial fibrillation (AF) and action
Externí odkaz:
https://doaj.org/article/f5c5423e17954e17af07d2791ae9a1ff
Autor:
Frank T. Stümpel, Juliane Stein, Kirsten Himmler, Beatrix Scholz, Matthias D. Seidl, Boris V. Skryabin, Frank U. Müller
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Background: Atrial fibrillation (AF) is a significant cause of morbidity and mortality with foreseeably increasing prevalence. While large animal models of the disease are well established but resource intensive, transgenic AF mouse models are not ye
Externí odkaz:
https://doaj.org/article/bb751c088c94441da8023a0cc5595818
Autor:
Uwe Lendeckel, Kirsten Himmler, Andreas Gardemann, Carmen Wolke, Jan S. Schulte, Edda Fehrmann, Beatrix Scholz, Matthias D. Seidl, F.U. Müller, Eva Wardelmann, Andreas Goette, Alicja Bukowska, M. Felgendreher
Publikováno v:
Thrombosis Research. 163:172-179
The molecular pathomechanisms underlying atrial thrombogenesis are multifactorial and still require detailed investigations. Transgenic mice with cardiomyocyte-directed expression of the transcriptional repressor CREM-IbΔC-X (CREM-TG) represent an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4419aad97b819a9252fa2ca86804dfbb
https://doi.org/10.1016/j.thromres.2017.07.033
https://doi.org/10.1016/j.thromres.2017.07.033
Autor:
Dierk Thomas, Antonius Ratte, Stefan Kallenberger, Gábor Veres, Arjang Ruhparwar, Joachim R. Ehrlich, Ursula Tochtermann, Jan S. Schulte, Maria-Patapia Zafeiriou, Niels Voigt, Constanze Schmidt, Matthias Karck, Felix Wiedmann, Beatrix Scholz, Frank U. Müller, Hugo A. Katus
Publikováno v:
Progress in Biophysics and Molecular Biology. 130:233-243
Two-pore-domain potassium (K 2P ) channels modulate cellular excitability. The significance of stretch-activated cardiac K 2P channels (K 2P 2.1, TREK-1, KCNK 2; K 2P 4.1, TRAAK, KCNK 4; K 2P 10.1, TREK-2, KCNK 10) in heart disease has not been eluci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9fff2e8352b9c837be741c3a8a527a4
https://doi.org/10.1016/j.pbiomolbio.2017.05.004
https://doi.org/10.1016/j.pbiomolbio.2017.05.004
Autor:
Niels Voigt, Constanze Schmidt, Jan S. Schulte, Dierk Thomas, Hugo A. Katus, Antonius Ratte, Bruna Gomes, Franziska S Rathjens, Felix Wiedmann, Frank U. Müller, Edda Fehrmann, Maria-Patapia Zafeiriou, Beatrix Scholz
Publikováno v:
Basic Research in Cardiology. 113
Understanding molecular mechanisms involved in atrial tissue remodeling and arrhythmogenesis in atrial fibrillation (AF) is essential for developing specific therapeutic approaches. Two-pore-domain potassium (K2P) channels modulate cellular excitabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa9f95fcd74a84c4f37ac2228c077b48
https://doi.org/10.1007/s00395-018-0687-9
https://doi.org/10.1007/s00395-018-0687-9
Autor:
Felix, Wiedmann, Jan S, Schulte, Bruna, Gomes, Maria-Patapia, Zafeiriou, Antonius, Ratte, Franziska, Rathjens, Edda, Fehrmann, Beatrix, Scholz, Niels, Voigt, Frank Ulrich, Müller, Dierk, Thomas, Hugo A, Katus, Constanze, Schmidt
Publikováno v:
Basic research in cardiology. 113(4)
Understanding molecular mechanisms involved in atrial tissue remodeling and arrhythmogenesis in atrial fibrillation (AF) is essential for developing specific therapeutic approaches. Two-pore-domain potassium (K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4a21eafdfc76e5d211a2440929abfb1
https://pubmed.ncbi.nlm.nih.gov/29881975
https://pubmed.ncbi.nlm.nih.gov/29881975
Autor:
Frank U. Müller, Anika Witten, Eva Wardelmann, Sabine Hamer, Monika Stoll, Juliane Stein, Andreas Huge, Uwe Völker, Elke Hammer, Matthias D. Seidl, Florentina Pluteanu, Beatrix Scholz
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 10
Background— Reduced expression of genes regulated by the transcription factors CREB/CREM (cAMP response element-binding protein/modulator) is linked to atrial fibrillation (AF) susceptibility in patients. Cardiomyocyte-directed expression of the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98caaeb081bfccb366d866dc9d1d16ef
https://doi.org/10.1161/circep.117.005075
https://doi.org/10.1161/circep.117.005075
Autor:
Constanze, Schmidt, Felix, Wiedmann, Stefan M, Kallenberger, Antonius, Ratte, Jan S, Schulte, Beatrix, Scholz, Frank Ulrich, Müller, Niels, Voigt, Maria-Patapia, Zafeiriou, Joachim R, Ehrlich, Ursula, Tochtermann, Gábor, Veres, Arjang, Ruhparwar, Matthias, Karck, Hugo A, Katus, Dierk, Thomas
Publikováno v:
Progress in biophysics and molecular biology. 130
Two-pore-domain potassium (K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd45540dab3313f42c167fea7dacb644
https://pubmed.ncbi.nlm.nih.gov/28526353
https://pubmed.ncbi.nlm.nih.gov/28526353
Autor:
Matthias D. Seidl, Elke Hammer, Juliane Stein, Florentina Pluteanu, Kirsten Himmler, Uwe Völker, Eva Wardelmann, Beatrix Scholz, Frank U. Müller, Sabine Hamer, Jan S. Schulte
Publikováno v:
Circulation. Arrhythmia and Electrophysiology
Supplemental Digital Content is available in the text.
Background: A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation. In the heart,
Background: A structural, electrical and metabolic atrial remodeling is central in the development of atrial fibrillation (AF) contributing to its initiation and perpetuation. In the heart,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931a50ebc20f3b073eb7a9e6a4757d2b
http://europepmc.org/articles/PMC6426346
http://europepmc.org/articles/PMC6426346
Publikováno v:
Biophysical Journal. 112:545a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc435e437c6ae9b3efbef186206b9002
https://doi.org/10.1016/j.bpj.2016.11.2948
https://doi.org/10.1016/j.bpj.2016.11.2948