Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Beatrix M. Ueberheide"'
Autor:
Jorge L. B. Neves, Cristoval Urcino, Kevin Chase, Cheryl Dowell, Arik J. Hone, David Morgenstern, Victor M. Chua, Iris Bea L. Ramiro, Julita S. Imperial, Lee S. Leavitt, Jasmine Phan, Fernando A. Fisher, Maren Watkins, Shrinivasan Raghuraman, Jortan O. Tun, Beatrix M. Ueberheide, J. Michael McIntosh, Vitor Vasconcelos, Baldomero M. Olivera, Joanna Gajewiak
Publikováno v:
Marine Drugs, Vol 22, Iss 3, p 118 (2024)
The venom of cone snails has been proven to be a rich source of bioactive peptides that target a variety of ion channels and receptors. α-Conotoxins (αCtx) interact with nicotinic acetylcholine receptors (nAChRs) and are powerful tools for investig
Externí odkaz:
https://doaj.org/article/eb10793f322b4e929d26fb3a31f6499e
Autor:
Xuhui Zheng, Gerben Marsman, Keenan A. Lacey, Jessica R. Chapman, Christian Goosmann, Beatrix M. Ueberheide, Victor J. Torres
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The pathogen Staphylococcus aureus releases several pore-forming toxins, termed leukocidins, that kill immune cells. Here, Zheng et al. show that the retention of a leukocidin on bacterial cells and its release are modulated by lipoteichoic acid and
Externí odkaz:
https://doaj.org/article/5b83eef527514fa19ea34ec32cc64ae8
Autor:
Adam J. Pelzek, Bo Shopsin, Emily E. Radke, Kayan Tam, Beatrix M. Ueberheide, David Fenyö, Stuart M. Brown, Qianhao Li, Ada Rubin, Yi Fulmer, William K. Chiang, David N. Hernandez, Hanane El Bannoudi, William E. Sause, Alexis Sommerfield, Isaac P. Thomsen, Andy O. Miller, Victor J. Torres, Gregg J. Silverman
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT Staphylococcus aureus is a Gram-positive opportunistic pathogen that causes superficial and invasive infections in the hospital and community. High mortality from infection emphasizes the need for improved methods for prevention and treatmen
Externí odkaz:
https://doaj.org/article/ffe272ee2a734bd793edf0635cd77c28
Autor:
Miklós Békés, Keiji Okamoto, Sarah B. Crist, Mathew J. Jones, Jessica R. Chapman, Bradley B. Brasher, Francesco D. Melandri, Beatrix M. Ueberheide, Eros Lazzerini Denchi, Tony T. Huang
Publikováno v:
Cell Reports, Vol 5, Iss 3, Pp 826-838 (2013)
The ubiquitin-modification status of proteins in cells is highly dynamic and maintained by specific ligation machineries (E3 ligases) that tag proteins with ubiquitin or by deubiquitinating enzymes (DUBs) that remove the ubiquitin tag. The developmen
Externí odkaz:
https://doaj.org/article/4c428e4f12bb433a823c7305ee785255
Autor:
Sandra Demaria, Silvia C. Formenti, Yasmeen Sarfraz, Karsten A. Pilones, Beatrix M. Ueberheide, Jessica R. Chapman, Nils-Petter Rudqvist, Sheila Spada, Claire Vanpouille-Box, Julie M. Diamond
Proteomics profiles of UT-TEX and RT-TEX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dec2574efeb163d09bf462c47f23188
https://doi.org/10.1158/2326-6066.22539856.v1
https://doi.org/10.1158/2326-6066.22539856.v1
Data from Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs
Autor:
Sandra Demaria, Silvia C. Formenti, Yasmeen Sarfraz, Karsten A. Pilones, Beatrix M. Ueberheide, Jessica R. Chapman, Nils-Petter Rudqvist, Sheila Spada, Claire Vanpouille-Box, Julie M. Diamond
Radiotherapy (RT) used at immunogenic doses leads to accumulation of cytosolic double-stranded DNA (dsDNA) in cancer cells, which activates type I IFN (IFN-I) via the cGAS/STING pathway. Cancer cell–derived IFN-I is required to recruit BATF3-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e499c2643f1879d25a646d3fcca5921
https://doi.org/10.1158/2326-6066.c.6549199.v1
https://doi.org/10.1158/2326-6066.c.6549199.v1
Autor:
Kate E Coleman, Miklós Békés, Jessica R Chapman, Sarah B Crist, Mathew JK Jones, Beatrix M Ueberheide, Tony T Huang
Publikováno v:
eLife, Vol 6 (2017)
NEDD8 is a ubiquitin-like modifier most well-studied for its role in activating the largest family of ubiquitin E3 ligases, the cullin-RING ligases (CRLs). While many non-cullin neddylation substrates have been proposed over the years, validation of
Externí odkaz:
https://doaj.org/article/ad1805509ac84579a8e2fb16bf8f7af8
Autor:
Ann Cavers, Matthias Christian Kugler, Yesim Ozguler, Arshed Fahad Al-Obeidi, Gulen Hatemi, Beatrix M Ueberheide, Didar Ucar, Olivier Manches, Johannes Nowatzky
Publikováno v:
Ann Rheum Dis
ObjectivesThe endoplasmic reticulum aminopeptidase (ERAP1) haplotypeHap10encodes for a variant allotype of the endoplasmic reticulum (ER)-resident peptide-trimming aminopeptidase ERAP1 with low enzymatic activity. This haplotype recessively confers t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1087185499ca98e085e1f42067ba998e
https://europepmc.org/articles/PMC9585993/
https://europepmc.org/articles/PMC9585993/
Publikováno v:
Structure
Bacterial microcompartments (BMCs) are widespread in bacteria and are used for a variety of metabolic purposes, including catabolism of host metabolites. A suite of proteins self-assembles into the shell and cargo layers of BMCs. However, the native
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e234339127806d43caea6ad9a44523
https://doi.org/10.1016/j.str.2022.02.002
https://doi.org/10.1016/j.str.2022.02.002
Publikováno v:
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology, Vol 2010 (2010)
Journal of Biomedicine and Biotechnology, Vol 2010 (2010)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3242731012a09c40fba128ebd19c58
https://doi.org/10.1155/2010/453045
https://doi.org/10.1155/2010/453045