Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Beatrix Kovacs"'
Autor:
Rayyan Gorashi, Nancy Rivera‐Bolanos, Caitlyn Dang, Cedric Chai, Beatrix Kovacs, Sara Alharbi, Syeda Subia Ahmed, Yogesh Goyal, Guillermo Ameer, Bin Jiang
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 6, Pp n/a-n/a (2023)
Abstract Diabetes is a known risk factor for various cardiovascular complications, mediated by endothelial dysfunction. Despite the high prevalence of this metabolic disorder, there is a lack of in vitro models that recapitulate the complexity of gen
Externí odkaz:
https://doaj.org/article/290ef4e9c16a46d9bb3f45750fe17a52
Publikováno v:
Experimental Eye Research. 82:379-388
Muscarinic antagonists, particularly atropine, can inhibit myopia development in several animal models and also in children. However, the biochemical basis of the inhibition of axial eye growth remains obscure, and there are doubts whether muscarinic
Autor:
Beatrix Kovacs, Karoly Gulya
Publikováno v:
Life Sciences. 73:3213-3224
Calmodulin (CaM) mRNAs are expressed with low abundancy in the adult rat neural retina. However, when digoxigenin (DIG)-labeled cRNA probes specific for each CaM mRNA population were hybridized at slightly alkaline pH (pH 8.0), the widespread distrib
Autor:
Shunbin Xu, Caroline E. Haldin, Daniel A. Nicholson, Donald J. Zack, Peter E. Larsen, Karl J. Wahlin, Colleen Cowan, Sanja Turturro, David Valle, Stephen Lumayag, Beatrix Kovacs, P. Dane Witmer, Nicola J. Corbett
Publikováno v:
Lumayag, S, Haldin, C E, Corbett, N J, Wahlin, K J, Cowan, C, Turturro, S, Larsen, P E, Kovacs, B, Witmer, P D, Valle, D, Zack, D J, Nicholson, D A & Xu, S 2013, ' Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration ', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 6, pp. E507-E516 . https://doi.org/10.1073/pnas.1212655110
The microRNA -183/96/182 cluster is highly expressed in the retina and other sensory organs. To uncover its in vivo functions in the retina, we generated a knockout mouse model, designated “ miR-183C GT/GT ,” using a gene-trap embryonic stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e968c4f14eb5929ec9f107749df1f14
https://doi.org/10.1073/pnas.1212655110
https://doi.org/10.1073/pnas.1212655110
Publikováno v:
The Journal of biological chemistry. 282(34)
Although microRNAs (miRNAs) provide a newly recognized level of regulation of gene expression, the miRNA transcriptome of the retina and the contributions of miRNAs to retinal development and function are largely unknown. To begin to understand the f
Autor:
Árpád Csathó, Róbert Járai, Jake W. Jacobs, Beatrix Kovacs-Labadi, David Horvath, Kázmér Karádi, Lynn Nadel, Tamas Makany, János Kállai
Publikováno v:
Behavioral neuroscience. 121(1)
The present article describes the cognitive and emotional aspects of human thigmotaxis (a wall-following spatial strategy) during exploration of virtual and physical spaces. The authors assessed 106 participants with spatial and nonspatial performanc
Publikováno v:
The European journal of neuroscience. 24(7)
Associations formed between conditioned stimuli and drug reward are major contributors in human drug addiction. To better understand the brain changes that accompany this process, we used immunohistochemistry for c-Fos (a neuronal activity marker), s
Publikováno v:
Life sciences. 70(24)
Apparently redundant members of the calmodulin (CaM) gene family encode for the same amino acid sequence. CaM, a ubiquitous cytoplasmic calcium ion receptor, regulates the function of a variety of target molecules even in a single cell. Maintenance o
Autor:
Karoly Gulya, Beatrix Kovacs
Publikováno v:
Brain research. Molecular brain research. 102(1-2)
Calmodulin (CaM) displays complex cytoplasmic and synaptic functions in the nervous system. However, the very little information that is available on the gene expression of the multiple CaM genes in different glial cell types are from brain tissues o
Publikováno v:
Investigative Opthalmology & Visual Science. 52:4402
PURPOSE Diabetic retinopathy (DR) is one of the leading causes of blindness. However, the roles of microRNAs (miRNAs) in DR are still unknown. The aims of this study were to identify miRNAs involved in early DR and to characterize their roles in the