Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Beatrix Bartók"'
Autor:
Yoshiya Tanaka, Tatsuya Atsumi, Daniel Aletaha, Beatrix Bartok, Alena Pechonkina, Ling Han, Kahaku Emoto, Shungo Kano, Vijay Rajendran, Tsutomu Takeuchi
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 1, Pp 161-185 (2022)
Abstract Introduction We conducted a post hoc analysis of efficacy and safety of filgotinib stratified by estimated radiographic progression rate before baseline (BL) in patients with rheumatoid arthritis (RA) who had inadequate response to methotrex
Externí odkaz:
https://doaj.org/article/5ad3c011326f47e39cc3a991b6b2f59f
Autor:
Bernard G. Combe, Yoshiya Tanaka, Maya H. Buch, Peter Nash, Gerd R. Burmester, Alan J. Kivitz, Beatrix Bartok, Alena Pechonkina, Katrina Xia, Kahaku Emoto, Shungo Kano, Thijs K. Hendrikx, Robert B. M. Landewé, Daniel Aletaha
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 1, Pp 53-70 (2022)
Abstract Introduction This exploratory analysis of FINCH 1 (NCT02889796) examined filgotinib (FIL) efficacy and safety in a subgroup of patients with rheumatoid arthritis (RA) and inadequate response to methotrexate (MTX; MTX-IR) who had four poor pr
Externí odkaz:
https://doaj.org/article/d5f278750ece4369b8287f893aae3cee
Autor:
Meredith A. Mathis, Ruedi Aebersold, Amanda Campbell, Philip C. Wrage, Rob Hooft van Huijsduijnen, Nicolai S. C. van Oers, Jennifer A. Young, Beatrix Bartók, Sébastien Wälchli, Julian D. Watts, Lisa A. Pitcher, Margaret S. Sozio
Publikováno v:
Journal of Biological Chemistry. 279:7760-7769
Protein-tyrosine phosphatases (PTPases) play key roles in regulating tyrosine phosphorylation levels in cells, yet the identity of their substrates remains limited. We report here on the identification of PTPases capable of dephosphorylating the phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44479b3dcb35305bb1b48bde382f554
https://doi.org/10.1074/jbc.m309994200
https://doi.org/10.1074/jbc.m309994200
Autor:
Philip C. Wrage, Jennifer A. Young, Meredith A. Mathis, Nicolai S. C. van Oers, Lisa A. Pitcher, Beatrix Bartók
Publikováno v:
Immunological Reviews. 191:47-61
The interaction between the T cell receptor (TCR) and its cognate antigen/major histocompatibility complex (MHC) complex activates a cascade of intracellular protein phosphorylations within the T cell. The signals are initiated by the specific phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7523f28f044063c4bbf5b0fe647312ee
https://doi.org/10.1034/j.1600-065x.2003.00003.x
https://doi.org/10.1034/j.1600-065x.2003.00003.x
Autor:
Bernard G. Combe, Yoshiya Tanaka, Maya H. Buch, Peter Nash, Gerd R. Burmester, Alan J. Kivitz, Beatrix Bartok, Alena Pechonkina, Katrina Xia, Kahaku Emoto, Shungo Kano, Thijs K. Hendrikx, Robert B. M. Landewé, Daniel Aletaha
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 1, Pp 71-72 (2023)
Externí odkaz:
https://doaj.org/article/482e0de723eb4725b687f0331d72bd59
Autor:
Lisa A, Pitcher, Jennifer A, Young, Meredith A, Mathis, Philip C, Wrage, Beatrix, Bartók, Nicolai S C, van Oers
Publikováno v:
Immunological reviews. 191
The interaction between the T cell receptor (TCR) and its cognate antigen/major histocompatibility complex (MHC) complex activates a cascade of intracellular protein phosphorylations within the T cell. The signals are initiated by the specific phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a515602ab56cc991afffeca363457b27
https://pubmed.ncbi.nlm.nih.gov/12614351
https://pubmed.ncbi.nlm.nih.gov/12614351
Autor:
René Westhovens, Thijs Hendrikx, Beatrix Bartok, Cécile Gaujoux-Viala, Giovanni Adami, Zhaoyu Yin, Ying Guo, Osvaldo Daniel Messina, Alan Matsumoto
Publikováno v:
RMD Open, Vol 7, Iss 2 (2021)
Objective This analysis evaluated efficacy and safety of filgotinib, a Janus-associated kinase 1-preferential inhibitor, in methotrexate (MTX)-naive patients with rheumatoid arthritis (RA) with multiple poor prognostic factors (PPFs).Methods This was
Externí odkaz:
https://doaj.org/article/aa1c27018d794d62ac93a88a1736a7d0
Autor:
John W Whitaker, David L Boyle, Beatrix Bartok, Scott T Ball, Steffen Gay, Wei Wang, Gary S Firestein
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124254 (2015)
Identifying novel therapeutic targets for the treatment of disease is challenging. To this end, we developed a genome-wide approach of candidate gene prioritization. We independently collocated sets of genes that were implicated in rheumatoid arthrit
Externí odkaz:
https://doaj.org/article/b794fd9002ac4f4ba1d969942a72426a
Autor:
John W Whitaker, David L Boyle, Beatrix Bartok, Scott T Ball, Steffen Gay, Wei Wang, Gary S Firestein
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136334 (2015)
Externí odkaz:
https://doaj.org/article/0d8f76868510409fb98a362a63b34ab1