Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Beatris Mastelic-Gavillet"'
Autor:
Maria Vono, Beatris Mastelic-Gavillet, Elodie Mohr, Malin Östensson, Josefine Persson, Thorunn A. Olafsdottir, Sylvain Lemeille, David Pejoski, Oliver Hartley, Dennis Christensen, Peter Andersen, Arnaud M. Didierlaurent, Ali M. Harandi, Paul-Henri Lambert, Claire-Anne Siegrist
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionC-type lectin receptor (CLR) agonists emerged as superior inducers of primary B cell responses in early life compared with Toll-like receptor (TLR) agonists, while both types of adjuvants are potent in adults.MethodsHere, we explored the
Externí odkaz:
https://doaj.org/article/09b8465345674f77b4bc4ccc4f8b2f3e
Autor:
Beatris Mastelic-Gavillet, Apostolos Sarivalasis, Leyder Elena Lozano, Sebastien Lofek, Tania Wyss, Ignacio Melero, I. Jolanda M. de Vries, Alexandre Harari, Pedro Romero, Lana Elias Kandalaft, Selena Viganó
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe use of circulating cDC1 to generate anti-cancer vaccines is among the most promising approaches to overcome the limited immunogenicity and clinical efficacy of monocyte-derived DC. However, the recurrent lymphopenia and the reduction of
Externí odkaz:
https://doaj.org/article/5be54e6c692e4311960f34643d9bcf9e
Autor:
Ritaparna Ahmed, Leyder Elena Lozano, Amandine Anastasio, Sebastien Lofek, Beatris Mastelic-Gavillet, Blanca Navarro Rodrigo, Sylvain Nguyen, Florence Dartiguenave, Sonia-Cristina Rodrigues-Dias, Valérie Cesson, Massimo Valério, Beat Roth, Lana Elias Kandalaft, Irina Redchenko, Adrian Vivian Sinton Hill, Alexandre Harari, Pedro Romero, Laurent Derré, Selena Viganó
Publikováno v:
Cancers, Vol 15, Iss 12, p 3114 (2023)
Benign prostate hyperplasia (BPH) is a frequent condition in aging men, which affects life quality, causing principally lower urinary tract symptoms. Epidemiologic studies suggest that BPH may raise the risk of developing prostate cancer (PCa), most
Externí odkaz:
https://doaj.org/article/6da04cb3ad9f47ae8006452d5d072779
Autor:
Beatris Mastelic-Gavillet, Blanca Navarro Rodrigo, Laure Décombaz, Haiping Wang, Giuseppe Ercolano, Rita Ahmed, Leyder Elena Lozano, Angela Ianaro, Laurent Derré, Massimo Valerio, Thomas Tawadros, Patrice Jichlinski, Tu Nguyen-Ngoc, Daniel E. Speiser, Grégory Verdeil, Nicolas Gestermann, Olivier Dormond, Lana Kandalaft, George Coukos, Camilla Jandus, Christine Ménétrier-Caux, Christophe Caux, Ping-Chih Ho, Pedro Romero, Alexandre Harari, Selena Vigano
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background Several mechanisms are present in the tumor microenvironment (TME) to impair cytotoxic T cell responses potentially able to control tumor growth. Among these, the accumulation of adenosine (Ado) contributes to tumor progression an
Externí odkaz:
https://doaj.org/article/c904191ffb374b3197b764ab27b445ac
Autor:
Floriane Auderset, Elodie Belnoue, Beatris Mastelic-Gavillet, Paul-Henri Lambert, Claire-Anne Siegrist
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Novel adjuvants, such as Toll-like receptors (TLRs) agonists, are needed for the development of new formulations able to circumvent limitations of current vaccines. Among TLRs, TLR7/8 agonists represent promising candidates, as they are well describe
Externí odkaz:
https://doaj.org/article/7af591375e2849ba84d744b2876ec670
Autor:
Maria Vono, Christiane Sigrid Eberhardt, Floriane Auderset, Beatris Mastelic-Gavillet, Sylvain Lemeille, Dennis Christensen, Peter Andersen, Paul-Henri Lambert, Claire-Anne Siegrist
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1773-1784.e5 (2019)
Summary: Maternal antibodies (MatAbs) protect offspring from infections but limit their responses to vaccination. The mechanisms of this inhibition are still debated. Using murine early-life immunization models mimicking the condition prevailing in h
Externí odkaz:
https://doaj.org/article/d32664b619aa42518f4d409f0cbfc5c0
Autor:
Beatris Mastelic-Gavillet, Maria Vono, Patrícia Gonzalez-Dias, Frederico Moraes Ferreira, Lucas Cardozo, Paul-Henri Lambert, Helder I. Nakaya, Claire-Anne Siegrist
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
T follicular helper (Tfh) cells have emerged as a critical limiting factor for controlling the magnitude of neonatal germinal center (GC) reactions and primary vaccine antibody responses. We compared the functional attributes of neonatal and adult Tf
Externí odkaz:
https://doaj.org/article/09d1a01bbc32422b8cc6a9942fa6e1fb
Autor:
Floriane Auderset, Marie Ballester, Beatris Mastelic-Gavillet, Paola Fontannaz, Martine Chabaud-Riou, Nathalie Reveneau, Marie Garinot, Noëlle Mistretta, Yuanqing Liu, Paul-Henri Lambert, Martina Ochs, Claire-Anne Siegrist
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Pertussis is still observed in many countries despite of high vaccine coverage. Acellular pertussis (aP) vaccination is widely implemented in many countries as primary series in infants and as boosters in school-entry/adolescents/adults (including pr
Externí odkaz:
https://doaj.org/article/cd03835ead6f409fb839b93787ad1851
Autor:
Beatris Mastelic-Gavillet, Klara Balint, Caroline Boudousquie, Philippe O. Gannon, Lana E. Kandalaft
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
With the advent of combined immunotherapies, personalized dendritic cell (DC)-based vaccination could integrate the current standard of care for the treatment of a large variety of tumors. Due to their proficiency at antigen presentation, DC are key
Externí odkaz:
https://doaj.org/article/375cb21308874d069b2b572493f57be0
Autor:
Maria Vono, Christiane Sigrid Eberhardt, Elodie Mohr, Floriane Auderset, Dennis Christensen, Mirco Schmolke, Rhea Coler, Andreas Meinke, Peter Andersen, Paul-Henri Lambert, Beatris Mastelic-Gavillet, Claire-Anne Siegrist
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Neonates and infants are more vulnerable to infections and show reduced responses to vaccination. Consequently, repeated immunizations are required to induce protection and early life vaccines against major pathogens such as influenza are yet unavail
Externí odkaz:
https://doaj.org/article/9dd60d8b944f435ba82923ea937309da