Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Beatrijs I. Valk"'
Autor:
Dario Lehoux, Megan McGrath, Brad Zerler, Douglas E. Raines, Beatrijs I. Valk, John J. A. Marota
Publikováno v:
Anesthesiology, 131(2), 287-304. LIPPINCOTT WILLIAMS & WILKINS
Editor's PerspectiveWhat We Already Know about This Topic The investigational etomidate analog ABP-700 causes involuntary muscle movements in humans at anesthetic doses and seizures in dogs at 10-fold higher toxicologic doses The mechanism of seizure
Autor:
Beatrijs I. Valk, Michel Struys
Publikováno v:
CLINICAL PHARMACOKINETICS
Clinical Pharmacokinetics
Clinical Pharmacokinetics
Etomidate is a hypnotic agent that is used for the induction of anesthesia. It produces its effect by acting as a positive allosteric modulator on the gamma-aminobutyric acid type A receptor and thus enhancing the effect of the inhibitory neurotransm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ed5fafef2721a3bee9e24160e871bb
https://biblio.ugent.be/publication/8722316
https://biblio.ugent.be/publication/8722316
Autor:
Steven Sweeney, Michel Struys, Sascha Meier, Kai van Amsterdam, Izaak den Daas, Anthony Absalom, Peter Meyer, Beatrijs I Valk, Douglas J. Eleveld, Jason Campagna
Publikováno v:
Anesthesiology, 134(1), 35-51. LIPPINCOTT WILLIAMS & WILKINS
Backgroundγ-Aminobutyric acid type A (GABAA) receptor agonists are known to cause involuntary muscle movements. The mechanism of these movements is not known, and its relationship to depth of anesthesia monitoring is unclear. We have explored the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8aed2d26fa55ddc3b104c3ca37038e5
https://research.rug.nl/en/publications/0e2828ea-da69-44ae-bb9d-b5c557f35cf1
https://research.rug.nl/en/publications/0e2828ea-da69-44ae-bb9d-b5c557f35cf1
Autor:
Steven Sweeney, Michel Struys, Kai van Amsterdam, Beatrijs I Valk, Sascha Meier, Izaak den Daas, Jason Campagna, Anthony Absalom, Peter Meyer, Thomas Chou, Douglas J. Eleveld
Publikováno v:
Anesthesiology, 127(1), 20-35. LIPPINCOTT WILLIAMS & WILKINS
Background Cyclopropyl-methoxycarbonylmetomidate (ABP-700) is a new “soft” etomidate analog. The primary objectives of this first-in-human study were to describe the safety and efficacy of ABP-700 and to determine its maximum tolerated dose. Seco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057a34fb46a7f8dfcc78bf9fb97c50ec
https://research.rug.nl/en/publications/98e48bd7-f031-4b51-8e89-41114fcd17e2
https://research.rug.nl/en/publications/98e48bd7-f031-4b51-8e89-41114fcd17e2