Výsledky vyhledávání - "Beatrice Sommer"

Use of the variplex™ SARS-CoV-2 RT-LAMP as a rapid molecular assay to complement RT-PCR for COVID-19 diagnosis

Autor: Birgit Edel, Andreas Henke, Renate Egerer, Beatrice Sommer-Schmid, Jürgen Rödel, Bettina Löffler, Aynur Suleyman, Michael Baier

Publikováno v: Journal of Clinical Virology

Highlights • Rapid detection of SARS-CoV-2 by variplex™ RT-LAMP from respiratory samples. • Homogenization of samples using SL solution for testing without RNA elution. • Combination of RT-LAMP and RT-PCR increases diagnostic accuracy.
B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9477e3b23b72dad7f2e10af40fafa9
http://europepmc.org/articles/PMC7457909

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Phenotypic Effects of Biglycan Deficiency Are Linked to Collagen Fibril Abnormalities, Are Synergized by Decorin Deficiency, and Mimic Ehlers‐Danlos‐Like Changes in Bone and Other Connective Tissues

Autor: Mahesh H. Mankani, I. Eichstetter, P. Gehron Robey, Paolo Bianco, T. Xu, Renato V. Iozzo, A. Corsi, Beatrice Sommer, Alan Boyde, Marian F. Young, J. Liang, Xiao Dong Chen

Publikováno v: Scopus-Elsevier

Decorin (dcn) and biglycan (bgn), two members of the family of small leucine-rich proteoglycans (SLRPs), are the predominant proteoglycans expressed in skin and bone, respectively. Targeted disruption of the dcn gene results in skin laxity and fragil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6474f56e4a60bb3bb2e2b39d8e720cb2
https://doi.org/10.1359/jbmr.2002.17.7.1180

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Transcriptional regulation restricting bone sialoprotein gene expression to both hypertrophic chondrocytes and osteoblasts

Autor: Louis C. Gerstenfeld, Marian F. Young, Thomas Della Torre, Beatrice Sommer, George L. Barnes

Publikováno v: Journal of Cellular Biochemistry. 87:458-469

This study identifies a cis-acting element that confers tissue-restricted expression to the bone sialoprotein (BSP) gene. Using both gain of function and loss-of function studies, we demonstrate that this element acts as a tissue specific enhancer of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf9e1c26b858ed9abd9e762c5db31c3
https://doi.org/10.1002/jcb.10351

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Differential display of human marrow stromal cells reveals unique mRNA expression patterns in response to dexamethasone

Autor: Marian F. Young, Suzanne C Dieudonne, Tian Shun Xu, Anna R. Derubeis, Pamela Gehron Robey, In San Kim, Sergei A. Kuznetsov, Janet M. Kerr, Beatrice Sommer

Publikováno v: Journal of Cellular Biochemistry, 76, 231-243
Journal of Cellular Biochemistry, 76, pp. 231-243

Human bone marrow stromal cells (hBMSC) are pluripotent cells that have the ability to differentiate into bone, cartilage, hematopoietic-supportive stroma, and adipocytes in a process modulated by dexamethasone (DEX). To characterize changes in hBMSC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fc8e338c27d333e58b7fca4e50ea9f
http://hdl.handle.net/2066/265586

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Efficient gene transfer into normal human skeletal cells using recombinant adenovirus and conjugated adenovirus-DNA complexes

Autor: Pamela Gehron Robey, Beatrice Sommer, R. J. Cristiano, M. F. Young, Brian O'Connell, Sergei A. Kuznetsov

Publikováno v: Calcified tissue international. 64(1)

In order to assess efficient DNA gene transfer into human primary cell cultures derived from the skeleton we tested two viral-based procedures. First, replication-deficient recombinant adenoviruses (ADV) were used to infect post-confluent human marro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4914a007a804f759c91c42a8429f6fc0
https://pubmed.ncbi.nlm.nih.gov/9868283

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