Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Beatrice Setnik"'
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 1, Pp 158-171 (2022)
Abstract Chronic antihypertensive treatment often includes combination of two or more therapies with complementary mechanism of action targeting different blood pressure (BP) control system. If available, these components are recommended to be admini
Externí odkaz:
https://doaj.org/article/01aeca5cff574e07b9bc6d15176b77c4
Autor:
Beatrice Setnik, Veeraindar Goli, Naama Levy-Cooperman, Catherine Mills, Megan Shram, Ira Smith
Publikováno v:
Pain Research and Management, Vol 18, Iss 4, Pp e55-e62 (2013)
OBJECTIVE: To evaluate the pharmacodynamic (PD) effects of morphine sulfate and naltrexone hydrochloride extended-release (MSN) capsules compared with controlled-release morphine sulfate (MS) and placebo when crushed and administered intranasally.
Externí odkaz:
https://doaj.org/article/21014173a3914b4da56df0a908c7dc6e
Autor:
Margaret Moline, Shoji Asakura, Carsten Beuckman, Ishani Landry, Beatrice Setnik, Judy Ashworth, Jack E. Henningfield
Publikováno v:
Psychopharmacology. 240:699-711
Rationale Lemborexant (LEM) is a dual orexin receptor antagonist (DORA) approved in multiple countries including the USA, Japan, Canada, Australia, and several Asian countries for the treatment of insomnia in adults. As a compound with central nervou
Autor:
Ishani, Landry, Nancy, Hall, Jagadeesh, Alur, Gleb, Filippov, Larisa, Reyderman, Beatrice, Setnik, Jack, Henningfield, Margaret, Moline
Publikováno v:
Journal of Clinical Psychopharmacology. 42:374-382
As part of a human abuse potential (HAP) study of lemborexant (LEM), the effects of therapeutic (LEM 10 mg), and supratherapeutic doses of LEM 20 mg and LEM 30 mg on cognition and psychomotor performance were compared with placebo (PBO) and suprather
Autor:
Ishani Landry, Nancy Hall, Jagadeesh Aluri, Gleb Filippov, Beatrice Setnik, Satish Dayal, Larisa Reyderman, Margaret Moline
Publikováno v:
Journal of Psychopharmacology. 36:745-755
Background: Lemborexant is a dual orexin receptor antagonist approved to treat insomnia in adults in several countries including the USA, Canada, and Japan. Aims: This study was conducted to investigate effects of lemborexant and alcohol coadministra
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 15, Iss 1, Pp 158-171 (2022)
Clinical and Translational Science, Vol 15, Iss 1, Pp 158-171 (2022)
Chronic antihypertensive treatment often includes combination of two or more therapies with complementary mechanism of action targeting different blood pressure (BP) control system. If available, these components are recommended to be administered as
Autor:
Catherine Munera, Eugene R. Viscusi, Beatrice Setnik, Joseph W. Stauffer, Sukirti N. Bagal, Marc C. Torjman
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 5, Pp 1886-1893 (2021)
Clinical and Translational Science, Vol 14, Iss 5, Pp 1886-1893 (2021)
Difelikefalin, a selective kappa opioid receptor agonist designed to limit central nervous system (CNS) penetration, is under development for the treatment of pruritus. Its hydrophilic, small‐peptidic structure limits CNS entry, minimizing potentia
Autor:
Ishani Landry, Nancy Hall, Jagadeesh Aluri, Gleb Filippov, Larisa Reyderman, Beatrice Setnik, Jack Henningfield, Margaret Moline
Publikováno v:
Journal of clinical psychopharmacology. 42(4)
Lemborexant (LEM) is a dual orexin receptor antagonist approved for the treatment of insomnia in adults in multiple countries including the the United States, Japan, Canada, Australia and several Asian countries.This was a randomized, single-dose, si
Autor:
Catherine Mills, Nancy Chen, Beatrice Setnik, Cynthia Bartlett, Naama Levy-Cooperman, Sian Ratcliffe, Kerri A. Schoedel, Megan J. Shram, Edward M. Sellers
Publikováno v:
Journal of Clinical Psychopharmacology. 40:568-578
Background Human abuse potential studies include multiple measures to assess the subjective effects of central nervous system-active drugs. In this retrospective analysis, measurement properties of commonly used measures were assessed, and factor ana
Publikováno v:
Journal of Opioid Management. 15:507-520
Objective: To identify key characteristics and habits of recreational opioid users. Design: The data were compiled from volunteers who participated in clinical studies at a contract research organization in Toronto, Ontario, Canada. Interventions: Da