Transcriptome Profile During Rabies Virus Infection: Identification of Human CXCL16 as a Potential New Viral Target

Autor: Lena Feige, Inés Sáenz-de-Santa-María, Beatrice Regnault, Rachel Lavenir, Anthony Lepelletier, Ala Halacu, Randrianasolo Rajerison, Sylvie Diop, Chhor Nareth, Jean-Marc Reynes, Philippe Buchy, Hervé Bourhy, Laurent Dacheux

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Rabies virus (RABV), the causative agent for rabies disease is still presenting a major public health concern causing approximately 60,000 deaths annually. This neurotropic virus (genus Lyssavirus, family Rhabdoviridae) induces an acute and almost al

Externí odkaz: https://doaj.org/article/b4836304068a48d095d90d44b84819d8

Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders.

Autor: Claire S Leblond, Jutta Heinrich, Richard Delorme, Christian Proepper, Catalina Betancur, Guillaume Huguet, Marina Konyukh, Pauline Chaste, Elodie Ey, Maria Rastam, Henrik Anckarsäter, Gudrun Nygren, I Carina Gillberg, Jonas Melke, Roberto Toro, Beatrice Regnault, Fabien Fauchereau, Oriane Mercati, Nathalie Lemière, David Skuse, Martin Poot, Richard Holt, Anthony P Monaco, Irma Järvelä, Katri Kantojärvi, Raija Vanhala, Sarah Curran, David A Collier, Patrick Bolton, Andreas Chiocchetti, Sabine M Klauck, Fritz Poustka, Christine M Freitag, Regina Waltes, Marnie Kopp, Eftichia Duketis, Elena Bacchelli, Fiorella Minopoli, Liliana Ruta, Agatino Battaglia, Luigi Mazzone, Elena Maestrini, Ana F Sequeira, Barbara Oliveira, Astrid Vicente, Guiomar Oliveira, Dalila Pinto, Stephen W Scherer, Diana Zelenika, Marc Delepine, Mark Lathrop, Dominique Bonneau, Vincent Guinchat, Françoise Devillard, Brigitte Assouline, Marie-Christine Mouren, Marion Leboyer, Christopher Gillberg, Tobias M Boeckers, Thomas Bourgeron

Publikováno v: PLoS Genetics, Vol 8, Iss 2, p e1002521 (2012)

Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders with a complex inheritance pattern. While many rare variants in synaptic proteins have been identified in patients with ASD, little is known about their effects

Externí odkaz: https://doaj.org/article/03767000fd224a4884ce09193bcfd6c7

Circovirus Hepatitis in Immunocompromised Patient, Switzerland

Autor: Baptiste Hamelin, Philippe Pérot, Ian Pichler, Jasmin D. Haslbauer, David Hardy, David Hing, Sarra Loulizi, Béatrice Regnault, Anouk Pieters, Ingmar Heijnen, Caroline Berkemeier, Maria Mancuso, Verena Kufner, Niels Willi, Anne Jamet, Nolwenn Dheilly, Marc Eloit, Mike Recher, Michael Huber, Kirsten D. Mertz

Publikováno v: Emerging Infectious Diseases, Vol 30, Iss 10, Pp 2140-2144 (2024)

We identified a novel human circovirus in an immunocompromised 66-year-old woman with sudden onset of self-limiting hepatitis. We detected human circovirus 1 (HCirV-1) transcripts in hepatocytes and the HCirV-1 genome long-term in the patient’s blo

Externí odkaz: https://doaj.org/article/7fcfbcfde36f46d884d5553878a03476

Circovirus Hepatitis Infection in Heart-Lung Transplant Patient, France

Autor: Philippe Pérot, Jacques Fourgeaud, Claire Rouzaud, Béatrice Regnault, Nicolas Da Rocha, Hélène Fontaine, Jérôme Le Pavec, Samuel Dolidon, Margaux Garzaro, Delphine Chrétien, Guillaume Morcrette, Thierry Jo Molina, Agnès Ferroni, Marianne Leruez-Ville, Olivier Lortholary, Anne Jamet, Marc Eloit

Publikováno v: Emerging Infectious Diseases, Vol 29, Iss 2, Pp 286-293 (2023)

In March 2022, a 61-year-old woman in France who had received a heart-lung transplant sought treatment with chronic hepatitis mainly characterized by increased liver enzymes. After ruling out common etiologies, we used metagenomic next-generation seq

Externí odkaz: https://doaj.org/article/2173309472bd4b91b55fb8f797487f24

MicroRNA expression profile in human macrophages in response to Leishmania major infection

Autor: Elena Kutumova, Florian Noguier, Kais Ghedira, Oliver Hofmann, ROMAN BRUNO, Ilya Kiselev, Dhafer Laouini, Hanene Attia, Ralf Herwig, Ruy Jauregui, Winston Hide, Ruslan Sharipov, Christoph Wierling, Fabien Pierrat, Beatrice REGNAULT, Pierre-André Cazenave, Fedor Kolpakov, Slimane Ben miled, Sayda Abid, Nicki Tiffin, Razif Gabdoulline, Imen RABHI, David Piquemal, Fatma Zahra Guerfali

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 7, Iss 10, p e2478 (2013)
PLoS Neglected Tropical Diseases, Public Library of Science, 2013, 7 (10), pp.e2478. ⟨10.1371/journal.pntd.0002478⟩
Lemaire, J, Mkannez, G, Guerfali, F Z, Gustin, C, Attia, H, Sghaier, R M, Dellagi, K, Laouini, D, Renard, P & Sysco Consortium 2013, ' MicroRNA Expression Profile in Human Macrophages in Response to Leishmania major Infection ', PLoS neglected tropical diseases, vol. 7, no. 10, pp. e2478 . https://doi.org/10.1371/journal.pntd.0002478

Background Leishmania (L.) are intracellular protozoan parasites able to survive and replicate in the hostile phagolysosomal environment of infected macrophages. They cause leishmaniasis, a heterogeneous group of worldwide-distributed affections, rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a6f876830e7f10c7e2b52cb6fab8c5
https://pubmed.ncbi.nlm.nih.gov/24098824