Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Beatrice Purghè"'
Autor:
Suresh Velnati, Sara Centonze, Giulia Rossino, Beatrice Purghè, Annamaria Antona, Luisa Racca, Sabrina Mula, Elisa Ruffo, Valeria Malacarne, Mario Malerba, Marcello Manfredi, Andrea Graziani, Gianluca Baldanzi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPhosphorylation of diacylglycerol by diacylglycerol-kinases represents a major inhibitory event constraining T cell activation upon antigen engagement. Efficient TCR signalling requires the inhibition of the alpha isoform of diacylglycerol
Externí odkaz:
https://doaj.org/article/d7c6301456144c649c298c8248baa1ae
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112270- (2021)
Exosomes are nano-sized vesicles released by almost all cell types, with a central role as mediators of intercellular communication. In addition to physiological conditions, these extracellular vesicles seem to play a pivotal role in inflammatory pro
Externí odkaz:
https://doaj.org/article/43516ec509014b208004a5cacc5922f6
Autor:
Roberta Fusco, Rosanna Di Paola, Marta Serafini, Tracey Pirali, Salvatore Cuzzocrea, Silvio Aprile, Celia Cordero-Sanchez, Beatrice Purghè, Armando A. Genazzani, Irene Preet Bhela, Beatrice Riva
Publikováno v:
Journal of Medicinal Chemistry
Store-operated calcium entry (SOCE) is important in the maintenance of calcium homeostasis and alterations in this mechanism are responsible for several pathological conditions, including acute pancreatitis. Since the discovery of SOCE, many inhibito
Publikováno v:
Chemical Research in Toxicology. 33:955-966
Despite the isolation of hundreds of bioactive isocyanides from terrestrial fungi and bacteria as well as marine organisms, the isocyanide functionality has so far received little attention from a medicinal chemistry standpoint. The widespread tenet
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss, Pp 112270-(2021)
Exosomes are nano-sized vesicles released by almost all cell types, with a central role as mediators of intercellular communication. In addition to physiological conditions, these extracellular vesicles seem to play a pivotal role in inflammatory pro
Autor:
Arianna Esposito Verza, Riccardo Miggiano, Fabrizio Lombardo, Carmine Fiorillo, Bruno Arcà, Beatrice Purghé, Erika Del Grosso, Ubaldina Galli, Menico Rizzi, Franca Rossi
Publikováno v:
Current Research in Structural Biology, Vol 4, Iss , Pp 246-255 (2022)
The temporary or permanent chemical modification of biomolecules is a crucial aspect in the physiology of all living species. However, while some modules are well characterised also in insects, others did not receive the same attention. This holds tr
Externí odkaz:
https://doaj.org/article/612717f95e7641e588e678c52fe124bc