Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Beatrice Ondondo"'
Autor:
Beatrice Ondondo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/43071503b64446f3ac7259847236e8d3
Autor:
Awen M. Gallimore, Andrew J. Godkin, Ann Ager, David A. Price, David Withers, Katherine K. Wynn, Kristin Ladell, Scott Cutting, Beatrice Ondondo, Sarah N. Lauder, Hayley Bridgeman, Kathryn Smart, Emma Jones, James P. Hindley
PDF file - 234K, S Figure 1 - Levels of Foxp3+ Tregs and T cell activation following various doses of DT treatment. S Figure 2 - Efficient depletion of Foxp3+ Tregs leads to T cell activation and proliferation. S Figure 3 - T cell accumulation in tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ff76f34f1a157e7f043f35839ba7dd
https://doi.org/10.1158/0008-5472.22394828
https://doi.org/10.1158/0008-5472.22394828
Increased Valency of Conserved-mosaic Vaccines Enhances the Breadth and Depth of Epitope Recognition
Autor:
Tomáš Hanke, Andy Gardner, Bette T. Korber, Beatrice Ondondo, Tim Elliott, Sultan Abdul-Jawad, Andy van Hateren
Publikováno v:
Molecular Therapy. 24(2):375-384
The biggest roadblock in development of effective vaccines against human immunodeficiency virus type 1 (HIV-1) is the virus genetic diversity. For T-cell vaccine, this can be tackled by focusing the vaccine-elicited T-cells on the highly functionally
Publikováno v:
Clinical and Vaccine Immunology : CVI
A likely requirement for a protective vaccine against human immunodeficiency virus type 1 (HIV-1)/AIDS is, in addition to eliciting antibody responses, induction of effective T cells. To tackle HIV-1 diversity by T-cell vaccines, we designed an immun
Autor:
Ceri Alan Fielding, Sarah Nicol Lauder, Mathew Clement, Beatrice Ondondo, Philip R. Taylor, James P. Hindley, Kathryn Smart, Anja Bloom, Awen Gallimore, Anwen Sian Williams, Emma Jones, Simon Arnett Jones, Andrew James Godkin
Publikováno v:
European Journal of Immunology. 43:2613-2625
Balancing the generation of immune responses capable of controlling virus replication with those causing immunopathology is critical for the survival of the host and resolution of influenza-induced inflammation. Based on the capacity of interleukin-6
Autor:
Adrian V. S. Hill, Jill Gilmour, Peter Hayes, Lucy Dorrell, Nicola Borthwick, Umar Ebrahimsa, A P Black, Andrew J. McMichael, Maximillian Rosario, Anne Bridgeman, Eleanor Berrie, Beatrice Ondondo, A Rose, Nicole Frahm, Emma Jo Hayton, Tomáš Hanke, Stefano Colloca, Josephine H. Cox, Alfredo Nicosia, T Ahmed, Sarah Moyle
Virus diversity and escape from immune responses are the biggest challenges to the development of an effective vaccine against HIV-1. We hypothesized that T-cell vaccines targeting the most conserved regions of the HIV-1 proteome, which are common to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef91be46e4d25a6e9090d33a17bb81f
https://ora.ox.ac.uk/objects/uuid:3e4bd652-28c3-45ee-b404-6946fda6d996
https://ora.ox.ac.uk/objects/uuid:3e4bd652-28c3-45ee-b404-6946fda6d996
Autor:
Thomas J. Scriba, Lucy Dorrell, Annie Suttill, Andrew J. McMichael, Beatrice Ondondo, Rebecca Sutherland, Helen McShane, Christopher P. Conlon, Sarah Fidler, Hongbing Yang, Nicola Robinson
OBJECTIVE: To determine whether long-term HAART in chronic HIV-1 infection restores fully functional Mycobacterium tuberculosis (MTB)-specific CD4 T-cell responses. DESIGN: A cross-sectional study of HIV-1-seropositive subjects on continuous HAART fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e236f72d3d84c332e8c6723e67a277d2
https://ora.ox.ac.uk/objects/uuid:5361d6de-f53b-489a-ab46-7f7800342b7d
https://ora.ox.ac.uk/objects/uuid:5361d6de-f53b-489a-ab46-7f7800342b7d
Autor:
Beatrice Ondondo, Lucy Dorrell, Kevin Peterson, Assan Jaye, Hilton Whittle, Matthew Cotten, Sarah Rowland-Jones
Publikováno v:
European Journal of Immunology. 38:3549-3560
Majority of HIV-2-infected individuals meet the criteria of long-term non-progressors. This has been linked to superior qualitative HIV-2-specific cellular immune responses that correlate with viral control. However, it is unknown whether this is due
Autor:
James P. Hindley, Beatrice Ondondo, Emily J. Colbeck, Bernhard Moser, Emma Jones, Kathryn Smart, Sarah Nicol Lauder, Andrew James Godkin, Awen Gallimore, Ann Ager
Publikováno v:
Immunology
The frequency of CD4+ Foxp3+ regulatory T (Treg) cells is often significantly\ud increased in the blood of tumour-bearing mice and people with\ud cancer. Moreover, Treg cell frequencies are often higher in tumours compared\ud with blood and lymphoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72568006436d9e7b297d2a3aaadbc855
Autor:
Beatrice Ondondo
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 5 (2014)
Frontiers in Microbiology, Vol 5 (2014)
Development of an effective HIV/AIDS vaccine remains a big challenge, largely due to the enormous HIV diversity which propels immune escape. Thus novel vaccine strategies are targeting multiple variants of conserved antibody and T cell epitopic regio