Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Beatrice N. Engelsberg"'
Autor:
William R. Abrams, Joel Rosenbloom, Arthur J. Cohen, J. Charles Whitbeck, Paul C. Billings, Beatrice N. Engelsberg, Christopher S. Adams, Pamela S. Howard
Publikováno v:
Journal of Biological Chemistry. 277:28003-28009
Proper growth and development require the orderly synthesis and deposition of individual components of the extracellular matrix (ECM) into well ordered networks. Once formed, the ECM maintains tissue structure and houses resident cells. One ECM compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61f455e835a5ae7c4aa2adc7da79196
https://doi.org/10.1074/jbc.m106837200
https://doi.org/10.1074/jbc.m106837200
Autor:
Joel Rosenbloom, Paul C. Billings, Pamela S. Howard, Umberto Kucich, William R. Abrams, Beatrice N. Engelsberg, David J. Herrick, Edward J. Macarak
Publikováno v:
Journal of Cellular Biochemistry. 79:261-273
The extracellular matrix (ECM) plays an essential role in bladder structure and function. In this study, expression of beta ig-h3, a recently identified extracellular matrix protein, was investigated in human bladder tissue, and human bladder smooth-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64de6fdf999c1235683766fcfbd7b615
https://doi.org/10.1002/1097-4644(20001101)79:2<261::aid-jcb90>3.0.co
https://doi.org/10.1002/1097-4644(20001101)79:2<261::aid-jcb90>3.0.co
Publikováno v:
Toxicology and Applied Pharmacology. 141:532-539
The HMG box domain is a DNA binding domain present in the nonhistone chromosomal proteins HMG1 and HMG2 and in other proteins involved in the regulation of gene expression. Previous studies have demonstrated that HMG1 and HMG2 bind with high affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf052a3726a156ba40eeb7d25029b26
https://doi.org/10.1006/taap.1996.0319
https://doi.org/10.1006/taap.1996.0319
Publikováno v:
Cancer Chemotherapy and Pharmacology. 38:163-168
Cisplatin (CDDP) is an effective and widely used cancer chemotherapy drug. High mobility group (HMG) proteins 1 and 2 have been shown to bind with high affinity to CDDP-DNA. In this study we analyzed the interaction of HMG proteins with CDDP-DNA. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782c7cdc30a536e6b3131a74e2883715
https://doi.org/10.1007/s002800050465
https://doi.org/10.1007/s002800050465
Publikováno v:
Journal of Biological Chemistry. 268:23940-23945
Cisplatin (CDDP) is an effective cancer chemotherapeutic drug used in the treatment of several human malignancies. The effectiveness of cisplatin therapy is limited by intrinsic resistance of tumors to this drug as well as the development of secondar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7911f50d1ab25fecefcc2fb965bd1609
https://doi.org/10.1016/s0021-9258(20)80475-x
https://doi.org/10.1016/s0021-9258(20)80475-x
Publikováno v:
Journal of Biological Chemistry. 267:13520-13527
The biochemical processes responsible for the recognition and repair of cisplatin-damaged DNA in human cells are not well understood. We have developed a damaged DNA affinity precipitation technique that allows the direct visualization and characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d774184ba12e0f1e59458434ce832a17
https://doi.org/10.1016/s0021-9258(18)42242-9
https://doi.org/10.1016/s0021-9258(18)42242-9
Autor:
Pamela S. Howard, Paul C. Billings, Umberto Kucich, Joel Rosenbloom, David J. Herrick, Beatrice N. Engelsberg
Publikováno v:
American journal of respiratory cell and molecular biology. 22(3)
Bronchial smooth muscle cells play a central role in normal lung physiology by controlling airway tone. In addition, airway smooth muscle hyperplasia and hypertrophy are important factors in the pathophysiology of asthma. In this study, expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aef9ea50c0f8717fbf2cdb3286d5c0b
https://pubmed.ncbi.nlm.nih.gov/10696072
https://pubmed.ncbi.nlm.nih.gov/10696072
Autor:
Jian Fei Wang, Harry Rozmiarek, Steven W. Johnson, Paul C. Billings, Charlotte M. Witmer, Beatrice N. Engelsberg, William C. Merrick
Publikováno v:
Archives of toxicology. 71(7)
The elongation factor complex, EF-1H, serves an essential function in protein biosynthesis in eukaryotic cells, although the role of EF-1H in other physiological processes is unknown. In this report, we demonstrate that three components of EF-1H (EF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ab80efec08959c750ee40664df6f85
https://pubmed.ncbi.nlm.nih.gov/9209691
https://pubmed.ncbi.nlm.nih.gov/9209691
Publikováno v:
Cancer investigation. 12(6)
Cisplatin (CDDP) is a highly effective, frequently used cancer chemotherapeutic drug employed in the treatment of several human malignancies including ovarian, testicular, and bladder cancers. A common problem encountered with cisplatin therapy is in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c900a272c1a24709bc3f8312351a46d2
https://pubmed.ncbi.nlm.nih.gov/7994594
https://pubmed.ncbi.nlm.nih.gov/7994594
Autor:
Kirsten A. Skov, Richard J. Davis, Paul C. Billings, Edward N. Hughes, Beatrice N. Engelsberg
Publikováno v:
Biochemical and biophysical research communications. 188(3)
cis-Diamminedichloroplatinum (II) (cisplatin, CDDP) is a widely used chemotherapeutic agent. While many tumors are highly responsive to CDDP, certain tumors are resistant to this drug, limiting its efficacy. The anti-tumor activity of CDDP is believe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d195297950ceca30459c27ad715617
https://pubmed.ncbi.nlm.nih.gov/1445361
https://pubmed.ncbi.nlm.nih.gov/1445361