Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Beatrice Mintz"'
Publikováno v:
Melanoma Research. 14:555-562
Melanomas are promising targets for immunotherapy, as they express a number of tissue-specific antigens against which immune responses can be elicited. We have previously described transgenic mice in which malignant cutaneous melanomas are produced.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42b3f0ed4f481912489106792ab6d49
https://doi.org/10.1097/00008390-200412000-00019
https://doi.org/10.1097/00008390-200412000-00019
Publikováno v:
Journal of Immunological Methods. 264:153-162
Murine dendritic cells (DCs) are widely used for experimental vaccinations in mouse models. A high-yield method for freezing and thawing batches of these cells, if compatible with retention of cell immunophenotype, would reduce the time required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbcd055902ba61bea8e61e56e324d1c
https://doi.org/10.1016/s0022-1759(02)00100-x
https://doi.org/10.1016/s0022-1759(02)00100-x
Publikováno v:
Proceedings of the National Academy of Sciences. 94:7561-7565
The expression of cell-specialization genes is likely to be changing in tumor cells as their differentiation declines. Functional changes in these genes might yield unusual peptide epitopes with anti-tumor potential and could occur without modificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a94758fb4bb0223d6f58672fe1081ce5
https://doi.org/10.1073/pnas.94.14.7561
https://doi.org/10.1073/pnas.94.14.7561
Publikováno v:
Biochemical and Biophysical Research Communications. 236:173-177
The decline in cell differentiation commonly associated with malignant progression may be due in part to an increase in alternative splicing of the pre-mRNAs of tissue-specific genes. As a necessary basis for investigating this possibility in a murin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2623f873677132802bbd3527dc10c0f
https://doi.org/10.1006/bbrc.1997.6925
https://doi.org/10.1006/bbrc.1997.6925
Publikováno v:
Genomics. 37:245-248
The c2j albino mutation at the mouse tyrosinase locus arose spontaneously in the C57BL/6 inbred strain and causes complete absence of melanin synthesis, as does the "classical" c mutation of long-established albino inbred strains. Sequence analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d31ac7ce3f12b29f908b77d0ad84c82
https://doi.org/10.1006/geno.1996.0551
https://doi.org/10.1006/geno.1996.0551
Autor:
Beatrice Mintz, Willys K. Silvers
Publikováno v:
Proceedings of the National Academy of Sciences. 90:8817-8821
Tyr-SV40E transgenic mice are specifically susceptible to melanoma due to expression of the oncogene in pigment cells. Mice of the more susceptible lines die young of early-onset eye melanomas, when skin melanomas are still infrequent and benign. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d51c62a0fef874f7b21b25cfc63723
https://doi.org/10.1073/pnas.90.19.8817
https://doi.org/10.1073/pnas.90.19.8817
Autor:
Andres J. Klein-Szanto, Beatrice Mintz
Publikováno v:
Proceedings of the National Academy of Sciences. 89:11421-11425
Eye tumors of the retinal pigment epithelium (RPE) have been thought generally to be benign, whereas choroidal ones are malignant. To test this assumption in mice, the W/Wv (Kit) mutant genotype was introduced into melanoma-prone transgenic mice whos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81c4c8c8ff5816911f12ff4301d816e
https://doi.org/10.1073/pnas.89.23.11421
https://doi.org/10.1073/pnas.89.23.11421
Publikováno v:
Proceedings of the National Academy of Sciences. 89:7816-7820
The W/Kit mouse locus, affecting proliferation and survival of pigment cells, blood cells, and germ cells, is known to encode a tyrosine kinase growth factor receptor and is considered a protooncogene; yet it has not heretofore been causally implicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad39b123f109557b6bb2a97725d4dc8c
https://doi.org/10.1073/pnas.89.16.7816
https://doi.org/10.1073/pnas.89.16.7816
Autor:
Monika Bradl, Beatrice Mintz
Publikováno v:
Proceedings of the National Academy of Sciences. 88:9643-9647
Genetically albino mouse eggs were injected with an inducible transgene comprising the wild-type tyrosinase (monophenol, L-dopa: oxygen oxidoreductase, EC 1.14.18.1) cDNA and the metallothionein gene promoter in the expectation that the transgene wou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daef87e433ca8d11072f0367f5c83ef5
https://doi.org/10.1073/pnas.88.21.9643
https://doi.org/10.1073/pnas.88.21.9643
Autor:
Susan Porter, Beatrice Mintz
Publikováno v:
Gene. 97:277-282
We have isolated and characterized tyrosinase-specific cDNAs from wild-type mouse skin, to provide a basis for the structural and functional analysis of mutations at the mouse tyrosinase-encoding (Tyr) locus. The cDNAs were synthesized by the polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252f7338a2b3cf12b41697dfad37586c
https://doi.org/10.1016/0378-1119(91)90063-h
https://doi.org/10.1016/0378-1119(91)90063-h