Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Beatrice Malacrida"'
Autor:
Florian Laforêts, Panoraia Kotantaki, Beatrice Malacrida, Samar Elorbany, Ranjit Manchanda, Emmanuel Donnadieu, Frances Balkwill
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106514- (2023)
Summary: Studies of the high-grade serous ovarian cancer (HGSOC) tumor microenvironment, the most lethal gynecological cancer, aim to enhance the efficiency of established therapies. Cell motility is an important process of anti-tumor response. Using
Externí odkaz:
https://doaj.org/article/4d987d96496c49cc950f690163d0635b
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101086- (2022)
Summary: Three-dimensional (3D), multicellular in vitro models provide a useful platform for studying human cancer biology, particularly through deconvolution of the tumor microenvironment, or where animal models do not recapitulate the human conditi
Externí odkaz:
https://doaj.org/article/bab39619a3de40b4837c4561809b9b47
Autor:
Robin M. Delaine-Smith, Eleni Maniati, Beatrice Malacrida, Sam Nichols, Reza Roozitalab, Roanne R. Jones, Laura S.M. Lecker, Oliver M.T. Pearce, Martin M. Knight, Frances R. Balkwill
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102674- (2021)
Summary: In a multi-level “deconstruction” of omental metastases, we previously identified a prognostic matrisome gene expression signature in high-grade serous ovarian cancer (HGSOC) and twelve other malignancies. Here, our aim was to understand
Externí odkaz:
https://doaj.org/article/6068ad32821044adbec1edf7e797e977
Autor:
Beatrice Malacrida, Sam Nichols, Eleni Maniati, Roanne Jones, Robin Delanie-Smith, Reza Roozitalab, Eleanor J. Tyler, Morgan Thomas, Gina Boot, Jonas Mackerodt, Michelle Lockley, Martin M. Knight, Frances R. Balkwill, Oliver M.T. Pearce
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102676- (2021)
Summary: Guided by a multi-level “deconstruction” of omental metastases, we developed a tetra (four cell)-culture model of primary human mesothelial cells, fibroblasts, adipocytes, and high-grade serous ovarian cancer (HGSOC) cell lines. This mul
Externí odkaz:
https://doaj.org/article/99a346004e8b4e63bd0a6643a5d15ba8
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The histone H3 CENP-A is known to play a role during meiosis but its role in the testes in the fly is unknown. Here, the authors identify the mitochondrial metabolic protein complex ATP synthase F1 as interacting with CENP-A, promoting centromere coh
Externí odkaz:
https://doaj.org/article/fc77478783b448eba6143a43c99d1125
Autor:
Amira F. Mahdi, Beatrice Malacrida, Joanne Nolan, Mary E. McCumiskey, Anne B. Merrigan, Ashish Lal, Shona Tormey, Aoife J. Lowery, Kieran McGourty, Patrick A. Kiely
Publikováno v:
Cells, Vol 9, Iss 7, p 1582 (2020)
When breast cancer progresses to a metastatic stage, survival rates decline rapidly and it is considered incurable. Thus, deciphering the critical mechanisms of metastasis is of vital importance to develop new treatment options. We hypothesize that s
Externí odkaz:
https://doaj.org/article/fe9f9bc55c7740a4947120c8359f5614
Autor:
Irene Olivera, Rebeca Sanz-Pamplona, Elixabet Bolaños, Inmaculada Rodriguez, Iñaki Etxeberria, Assunta Cirella, Josune Egea, Saray Garasa, Itziar Migueliz, Iñaki Eguren-Santamaria, Miguel F. Sanmamed, Javier Glez-Vaz, Arantza Azpilikueta, Maite Alvarez, María C. Ochoa, Beatrice Malacrida, David Propper, Carlos E. de Andrea, Pedro Berraondo, Frances R. Balkwill, Álvaro Teijeira, Ignacio Melero
Publikováno v:
Cancer Discovery. 12:2140-2157
Interleukin-8 (CXCL8) produced in the tumor microenvironment correlates with poor response to checkpoint inhibitors and is known to chemoattract and activate immunosuppressive myeloid leukocytes. In human cancer, IL8 mRNA levels correlate with IL1B a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25b55e5706c4705e0a55ff724dfb496
https://doi.org/10.1158/2159-8290.cd-21-1115
https://doi.org/10.1158/2159-8290.cd-21-1115
Autor:
Ignacio Melero, Álvaro Teijeira, Frances R. Balkwill, Pedro Berraondo, Carlos E. de Andrea, David Propper, Beatrice Malacrida, María C. Ochoa, Maite Alvarez, Arantza Azpilikueta, Javier Glez-Vaz, Miguel F. Sanmamed, Iñaki Eguren-Santamaria, Itziar Migueliz, Saray Garasa, Josune Egea, Assunta Cirella, Iñaki Etxeberria, Inmaculada Rodriguez, Elixabet Bolaños, Rebeca Sanz-Pamplona, Irene Olivera
Supplementary Figure from A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα, and IL-1β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f32d8b6c5cd605ff447850ccc7e59f0
https://doi.org/10.1158/2159-8290.22541500.v1
https://doi.org/10.1158/2159-8290.22541500.v1
Autor:
Ignacio Melero, Álvaro Teijeira, Frances R. Balkwill, Pedro Berraondo, Carlos E. de Andrea, David Propper, Beatrice Malacrida, María C. Ochoa, Maite Alvarez, Arantza Azpilikueta, Javier Glez-Vaz, Miguel F. Sanmamed, Iñaki Eguren-Santamaria, Itziar Migueliz, Saray Garasa, Josune Egea, Assunta Cirella, Iñaki Etxeberria, Inmaculada Rodriguez, Elixabet Bolaños, Rebeca Sanz-Pamplona, Irene Olivera
Interleukin-8 (CXCL8) produced in the tumor microenvironment correlates with poor response to checkpoint inhibitors and is known to chemoattract and activate immunosuppressive myeloid leukocytes. In human cancer, IL8 mRNA levels correlate with IL1B a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968f3422d851bd514a8234d09869527b
https://doi.org/10.1158/2159-8290.c.6549661
https://doi.org/10.1158/2159-8290.c.6549661
Autor:
Florian Laforets, Panoraia Kotantaki, Beatrice Malacrida, Samar Elorbany, Ranjit Manchanda, Emmanuel Donnadieu, Frances Balkwill
Publikováno v:
Cancer Research. 83:5913-5913
Cell motility is an important component of anti-tumor responses, allowing immune cells like myeloid and cytotoxic T cells to infiltrate tumors. Using ex vivo human and mouse high-grade serous ovarian cancer (HGSOC) tumor slices combined with time-lap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc678d8620ae3d7b7885086ab77930ee
https://doi.org/10.1158/1538-7445.am2023-5913
https://doi.org/10.1158/1538-7445.am2023-5913