Výsledky vyhledávání - "Beatrice Chelli"

Human Neuronal SHSY5Y Cells on PVDF:PTrFE Copolymer Thin Films

Autor: Eva Bystrenova, Pierpaolo Greco, Dago M. de Leeuw, Beatrice Chelli, Ilaria Tonazzini, Fabio Biscarini

Publikováno v: Advanced Engineering Materials. 17:1051-1056

Here, we investigate the in vitro biocompatibility of polyvinylidenefluoride (PVDF)–polytrifluoroethylene (PTrFE) copolymer thin films using neuronal cells. The aim is to obtain an optimal capping layer material for hybrid bio-organic electronic tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ccfaa74227b45629ec13d325d60cddb
https://doi.org/10.1002/adem.201400441

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Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABAA receptor activity

Autor: Federico Da Settimo, Nicola Simola, Micaela Morelli, Marco Maccheroni, Barbara Costa, Francesca Simorini, Michele Luisi, Sabrina Taliani, Eleonora Da Pozzo, Claudia Martini, Beatrice Chelli

Publikováno v: Università di Pisa-IRIS
Psychoneuroendocrinology 36 (2011): 463–472.
info:cnr-pdr/source/autori:B. Costa, E. Da Pozzo, B. Chelli, N. Simola, M. Morelli, M. Luisi, M. Maccheroni, S. Taliani, F. Simorini, F. Da Settimo, C. Martini/titolo:Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: stimulation of in vitro neurosteroid production affecting GABAA receptor activity/doi:/rivista:Psychoneuroendocrinology/anno:2011/pagina_da:463/pagina_a:472/intervallo_pagine:463–472/volume:36

Summary A number of neurosteroids have been demonstrated to exert anxiolytic properties by means of a positive modulation of inhibitory GABAergic neurotransmission. The observation that neurosteroid synthesis can be pharmacologically regulated by lig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3548c17813f9dc0bbfafaf5a5edbef
https://doi.org/10.1016/j.psyneuen.2010.07.021

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Structure-activity relationship of acridine derivatives to amyloid aggregation of lysozyme

Autor: Ján Imrich, Fabio Biscarini, Pavol Kristian, Andrea Antosova, Zuzana Gazova, Mária Vilková, Francesco Valle, Beatrice Chelli, Eva Bystrenova, Katarina Siposova

Publikováno v: Biochimica et biophysica acta. G, General subjects
1810 (2010): 465–474. doi:10.1016/j.bbagen.2011.01.007
info:cnr-pdr/source/autori:Andrea Antosova (1), Beatrice Chelli (2), Eva Bystrenova (2), Katarina Siposova (1), Francesco Valle (2), Jan Imrich (3), Maria Vilkova (3), Pavol Kristian (3), Fabio Biscarini (2), Zuzana Gazova (1)/titolo:Structure-activity relationship of acridine derivatives to amyloid aggregation of lysozyme/doi:10.1016%2Fj.bbagen.2011.01.007/rivista:Biochimica et biophysica acta. G, General subjects (Print)/anno:2010/pagina_da:465/pagina_a:474/intervallo_pagine:465–474/volume:1810

Background Amyloid-related diseases (such as Alzheimer's disease or diabetes type II) are associated with self-assembly of protein into amyloid aggregates. Methods Spectroscopic and atomic force microscopy were used to determine the ability of acridi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b330be3e3e346ece31994201715420e9
https://doi.org/10.1016/j.bbagen.2011.01.007

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Structure-Based Optimization of Pyrazolo[3,4-d]pyrimidines as Abl Inhibitors and Antiproliferative Agents toward Human Leukemia Cell Lines

Autor: Emmanuele Crespan, Chiara Brullo, Giovanni Maga, M Magnani, Maria Letizia Trincavelli, Silvia Schenone, Francesco Bondavalli, Antonella Naldini, Claudia Martini, Fabrizio Manetti, Fabio Carraro, Maurizio Botta, Francesca Mosci, Beatrice Chelli, Olga Bruno

Publikováno v: Journal of Medicinal Chemistry. 51:1252-1259

Results from molecular docking calculations and Grid mapping laid the foundations for a structure-based optimization approach to improve the biological properties of pyrazolo-pyrimidine derivatives in terms of inhibition of Abl enzymatic activity and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1bc89fa34a63701efe572e3cb446e8
https://doi.org/10.1021/jm701240c

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Organic ultra-thin film transistors with a liquid gate for extracellular stimulation and recording of electric activity of stem cell-derived neuronal networks

Autor: Marianna Barbalinardo, Tobias Cramer, Mauro Murgia, Dago M. de Leeuw, Eva Bystrenova, Fabio Biscarini, Beatrice Chelli

Electronic transducers of neuronal cellular activity are important devices in neuroscience and neurology. Organic field-effect transistors (OFETs) offer tailored surface chemistry, mechanical flexibility, and high sensitivity to electrostatic potenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b18fda9ed9074d54ab9535f2bffc4fd
http://hdl.handle.net/11585/511770

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N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor

Autor: Maria Paola Patrizi, Federico Da Settimo, Sabrina Taliani, Giampaolo Primofiore, Ettore Novellino, Francesca Simorini, Giovanni Greco, Claudia Martini, Barbara Costa, Beatrice Chelli, Enrico Abignente

Publikováno v: Journal of Medicinal Chemistry. 47:1852-1855

We report the synthesis and the affinity data at both the peripheral (PBR) and the central benzodiazepine receptors of a series of N,N-dialkyl-2-phenylindol-3-ylglyoxylamide derivatives III, designed as conformationally constrained analogues of 2-phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d0f53c9348ea3aa8325192fc9784eb
https://doi.org/10.1021/jm030973k

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Neural cell alignment by patterning gradients of the extracellular matrix protein laminin

Autor: Michele Bianchi, Eva Bystrenova, Pierpaolo Greco, Marianna Barbalinardo, Fabio Biscarini, Beatrice Chelli, Francesco Valle

Publikováno v: Interface focus. 4(1)

Anisotropic orientation and accurate positioning of neural cells is achieved by patterning stripes of the extracellular matrix protein laminin on the surface of polystyrene tissue culture dishes by micromoulding in capillaries (MIMICs). Laminin conce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eeb4bda66685fd1ae32c3c3243b8144
https://pubmed.ncbi.nlm.nih.gov/24501672

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Peripheral-type benzodiazepine receptor ligands

Autor: Vittorio Gremigni, F Salvetti, Claudia Martini, Beatrice Chelli, Antonio Lucacchini, Alessandra Falleni

Publikováno v: Biochemical Pharmacology. 61:695-705

Strong evidence is emerging that mitochondrial permeability transition (MPT) may be important in certain physiological conditions and, above all, in the processes of cell damage and death. Reversible MPT, triggered by inducing agents in the presence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b6026cfcee310cf75441ce57602a736
https://doi.org/10.1016/s0006-2952(00)00588-8

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Unconventional Multi-Scale Patterning of Titanium Dioxide: A New Tool for the Investigation of Cell-Topography Interaction

Autor: Chiara Dionigi, Eva Bystrenova, Pierpaolo Greco, Francesco Valle, Michele Bianchi, Beatrice Chelli, Fabio Biscarini

Publikováno v: Advanced engineering materials
14 (2012): B208–B215. doi:10.1002/adem.201180061
info:cnr-pdr/source/autori:F. Biscarini, M. Bianchi, B. Chelli, F. Valle, C. Dionigi, E. Bystrenova, P. Greco/titolo:Unconventional Multi-Scale Patterning of Titanium Dioxide: A New Tool for the Investigation of Cell-Topography Interaction/doi:10.1002%2Fadem.201180061/rivista:Advanced engineering materials (Print)/anno:2012/pagina_da:B208/pagina_a:B215/intervallo_pagine:B208–B215/volume:14

Titanium dioxide (TiO2) is a biocompatible material with important applications in the field of regenerative medicine. Here we show that a multi-scale hierarchical architecture of TiO2, realized with sub-micrometer polystyrene beads as templating age

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8af61000d8ce2bca994d82bd3d7f02
https://publications.cnr.it/doc/192752

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Role of translocator protein (18 kDa) in adult separation anxiety and attachment style in patients with depression

Autor: Stefano Pini, P Gabelloni, G.B. Cassano, Claudia Martini, Antonio Lucacchini, Barbara Costa, Beatrice Chelli, Lisa Lari, S. Calugi, Marianna Abelli, Alessandra Cardini, E Da Pozzo

Publikováno v: Scopus-Elsevier
Current molecular medicine (2012).
info:cnr-pdr/source/autori:Costa B, Pini S, Abelli M, Gabelloni P, Da Pozzo E, Chelli B, Calugi S, Lari L, Cardini A, LucacchiniA, Casano GB, Martini C/titolo:Role of translocator protein (18Kda) in adult separation anxiety and attachment style in patients with depression/doi:/rivista:Current molecular medicine/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume

Background and Objectives: A role for the protein that mediates the rate-limiting step of steroidogenesis, the 18 kDa Translocator Protein (TSPO), has been suggested in the pathophysiology of Adult Separation Anxiety Disorder (ASAD). It has been show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7ffb64c0502240225be285c632b770
https://pubmed.ncbi.nlm.nih.gov/22348616

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