Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Beatrice, Thier"'
Autor:
Kim Denise Fischer, Shashank Tiwari, Beatrice Thier, Lin Christina Qiu, Tzu-Chen Lin, Annette Paschen, Jochen Imig
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Melanoma is a highly malignant tumor, that stands as the most lethal form of skin cancer and is characterized by notable phenotypic plasticity and intratumoral heterogeneity. Melanoma plasticity is involved in tumor growth, metastasis and therapy res
Externí odkaz:
https://doaj.org/article/8d8688860dd44810ae450695d526d633
Autor:
Dirk Schadendorf, Antje Sucker, Johannes Koch, Fang Zhao, Susanne Horn, Beatrice Thier, Simone Stupia, Alicia Brüggemann, Nina Schulze, Christoph Coch, Gunther Hartmann, Annette Paschen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/a455cc172a084acda6e1751b28b18d59
Autor:
Beatrice Thier, Annette Paschen
Publikováno v:
Cell Stress, Vol 5, Iss 2, Pp 26-28 (2021)
In recent years, therapy with immune modulating antibodies, termed immune checkpoint blockade (ICB), has revolutionized the treatment of advanced metastatic melanoma, yielding long-lasting clinical responses in a subgroup of patients. But despite thi
Externí odkaz:
https://doaj.org/article/cdd6d88e7beb4ab2b78e3c96e60f242a
Autor:
Hilal Bhat, Gregor Zaun, Thamer A. Hamdan, Judith Lang, Tom Adomati, Rosa Schmitz, Sarah-Kim Friedrich, Michael Bergerhausen, Lamin B. Cham, Fanghui Li, Murtaza Ali, Fan Zhou, Vishal Khairnar, Vikas Duhan, Tim Brandenburg, Yara Maria Machlah, Maximilian Schiller, Arshia Berry, Haifeng Xu, Jörg Vollmer, Dieter Häussinger, Beatrice Thier, Aleksandra A. Pandyra, Dirk Schadendorf, Annette Paschen, Martin Schuler, Philipp A. Lang, Karl S. Lang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immune activation within the tumor microenvironment is one promising approach to induce tumor regression. Certain viruses including oncolytic viruses such as the herpes simplex virus (HSV) and non-oncolytic viruses such as the lymphocytic choriomenin
Externí odkaz:
https://doaj.org/article/75601dc4b0134284b6d488ec8fac6ac6
Autor:
Simone Stupia, Christina Heeke, Alicia Brüggemann, Anne Zaremba, Beatrice Thier, Julia Kretz, Antje Sucker, Manuel Philip, Gennadiy Zelinskyy, Soldano Ferrone, Alexander Roesch, Susanne Horn, Eva Hadaschik, Dirk Schadendorf, Mirko Trilling, Ulf Dittmer, Klaus Griewank, Fang Zhao, Annette Paschen
Publikováno v:
Clinical Cancer Research.
Purpose: Recent studies have demonstrated HLA class II (HLA-II)-dependent killing of melanoma cells by cytotoxic CD4 T cells. We investigated evolution of HLA-II-loss tumors that escape cytotoxic CD4 T cell activity and contribute to immunotherapy re
Autor:
Si Zhu, Alexander Roesch, Beatrice Thier, Annette Paschen, Antje Sucker, Franziska Noelle Harbers, Simone Stupia, Vicky Peller, Marion Schwamborn, Katharina Fleischhauer, Yong Chen, Fang Zhao, Pietro Crivello, Heike Chauvistré, Dirk Schadendorf
Publikováno v:
Journal of Investigative Dermatology. 141:2480-2489
The highly plastic nature of melanoma enables its transition among diverse cell states to survive hostile conditions. However, the interplay between specific tumor cell states and intratumoral T cells remains poorly defined. With MAPK inhibitor‒tre
Autor:
Annette Paschen, Beatrice Thier
Publikováno v:
Cell Stress, Vol 5, Iss 2, Pp 26-28 (2021)
In recent years, therapy with immune modulating antibodies, termed immune checkpoint blockade (ICB), has revolutionized the treatment of advanced metastatic melanoma, yielding long-lasting clinical responses in a subgroup of patients. But despite thi
Autor:
Beatrice Thier, Sebastian Howe, Soldano Ferrone, Mirko Trilling, Halime Kalkavan, Robin Brinkhaus, Klaus G. Griewank, Antje Sucker, Lina Such, David Liu, Cathrin Ritter, Martin Schuler, Christoph Coch, Natalia Pieper, Hilal Bhat, Susanne Horn, Karl S. Lang, Johannes Köster, Dirk Schadendorf, Gunther Hartmann, Annette Paschen, Thomas A. Kufer, Jürgen C. Becker, Selma Ugurel, Vu Thuy Khanh Le-Trilling, Ulf Dittmer, Derek Liu, Ulrike Seifert, Fang Zhao, Eliezer M. Van Allen
Publikováno v:
Cell Stress
J Clin Invest
J Clin Invest
In recent years, therapy with immune modulating antibodies, termed immune checkpoint blockade (ICB), has revolutionized the treatment of advanced metastatic melanoma, yielding long-lasting clinical responses in a subgroup of patients. But despite thi
Autor:
Beatrice Thier, Fang Zhao, Simone Stupia, Alicia Brüggemann, Johannes Koch, Nina Schulze, Susanne Horn, Christoph Coch, Gunther Hartmann, Antje Sucker, Dirk Schadendorf, Annette Paschen
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e003863
BackgroundImmune-stimulatory agents, like agonists of the innate immune receptor RIG-I, are currently tested in clinical trials as an intratumoral treatment option for patients with unresectable melanoma, aiming to enhance anti-tumor T cell responses
Autor:
Franziska Noelle, Harbers, Beatrice, Thier, Simone, Stupia, Si, Zhu, Marion, Schwamborn, Vicky, Peller, Heike, Chauvistré, Pietro, Crivello, Katharina, Fleischhauer, Alexander, Roesch, Antje, Sucker, Dirk, Schadendorf, Yong, Chen, Annette, Paschen, Fang, Zhao
Publikováno v:
The Journal of investigative dermatology. 141(10)
The highly plastic nature of melanoma enables its transition among diverse cell states to survive hostile conditions. However, the interplay between specific tumor cell states and intratumoral T cells remains poorly defined. With MAPK inhibitor‒tre