Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Beatrice, Severino"'
Autor:
Giorgia Andreozzi, Angela Corvino, Beatrice Severino, Elisa Magli, Elisa Perissutti, Francesco Frecentese, Vincenzo Santagada, Giuseppe Caliendo, Ferdinando Fiorino
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1320 (2024)
Background: In recent decades, there has been a startling rise in the number of cancer patients worldwide, which has led to an amazing upsurge in the development of novel anticancer treatment candidates. On a positive note, arylpiperazines have garne
Externí odkaz:
https://doaj.org/article/04bd4eff63af4682b323a7288afe23a7
Autor:
José Britto-Júnior, Rafael Furlaneto, Antonio Tiago Lima, Mariana Gonçalves de Oliveira, Beatrice Severino, Francesco Frecentese, Ferdinando Fiorino, Giuseppe Caliendo, Marcelo Nicolás Muscará, Gilberto De Nucci
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: The human umbilical artery (HUA), rat-isolated right atrium, and rat-isolated vas deferens present a basal release of 6-nitrodopamine (6-ND). The basal release of 6-ND from these tissues was significantly decreased (but not abolished) w
Externí odkaz:
https://doaj.org/article/2f38f458f02f4026a5a5f710af3f2c29
Autor:
Angela Corvino, Elisabetta Granato, Antonia Scognamiglio, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Giuseppe Cirino, Ida Cerqua, Rocco Pavese, Antonio Petti, Francesca Pavese, Francesco Petti, Fiorentina Roviezzo, Beatrice Severino, Giuseppe Caliendo
Publikováno v:
Molecules, Vol 29, Iss 18, p 4514 (2024)
In this study, a new and straightforward process for the preparation of budesonide 21-phosphate (Bud-21P) and its disodium salt (Bud-21P-Na2) is described. The method results in a yield comparable to those obtained by diphosphoryl chloride, but it is
Externí odkaz:
https://doaj.org/article/a3abcecee4cf44e68dc1c62fe07cd798
Autor:
Rosa Sparaco, Pierfrancesco Cinque, Antonia Scognamiglio, Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Beatrice Severino, Paolo Luciano, Marcello Casertano, Anna Aiello, Gustavo Yuri Martins Viegas, Gilberto De Nucci, Francesco Frecentese
Publikováno v:
Molecules, Vol 29, Iss 7, p 1598 (2024)
4-Nitro and 7-nitro propranolol have been recently synthesized and characterized by us. (±)-4-NO2-propranolol has been shown to act as a selective antagonist of 6-nitrodopamine (6-ND) receptors in the right atrium of rats. As part of our follow-up t
Externí odkaz:
https://doaj.org/article/1faca57576ae452e9550a466612b7446
Autor:
Ida Cerqua, Elisabetta Granato, Angela Corvino, Beatrice Severino, Danilo D’Avino, Martina Simonelli, Elisa Perissutti, Antonia Scognamiglio, Davida Mirra, Bruno D’Agostino, Giuseppe Caliendo, Antonietta Rossi, Giuseppe Cirino, Chiara Maria Motta, Fiorentina Roviezzo
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Hydrogen sulfide (H2S) is emerging as an important potential therapeutic option for respiratory inflammatory diseases. In this study, we investigated the effectiveness of a novel corticosteroid derivative, that is chemically linked to a
Externí odkaz:
https://doaj.org/article/ebceb878295743ad82f57f721e77b614
Autor:
Giorgia Andreozzi, Maria Rosaria Ambrosio, Elisa Magli, Giovanni Maneli, Beatrice Severino, Angela Corvino, Rosa Sparaco, Elisa Perissutti, Francesco Frecentese, Vincenzo Santagada, Anna Leśniak, Magdalena Bujalska-Zadrożny, Giuseppe Caliendo, Pietro Formisano, Ferdinando Fiorino
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1483 (2023)
Arylpiperazines represent one of the most important classes of 5-HT1AR ligands and have attracted considerable interests for their versatile properties in chemistry and pharmacology, leading to the research of new derivatives that has been focused on
Externí odkaz:
https://doaj.org/article/f809eadae0904facb28d7ccc4163c291
Autor:
Angela Corvino, Valentina Citi, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Vincenzo Calderone, Alma Martelli, Era Gorica, Simone Brogi, Flavia Faganello Colombo, Caroline Nunes Capello, Heloisa Helena Araujo Ferreira, Maria Grazia Rimoli, Federica Sodano, Barbara Rolando, Francesca Pavese, Antonio Petti, Marcelo Nicolás Muscará, Giuseppe Caliendo, Beatrice Severino
Publikováno v:
Journal of Advanced Research, Vol 35, Iss , Pp 267-277 (2022)
Introduction: Hydrogen sulfide (H2S) is a fundamental biological endogenous gas-mediator in the respiratory system. It regulates pivotal patho-physiological processes such as oxidative stress, pulmonary circulation, airway tone and inflammation. Obje
Externí odkaz:
https://doaj.org/article/610e9a0c8bd745389a68efd1fc4472d6
Autor:
Tiziana Petrozziello, Francesca Boscia, Valentina Tedeschi, Anna Pannaccione, Valeria de Rosa, Angela Corvino, Beatrice Severino, Lucio Annunziato, Agnese Secondo
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background The cycad neurotoxin beta-methylamino-l-alanine (L-BMAA), one of the environmental trigger factor for amyotrophic lateral sclerosis/Parkinson-dementia complex (ALS/PDC), may cause neurodegeneration by disrupting organellar Ca2+ ho
Externí odkaz:
https://doaj.org/article/906b0019fd284affb8f235f1bb97c477
Autor:
Silvia Abigail Coavoy-Sánchez, Anderson Romério Azevedo Cerqueira, Simone Aparecida Teixeira, Vincenzo Santagada, Giorgia Andreozzi, Angela Corvino, Antonia Scognamiglio, Rosa Sparaco, Giuseppe Caliendo, Beatrice Severino, Soraia Katia Pereira Costa, Luis Carlos Spolidorio, Marcelo Nicolás Muscará
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1907 (2023)
Hydrogen sulfide (H2S) is particularly produced in the skin, where it participates in the regulation of inflammation, pruritus, cytoprotection, scarring, and angiogenesis. In this study, we compared the effects of dexamethasone (Dex) with two H2S-rel
Externí odkaz:
https://doaj.org/article/294603bc4e634dcdae188d8f6991cf83
Autor:
Valentina Citi, Angela Corvino, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Simone Brogi, Lorenzo Flori, Era Gorica, Lara Testai, Alma Martelli, Vincenzo Calderone, Giuseppe Caliendo, Beatrice Severino
Publikováno v:
Journal of Advanced Research, Vol 27, Iss , Pp 41-53 (2021)
Introduction: The gasotransmitter hydrogen sulphide (H2S), an endogenous ubiquitous signalling molecule, is known for its beneficial effects on different mammalian systems. H2S exhibits cardioprotective activity against ischemia/reperfusion (I/R) or
Externí odkaz:
https://doaj.org/article/8fc49f98c59742828951e1c1870ef95a