Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Beatrice, Noce"'
Autor:
Matteo Cassandri, Antonella Porrazzo, Silvia Pomella, Beatrice Noce, Clemens Zwergel, Francesca Antonella Aiello, Francesca Vulcano, Luisa Milazzo, Simona Camero, Deborah Pajalunga, Massimo Spada, Valeria Manzi, Giovanni Luca Gravina, Silvia Codenotti, Michela Piccione, Miriam Tomaciello, Michele Signore, Giovanni Barillari, Cinzia Marchese, Alessandro Fanzani, Biagio De Angelis, Concetta Quintarelli, Christopher R. Vakoc, Eleanor Y. Chen, Francesca Megiorni, Franco Locatelli, Sergio Valente, Antonello Mai, Rossella Rota, Francesco Marampon
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-20 (2024)
Abstract Radiotherapy (RT) plays a critical role in the management of rhabdomyosarcoma (RMS), the prevalent soft tissue sarcoma in childhood. The high risk PAX3-FOXO1 fusion-positive subtype (FP-RMS) is often resistant to RT. We have recently demonst
Externí odkaz:
https://doaj.org/article/d2578a217b0d469480a398078bb622c7
Autor:
Rossella Fioravanti, Veronica Rodriguez, Jonatan Caroli, Ugo Chianese, Rosaria Benedetti, Elisabetta Di Bello, Beatrice Noce, Clemens Zwergel, Davide Corinti, Dolores Viña, Lucia Altucci, Andrea Mattevi, Sergio Valente, Antonello Mai
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 973-985 (2022)
As regioisomers/bioisosteres of 1a, a 4-phenylbenzamide tranylcypromine (TCP) derivative previously disclosed by us, we report here the synthesis and biological evaluation of some (hetero)arylbenzoylamino TCP derivatives 1b-6, in which the 4-phenyl m
Externí odkaz:
https://doaj.org/article/93fcd4f9950b49e69e71b43501b4fcde
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Histone lysine-specific demethylase 1 (LSD1/KDM1A) was first identified in 2004 as an epigenetic enzyme able to demethylate specific lysine residues of histone H3, namely H3K4me1/2 and H3K9me1/2, using FAD as the cofactor. It is ubiquitously overexpr
Externí odkaz:
https://doaj.org/article/551fd67cf61f4151a228d7482690337a
Publikováno v:
CHIMIA, Vol 76, Iss 5 (2022)
Epigenetic modifications in eukaryotic biological pathways can lead to the up- or downregulation of regulatory proteins contributing to disease onset and progression. In the last three decades, histone deacetylases (HDACs) are among the most studied
Externí odkaz:
https://doaj.org/article/dc74cf61d80045d4b9ef04f4d85d54f4
Autor:
Beatrice Noce, Elisabetta Di Bello, Clemens Zwergel, Rossella Fioravanti, Sergio Valente, Dante Rotili, Andrea Masotti, Mohammad Salik Zeya Ansari, Daniela Trisciuoglio, Alokta Chakrabarti, Christophe Romier, Dina Robaa, Wolfgang Sippl, Manfred Jung, Cécile Häberli, Jennifer Keiser, Antonello Mai
Publikováno v:
ChemMedChem. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2c630a134388125c82bf2e083676802
https://doi.org/10.1002/cmdc.202300028
https://doi.org/10.1002/cmdc.202300028
Autor:
Beatrice Noce, Elisabetta Di Bello, Clemens Zwergel, Rossella Fioravanti, Sergio Valente, Dante Rotili, Andrea Masotti, Mohammad Salik Zeya Ansari, Daniela Trisciuoglio, Alokta Chakrabarti, Christophe Romier, Dina Robaa, Wolfgang Sippl, Manfred Jung, Cécile Häberli, Jennifer Keiser, Antonello Mai
Publikováno v:
ChemMedChem.
Schistosoma mansoni HDAC8 is a reliable target to fight schistosomiasis, and several inhibitors have been reported in the literature up to now. Nevertheless, only a few displayed selectivity over the human deacetylases and some exhibited very low or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ee091e77c00fc1207dc5ed27b896d7
https://pubmed.ncbi.nlm.nih.gov/36250286
https://pubmed.ncbi.nlm.nih.gov/36250286
Autor:
Marta Massari, Sara Marchese, Joana Reis, Lorenzo Basile, Greta Cascetta, Christoph Gorgulla, Beatrice Noce, Antonello Mai, Sergio Valente, Haribabu Arthanari, Andrea Mattevi
Publikováno v:
Free Radical Biology and Medicine. 201:59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1775e544a8f9d170b3770f1180a86812
https://doi.org/10.1016/j.freeradbiomed.2023.03.238
https://doi.org/10.1016/j.freeradbiomed.2023.03.238
Autor:
Elisabetta, Di Bello, Beatrice, Noce, Rossella, Fioravanti, Clemens, Zwergel, Sergio, Valente, Dante, Rotili, Giulia, Fianco, Daniela, Trisciuoglio, Marina M, Mourão, Policarpo, Sales, Suzanne, Lamotte, Eric, Prina, Gerald F, Späth, Cécile, Häberli, Jennifer, Keiser, Antonello, Mai
Publikováno v:
ACS infectious diseases. 8(7)
Neglected tropical diseases (NTDs), including trypanosomiasis, leishmaniasis, and schistosomiasis, result in a significant burden in terms of morbidity and mortality worldwide every year. Current antiparasitic drugs suffer from several limitations su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c138179b88dce37a07a1b09504bfc8e
https://pubmed.ncbi.nlm.nih.gov/35732073
https://pubmed.ncbi.nlm.nih.gov/35732073
Autor:
Elisabetta Di Bello, Beatrice Noce, Rossella Fioravanti, Clemens Zwergel, Sergio Valente, Dante Rotili, Giulia Fianco, Daniela Trisciuoglio, Marina M. Mourão, Policarpo Sales, Suzanne Lamotte, Eric Prina, Gerald F. Späth, Cécile Häberli, Jennifer Keiser, Antonello Mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9849e23039483f21b1806ea90ad9cb74
http://hdl.handle.net/11573/1650772
http://hdl.handle.net/11573/1650772
