Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Beate Wilhelm"'
Autor:
Simon K. P. Schmich, Jan Keck, Gabriel A. Bonaterra, Mirjam Bertoune, Anna Adam, Beate Wilhelm, Emily P. Slater, Hans Schwarzbach, Volker Fendrich, Ralf Kinscherf, Wulf Hildebrandt
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 912 (2023)
Cancer cachexia describes a syndrome of muscle wasting and lipolysis that is still largely untreatable and negatively impacts prognosis, mobility, and healthcare costs. Since upregulation of skeletal muscle monoamine-oxidase-A (MAO-A), a source of re
Externí odkaz:
https://doaj.org/article/5b2ac13955f04052bdc6cfd29b423b10
Autor:
Gabriel A. Bonaterra, Alexander Schleper, Maximilian Skowronek, Lucia S. Kilian, Theresa Rink, Hans Schwarzbach, Hendrik Heers, Jörg Hänze, Peter Rexin, Annette Ramaswamy, Carsten Denkert, Beate Wilhelm, Axel Hegele, Rainer Hofmann, Eberhard Weihe, Ralf Kinscherf
Publikováno v:
Cancers, Vol 14, Iss 19, p 4591 (2022)
Although growth differentiation factor-15 (GDF-15) is highly expressed in PCa, its role in the development and progression of PCa is unclear. The present study aims to determine the density of GDF-15+ cells and immune cells (M1-/M2 macrophages [MΦ],
Externí odkaz:
https://doaj.org/article/ea55ca9d15b64e05af184decc57b3138
Autor:
Wulf Hildebrandt, Jan Keck, Simon Schmich, Gabriel A. Bonaterra, Beate Wilhelm, Hans Schwarzbach, Anna Eva, Mirjam Bertoune, Emily P. Slater, Volker Fendrich, Ralf Kinscherf
Publikováno v:
Cells, Vol 11, Iss 10, p 1607 (2022)
Skeletal muscle wasting critically impairs the survival and quality of life in patients with pancreatic ductal adenocarcinoma (PDAC). To identify the local factors initiating muscle wasting, we studied inflammation, fiber cross-sectional area (CSA),
Externí odkaz:
https://doaj.org/article/196ab6715f994981a37de440f24a3cc0
Autor:
Aline Heduschke, Kathrin Ackermann, Beate Wilhelm, Lilli Mey, Gabriel Alejandro Bonaterra, Ralf Kinscherf, Anja Schwarz
Publikováno v:
Cells, Vol 10, Iss 9, p 2346 (2021)
(1) Background: Growth differentiation factor-15 (GDF-15) is associated with cardiovascular diseases and autophagy in human macrophages (MΦ). Thus, we are interested in investigating autophagic mechanisms with special respect to the role of GDF-15.
Externí odkaz:
https://doaj.org/article/942764591627467ca97baf72f94ce068
Autor:
Beate Wilhelm, Alain Thierstein
Publikováno v:
Raumforschung und Raumordnung, Vol 57, Iss 2-3 (1999)
Within the process of innovation, technology and knowledge transfers between universities and other research institutes and private industry have a vital role to play. It is especially important that the various players involved should interact withi
Externí odkaz:
https://doaj.org/article/d22a84de9c92441ab6fdd91b6db3adfd
Autor:
Gerhard Aumüller, Beate Wilhelm, Nishtman Dizeyi, Andreas Doll, Gunther Wennemuth, Per-Anders Abrahamsson
Publikováno v:
The Prostate. 72:326-337
Neuroendocrine (NE) cells are frequently present in the human prostate and urethra, whereas they are lacking in the other urogenital organs. This study was undertaken as there are only few detailed studies available on the distribution, form and func
Autor:
Adelaida G. Filoteo, Timo Brandenburger, Heidi Post, Anja Schwarz, Gerhard Aumüller, Beate Wilhelm, Emanuel E. Strehler, Ariel J. Caride
Publikováno v:
Journal of Biological Chemistry. 286:7938-7946
Ca(2+) and Ca(2+)-dependent signals are essential for sperm maturation and fertilization. In mouse sperm the plasma membrane Ca(2+)-ATPase (PMCA) isoform 4 plays a crucial role in Ca(2+) transport. The two major splice variants of PMCA4 are PMCA4a an
Publikováno v:
International Journal of Andrology. 33:775-783
The plasma membrane Ca(2+) -ATPase (PMCA) is the main restorer of Ca(2+) balance in sperm. Particularly, PMCA isoform 4 has an essential function in sperm fertility by its participation in gaining sperm hypermotility. PMCA activity is influenced by i
Autor:
Martin Hellmich, Christian Albus, Reinhard Griebenow, Harald Schicha, Karl Köhle, Peter Theissen, Demet Aslim, Beate Wilhelm
Publikováno v:
International Journal of Behavioral Medicine. 16:219-226
Recent advances in drug therapy question as to the additional impact behavioral interventions may have on the prognosis of patients with clinically stable coronary heart disease (CHD).The aim of the study was to evaluate the effects of a multimodal,
Publikováno v:
Histochemistry and Cell Biology. 129:331-343
It has recently been shown in mice that the plasma membrane Ca(2+)-ATPase isoform 4 (PMCA4) is essential for sperm fertilization capacity. We analyzed whether sperm PMCA4 is formed in the rat during spermatogenesis or is synthesized in the epididymis