Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Beate Muller-Tiemann"'
Autor:
S. Miranda, Peter Donner, M. A. A. Thomaz, Roman Hillig, Vera Pütter, Caterina Holz, Jörg Fanghänel, Uwe Eberspaecher, Maria Arménia Carrondo, Pedro M. Matias, Patrick Amstutz, Christine Lang, Kerstin Crusius, Maya Gulotti-Georgieva, Beate Muller-Tiemann, H. Kaspar Binz, Ursula Egner, Tiago M. Bandeiras, Arndt Schmitz
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 64:339-353
As a key regulator of mitosis, the Ser/Thr protein polo-like kinase-1 (Plk-1) is a well validated drug target in cancer therapy. In order to enable structure-guided drug design, determination of the crystal structure of the kinase domain of Plk-1 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f8b5b6e2a5898f1e802d4480ee6e5b
https://doi.org/10.1107/s0907444907068217
https://doi.org/10.1107/s0907444907068217
Autor:
Oliver von Ahsen, Ulrike Voigtmann, Beate Muller-Tiemann, Arndt Schottelius, Nikolay Nifantiev, Alexander Ernst, Karsten Parczyk, Monika Klotz
Publikováno v:
Analytical Biochemistry. 372:96-105
Fucosyltransferase VII (FucTVII) is a very promising drug target for treatment of inflammatory skin diseases. Its activity is required for synthesis of the sialyl-Lewis X glycoepitopes on the E- and P-selectin ligands, necessary for lymphocyte migrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09c083ca50b482fe627abed9b75ff15
https://doi.org/10.1016/j.ab.2007.08.029
https://doi.org/10.1016/j.ab.2007.08.029
Autor:
Felipe Monteclaro, Anne Mengel, Beate Muller-Tiemann, Ursula Egner, Duy Nguyen, Martina Huber, Uwe Eberspaecher, Roman C. Hillig
Publikováno v:
Journal of Molecular Biology. 372:562-563
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dfeb02d682ea8acdb9cc0f445ee972e
https://doi.org/10.1016/j.jmb.2007.03.081
https://doi.org/10.1016/j.jmb.2007.03.081