Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Beate Michely"'
Publikováno v:
Mechanisms of Development. 126
Autor:
Michael Gramlich, Christian Krohne, Brenda Gerull, Siegfried Labeit, Henk Granzier, Sabine Klaassen, Bryan D. Hudson, Beate Michely, Florian Kirchner, Bettina Erdmann, Ludwig Thierfelder, Arnd Heuser, Manuela Magarin, Mihail Todiras
Mutations in a variety of myofibrillar genes cause dilated cardiomyopathy (DCM) in humans, usually with dominant inheritance and incomplete penetrance. Here, we sought to clarify the functional effects of the previously identified DCM-causing TTN 2-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2b296da3f2e4dcb6d22c29dcfe9f6d
https://europepmc.org/articles/PMC2764556/
https://europepmc.org/articles/PMC2764556/
Autor:
Michael Gramlich, Beate Michely, Brenda Gerull, Christian Krohne, Ingo Morano, Siegfried Labeit, Ludwig Thierfelder
Publikováno v:
Circulation. 116
Dilated cardiomyopathy (DCM) is the most common form of primary myocardial diseases and the third most common cause of heart failure. Familial occurrence, mostly as an autosomal dominant trait, is responsible for 20 –30% of all DCM cases. We have p
Autor:
Patrick T. Ellinor, Jordan T. Shin, Bernhard Pilz, Arnd Heuser, Gregor Krings, Beate Michely, Sabine Sasse-Klaassen, Brenda Gerull, G. William Dec, Bruce Coplin, Bong Seok Song, Ludwig Thierfelder, Andrea Toeppel, Hans Christian Hennies, Danita M. Yoerger, Calum A. MacRae, Peter Lange, Susanne Probst
Publikováno v:
Journal of the American College of Cardiology. 48(1)
OBJECTIVES We sought to identify the genetic locus for an inherited form of dilated cardiomyopathy (DCM) that is characterized by diffuse myocardial fibrosis and sudden death. BACKGROUND Genetic studies have mapped multiple loci for DCM, which is a m
Autor:
Calum A. MacRae, Beate Michely, Katja S. Grossmann, Thomas Wichter, Craig T. Basson, Matthias Paul, Deborah A. McDermott, Walter Birchmeier, Günter Breithardt, Stefan Peters, Rainer Dietz, Bruce B. Lerman, Patrick T. Ellinor, Ludwig Thierfelder, Eric Schulze-Bahr, Sabine Sasse-Klaassen, Arnd Heuser, Brenda Gerull, Steve M Markowitz
Publikováno v:
Nature genetics. 36(11)
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with fibrofatty replacement of cardiac myocytes, ventricular tachyarrhythmias and sudden cardiac death. In 32 of 120 unrelated individuals with ARVC, we identified heterozygous muta
Publikováno v:
Biochemical and biophysical research communications. 292(3)
The widely expressed adhesion receptor CEACAM1 is a member of the carcinoembryonic antigen (CEA) family within the immunoglobulin (Ig) superfamily of glycoproteins. While the expression of transmembrane isoforms has been described in detail, only lit