Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Beate Müller-Tiemann"'
Autor:
Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier
PDF - 118K, Supplementary Table S1. Mesothelin staining intensity in FFPE tissues of human primary ovarian cancer, pancreatic cancer and mesothelioma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3851a39590f944f943652dd8cf92bb67
https://doi.org/10.1158/1535-7163.22499859
https://doi.org/10.1158/1535-7163.22499859
Autor:
Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier
Mesothelin is a tumor differentiation antigen frequently overexpressed in tumors such as mesothelioma, ovarian, pancreatic, and lung adenocarcinomas while showing limited expression in nonmalignant tissues. Mesothelin is therefore an attractive targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95b089c26fcbc4b0cf108dc63a5d571f
https://doi.org/10.1158/1535-7163.c.6536289
https://doi.org/10.1158/1535-7163.c.6536289
Autor:
Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier
PDF - 117K, Supplementary materials and methods, figure legends for supplementary figures and table.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa361393b3cb5e31d00a3feaf9fd65f
https://doi.org/10.1158/1535-7163.22499862.v1
https://doi.org/10.1158/1535-7163.22499862.v1
Autor:
Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier
PDF - 3895K, Supplementary Figure S1. Immunohistochemical detection of mesothelin expression in FFPE tissues of human primary ovarian cancer, pancreatic cancer, and mesothelioma. Supplementary Figure S2. Immunohistochemical detection of mouse mesothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f72be6cb23507a9f4a682280a4e7ea6
https://doi.org/10.1158/1535-7163.22499865
https://doi.org/10.1158/1535-7163.22499865
Autor:
Charlotte Christine Kopitz, Frank-Detlef Scholle, Christoph Schatz, Beate Müller-Tiemann, Iring Heisler, Sven Golfier, Beatrix Stelte-Ludwig, Kerstin Unterschemmann, Sandra Bruder, Anke Mayer-Bartschmid, Antje Kahnert, Bertolt Kreft, Lars Linden, Axel Harrenga, Peter Hauff, Karl Ziegelbauer
Publikováno v:
Molecular Cancer Therapeutics. 13:1537-1548
Mesothelin is a tumor differentiation antigen frequently overexpressed in tumors such as mesothelioma, ovarian, pancreatic, and lung adenocarcinomas while showing limited expression in nonmalignant tissues. Mesothelin is therefore an attractive targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb236c0141f5324ce372bbefd9b11c6
https://doi.org/10.1158/1535-7163.mct-13-0926
https://doi.org/10.1158/1535-7163.mct-13-0926
Autor:
Rainer Fischer, Dmitrij Hristodorov, Beate Müller-Tiemann, Heiner Apeler, Lars Linden, Hannah Joerissen
Publikováno v:
Molecular Biotechnology. 53:326-335
Monoclonal antibodies (mAbs) are the fastest growing class of biopharmaceuticals reflecting their diverse applications in research and the clinic. The correct glycosylation of mAbs is required to elicit effector functions such as complement-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c5edc695f6c4d9b169ae499d40f2b9
https://doi.org/10.1007/s12033-012-9531-x
https://doi.org/10.1007/s12033-012-9531-x
Publikováno v:
Proceedings of the National Academy of Sciences. 95:6079-6084
The DNA binding activity of p53 is crucial for its tumor suppressor function and is subject to tight regulation. Previous studies revealed that the inhibitory function of the p53 C terminus is implicated in the latent, low affinity sequence-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9252b8d2eef781b4c75fd4afd63ebdbb
https://doi.org/10.1073/pnas.95.11.6079
https://doi.org/10.1073/pnas.95.11.6079
Publikováno v:
Antibody Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22813d14541ec54096fc3ec3d853ea6b
https://doi.org/10.1142/9781848166295_0008
https://doi.org/10.1142/9781848166295_0008
Autor:
Guido A. Malawski, Arndt A.P. Schmitz, Martina Huber, Beate Müller-Tiemann, Kerstin Crusius, Roman C. Hillig, Ursula Egner, Uwe Eberspaecher, Felipe Monteclaro, Peter Donner
Publikováno v:
Protein science : a publication of the Protein Society. 15(12)
This study describes an efficient multiparallel automated workflow of cloning, expression, purification, and crystallization of a large set of construct variants for isolated protein domains aimed at structure determination by X-ray crystallography.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c3e016626880f16d311375127812f9
https://pubmed.ncbi.nlm.nih.gov/17132859
https://pubmed.ncbi.nlm.nih.gov/17132859
Autor:
Felipe Monteclaro, Mithra Mahmoudi, Brent Larsen, Tara Heitner, Bing Liu, Beate Müller-Tiemann, David Vogel, Xiao-Yan Zhao, Ying Zhu, Silke Finster, Hongxing Zhou, David R. Light, Kirk Mclean, Noboru Satozawa, Ronald R. Cobb
Publikováno v:
Journal of biomolecular screening. 11(8)
A therapeutic antibody candidate (AT-19) isolated using multivalent phage display binds native tomoregulin (TR) as a mul-timer not as a monomer. This report raises the importance of screening and selecting phage antibodies on native antigen and reemp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd6b83024a22c6d1faea1f531249c31
https://pubmed.ncbi.nlm.nih.gov/17092910
https://pubmed.ncbi.nlm.nih.gov/17092910