Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Beate M, Lichtenberger"'
Autor:
Agnes Forsthuber, Bertram Aschenbrenner, Ana Korosec, Tina Jacob, Karl Annusver, Natalia Krajic, Daria Kholodniuk, Sophie Frech, Shaohua Zhu, Kim Purkhauser, Katharina Lipp, Franziska Werner, Vy Nguyen, Johannes Griss, Wolfgang Bauer, Ana Soler Cardona, Benedikt Weber, Wolfgang Weninger, Bernhard Gesslbauer, Clement Staud, Jakob Nedomansky, Christine Radtke, Stephan N. Wagner, Peter Petzelbauer, Maria Kasper, Beate M. Lichtenberger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Cancer-associated fibroblasts (CAFs) play a key role in cancer progression and treatment outcome. This study dissects the intra-tumoral diversity of CAFs in basal cell carcinoma, squamous cell carcinoma, and melanoma using molecular and spat
Externí odkaz:
https://doaj.org/article/a22a247107aa466393a272561f7fb79c
Autor:
Sophie Frech, Beate M. Lichtenberger
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Epithelial tissues, including the skin, are highly proliferative tissues with the capability to constant renewal and regeneration, a feature that is essential for survival as the skin forms a protective barrier against external insults and water loss
Externí odkaz:
https://doaj.org/article/5066fe5b791e497594bf81fab7239e77
Autor:
Nicole Amberg, Panagiota A. Sotiropoulou, Gerwin Heller, Beate M. Lichtenberger, Martin Holcmann, Bahar Camurdanoglu, Temenuschka Baykuscheva-Gentscheva, Cedric Blanpain, Maria Sibilia
Publikováno v:
iScience, Vol 15, Iss , Pp 243-256 (2019)
Summary: Epidermal growth factor receptor (EGFR) signaling controls skin development and homeostasis in mice and humans, and its deficiency causes severe skin inflammation, which might affect epidermal stem cell behavior. Here, we describe the inflam
Externí odkaz:
https://doaj.org/article/fec4df02adcd448198444c8a11fb38f7
Autor:
Gernot Walko, Samuel Woodhouse, Angela Oliveira Pisco, Emanuel Rognoni, Kifayathullah Liakath-Ali, Beate M. Lichtenberger, Ajay Mishra, Stephanie B. Telerman, Priyalakshmi Viswanathan, Meike Logtenberg, Lisa M. Renz, Giacomo Donati, Sven R. Quist, Fiona M. Watt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Individual human epidermal cells differ in their self-renewal ability. Here the authors perform genome-wide pooled RNAi screens to uncover the molecular basis for this heterogeneity, and identify genes conferring a clonal growth advantage on normal a
Externí odkaz:
https://doaj.org/article/2b9b9d9908ac4a09a7f10f863e934277
Autor:
Agnes Forsthuber, Ana Korosec, Tina Jacob, Bertram Aschenbrenner, Karl Annusver, Sophie Frech, Kim Purkhauser, Natalia Krajic, Katharina Lipp, Franziska Werner, Vy Nguyen, Johannes Griss, Wolfgang Bauer, Ana Soler Cardona, Benedikt Weber, Wolfgang Weninger, Bernhard Gesslbauer, Clement Staud, Jakob Nedomansky, Christine Radtke, Stephan N. Wagner, Peter Petzelbauer, Maria Kasper, Beate M. Lichtenberger
Cancer-associated fibroblasts (CAFs) play a key role in cancer progression and treatment outcome. Here, we elucidate the yet unresolved intra-tumoral CAF variety in three skin cancer types at molecular and spatial single-cell resolution in a large co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e3d6a704b566a37a9d53a8ed31a69cf
https://doi.org/10.1101/2023.05.03.539213
https://doi.org/10.1101/2023.05.03.539213
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The molecular mechanisms regulating skin dermal changes are unclear. Here, the authors show that deletion of Hedgehog (Hh) in the upper dermis alters the response to epidermal Wnt signalling, which, together with changes in extracellular matrix produ
Externí odkaz:
https://doaj.org/article/a2f00ef4034b4d2ea03277e5251ed944
Autor:
Tina Jacob, Karl Annusver, Paulo Czarnewski, Tim Dalessandri, Maria Eleni Kastriti, Chiara Levra Levron, Marja L Mikkola, Michael Rendl, Beate M Lichtenberger, Giacomo Donati, Åsa Björklund, Maria Kasper
SUMMARYA wealth of specialized cell populations within the skin facilitates its hair producing, protective, sensory and thermoregulatory functions, but how the vast cell-type diversity and tissue architecture develops is largely unexplored. Here, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e4ba5e96adf0e9de726f0b35d12c435
https://doi.org/10.1101/2022.12.28.522081
https://doi.org/10.1101/2022.12.28.522081
Autor:
Maria Kasper, Beate M. Lichtenberger
Publikováno v:
Journal of Internal Medicine. 289:614-628
Healthy tissues harbour a surprisingly high number of cells that carry well-known cancer-causing mutations without impacting their physiological function. In recent years, strong evidence accumulated that the immediate environment of mutant cells pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd661dd8cf20e2eb9037ccaf200423d
https://doi.org/10.1111/joim.13177
https://doi.org/10.1111/joim.13177
Autor:
Christine Radtke, Werner Haslik, Vera Vorstandlechner, Lisa Shaw, Polina Kalinina, Beate M. Lichtenberger, Hendrik Jan Ankersmit, Erwin Tschachler, Maria Laggner, Michael Mildner
Publikováno v:
The FASEB Journal. 34:3677-3692
Though skin fibroblasts (FB) are the main cell population within the dermis, the different skin FB subsets are not well characterized and the traditional classification into reticular and papillary FBs has little functional relevance. To fill the gap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8949e0b1e3eb123951b3cf906574f3
https://doi.org/10.1096/fj.201902001rr
https://doi.org/10.1096/fj.201902001rr
Autor:
Sophie Frech, Agnes Forsthuber, Ana Korosec, Katharina Lipp, Viktor Kozumov, Beate M. Lichtenberger
Publikováno v:
The Journal of investigative dermatology. 142(6)
Patients suffering from large scars such as burn victims not only encounter aesthetic challenges but also ongoing itching or pain that substantially deteriorates their quality of life. Skin appendages such as hair follicles rarely regenerate within t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e90b97ebf774c1cf7f105b602538f7
https://pubmed.ncbi.nlm.nih.gov/35027172
https://pubmed.ncbi.nlm.nih.gov/35027172