Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Beate M, Henz"'
Publikováno v:
Experimental Dermatology. 15:643-648
Human mast cells have been shown to release histamine in response to the neuropeptide α-melanocyte-stimulating hormone (alpha-MSH), but it is unknown whether these cells express proopiomelanocortin (POMC) or POMC-derived peptides. We therefore exami
Autor:
Thomas A. Luger, Torsten Zuberbier, Beate M. Henz, Andreas Grützkau, Metin Artuc, Alina Smorodchenko, Markus Böhm
Publikováno v:
Journal of Investigative Dermatology. 126(9):1976-1981
Human mast cells have been shown to release histamine in response to the neuropeptide α-melanocyte-stimulating hormone (α-MSH), but it is unknown whether these cells express proopiomelanocortin (POMC) or POMC-derived peptides. We therefore examined
Publikováno v:
Experimental Dermatology. 15:523-529
The coagulation system is thought to play a pivotal role during the initial phase of wound healing, but mechanisms and cells involved are only partly understood. We have therefore examined human scars for the expression of thrombin, its precursor pro
Autor:
Martin Steinhoff, Beate M. Henz, Stefan W. Schneider, Elena E. Pohl, Corinna Moormann, Georg Varga, Nathalie Vergnolle, Metin Artuc, Thomas A. Luger, Jörg Buddenkotte, Randolf Brehler
Publikováno v:
Journal of Investigative Dermatology. 126:746-755
Proteinase-activated receptor-2 (PAR2) belongs to a new G protein-coupled receptor subfamily activated by serine proteinases. PAR2 has been demonstrated to play a role during inflammation and immune response in different tissues including the skin. W
Publikováno v:
British Journal of Dermatology. 153:887-893
Summary Background Angiotensin AT1 and AT2 receptors are expressed in human skin. Furthermore, AT2 receptors have been reported to be upregulated during tissue repair and remodelling in various noncutaneous human tissues. Objectives Detection of alte
Publikováno v:
Journal of Neuroimmunology. 163:92-101
To resolve the controversy regarding substance P (SP) mediated stimulation of mast cells (MC), we demonstrate that SP triggers histamine release from purified human skin MC (sMC), but contrast to stimulation via FcepsilonRI, does not effect the produ
Publikováno v:
Inflammation Research. 54:113-118
Background: All-trans retinoic acid (ATRA) inhibits IgE synthesis from anti-CD40 plus IL-4 stimulated human B lymphocytes. Objective: To study the underlying mechanisms, we examined here molecules which are known to have an impact on IgE production,
Autor:
Beate M. Henz, Richard Stefaniak, Torsten Zuberbier, Helmut Piazena, Magda Babina, Marc Strathmann, Sven Guhl
Publikováno v:
Journal of Investigative Dermatology. 124:453-456
Ultraviolet (UV) irradiation is an established treatment for inflammatory skin diseases, although the precise mode of action is still unclear. Activating and suppressive effects on mast cell (MC) mediator release have been described. The aim of this
Autor:
Torsten Zuberbier, Renate Franke, Magda Babina, Sven Guhl, S. Böhm, Adrian F. Gombart, Beate M. Henz, L. Kirchhof, Y. Schülke
Publikováno v:
CMLS Cellular and Molecular Life Sciences. 62:214-226
Expression profiles of mRNAs and proteins for various transcription factors were determined for human skin mast cells (sMCs), leukemic HMC-1 MCs, monocytes and granulocytes. By quantitative RT-PCR, sMCs expressed lower levels of c-fos, PU.1, C/EBPalp
Publikováno v:
Experimental Dermatology. 13:520-525
CXCL8 plays a major role in cell recruitment to sites of inflammation. Apart from neutrophils, little is known, however, about the cellular distribution and regulation of CXCL8 receptors in cells involved in acquired and adaptive immune responses. In