Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Beate K. Straub"'
Publikováno v:
OTO Open, Vol 8, Iss 2, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/3b4508326d9e40c2bc4598e50194ef0c
Autor:
Maximiliano L. Cacicedo, Christine Weinl-Tenbruck, Daniel Frank, Sebastian Wirsching, Beate K. Straub, Jana Hauke, Jürgen G. Okun, Nigel Horscroft, Julia B. Hennermann, Fred Zepp, Frédéric Chevessier-Tünnesen, Stephan Gehring
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 294-308 (2022)
Hereditary tyrosinemia type 1 is an inborn error of amino acid metabolism characterized by deficiency of fumarylacetoacetate hydrolase (FAH). Only limited treatment options (e.g., oral nitisinone) are available. Patients must adhere to a strict diet
Externí odkaz:
https://doaj.org/article/c558916830de456c8e082c476d56542c
Autor:
Thomas Griemert, Ekkehard Siegel, Moritz Brandstetter, Beate K. Straub, Andreas Kreft, Peter R. Galle, Martin F. Sprinzl
Publikováno v:
Clinical Case Reports, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract We report about a proctitis and ileitis terminalis, leading to the misdiagnosis of Chron's disease, in a male patient who has sex with men. Molecular multiplex analysis identified Entamoeba histolytica as the underlying cause. We provide dia
Externí odkaz:
https://doaj.org/article/d14fecfa84474d299b8c6a6414b5e915
Autor:
Nadine Gehrke, Marcus A. Wörns, Amrit Mann, Nadine Hövelmeyer, Ari Waisman, Beate K. Straub, Peter R. Galle, Jörn M. Schattenberg
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-12 (2022)
Abstract Acute liver failure (ALF) is a rare entity but exhibits a high mortality. The mechanisms underlying ALF are not completely understood. The present study explored the role of the hepatic B cell leukemia-3 (Bcl-3), a transcriptional regulator
Externí odkaz:
https://doaj.org/article/a7c9f6bc2f78494daefe0132b228da87
Autor:
Emilie Crouchet, Simonetta Bandiera, Naoto Fujiwara, Shen Li, Hussein El Saghire, Mirian Fernández-Vaquero, Tobias Riedl, Xiaochen Sun, Hadassa Hirschfield, Frank Jühling, Shijia Zhu, Natascha Roehlen, Clara Ponsolles, Laura Heydmann, Antonio Saviano, Tongqi Qian, Anu Venkatesh, Joachim Lupberger, Eloi R. Verrier, Mozhdeh Sojoodi, Marine A. Oudot, François H. T. Duong, Ricard Masia, Lan Wei, Christine Thumann, Sarah C. Durand, Victor González-Motos, Danijela Heide, Jenny Hetzer, Shigeki Nakagawa, Atsushi Ono, Won-Min Song, Takaaki Higashi, Roberto Sanchez, Rosa S. Kim, C. Billie Bian, Karun Kiani, Tom Croonenborghs, Aravind Subramanian, Raymond T. Chung, Beate K. Straub, Detlef Schuppan, Maliki Ankavay, Laurence Cocquerel, Evelyne Schaeffer, Nicolas Goossens, Anna P. Koh, Milind Mahajan, Venugopalan D. Nair, Ganesh Gunasekaran, Myron E. Schwartz, Nabeel Bardeesy, Alex K. Shalek, Orit Rozenblatt-Rosen, Aviv Regev, Emanuele Felli, Patrick Pessaux, Kenneth K. Tanabe, Mathias Heikenwälder, Catherine Schuster, Nathalie Pochet, Mirjam B. Zeisel, Bryan C. Fuchs, Yujin Hoshida, Thomas F. Baumert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Drug and target discovery for advanced liver disease are hampered by a lack of suitable models for clinical translation. Here the authors present a human liver cell-based system modeling a clinical prognostic signature allowing to propose nizatidine
Externí odkaz:
https://doaj.org/article/454d7d31ae1e40b7812cd73b90a2e7e3
Autor:
Nadine Gehrke, Lea J. Hofmann, Beate K. Straub, Frank Rühle, Ari Waisman, Peter R. Galle, Jörn M. Schattenberg
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 9, Pp n/a-n/a (2022)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is associated with hepatic as well as systemic insulin resistance even in the absence of type 2 diabetes. The extent and pathways through which hepatic inflammation modulates insulin sensit
Externí odkaz:
https://doaj.org/article/f148ac8f3cbd42df84f68542741c90ac
Autor:
Tiemo S. Gerber, Abbas Agaimy, Arndt Hartmann, Michael Habekost, Wilfried Roth, Albrecht Stenzinger, Peter Schirmacher, Beate K. Straub
Publikováno v:
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-6 (2021)
Abstract Background Undifferentiated carcinoma of the biliary tract are highly aggressive malignancies. In other organs, a subgroup of undifferentiated carcinoma related to SWI/SNF complex–deficiency have been described. Case presentation A 30-year
Externí odkaz:
https://doaj.org/article/fd681c393cdf40ad8a355fded87c5b6a
Autor:
Monserrat Gerardo-Ramírez, Vanessa Giam, Diana Becker, Marco Groth, Nils Hartmann, Helen Morrison, Helen L. May-Simera, Markus P. Radsak, Jens U. Marquardt, Peter R. Galle, Peter Herrlich, Beate K. Straub, Monika Hartmann
Publikováno v:
Cells, Vol 12, Iss 9, p 1257 (2023)
Primary liver cancer is the third leading cause of cancer-related death worldwide. An increasing body of evidence suggests that the Hippo tumor suppressor pathway plays a critical role in restricting cell proliferation and determining cell fate durin
Externí odkaz:
https://doaj.org/article/3004799beb8e45d18efc30d9e611b166
Autor:
Simone Marquard, Stefan Thomann, Sofia M. E. Weiler, Michaela Bissinger, Teresa Lutz, Carsten Sticht, Marcell Tóth, Carolina de la Torre, Norbert Gretz, Beate K. Straub, Jens Marquardt, Peter Schirmacher, Kai Breuhahn
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background Overexpression and nuclear enrichment of the oncogene yes-associated protein (YAP) cause tumor initiation and support tumor progression in human hepatocellular carcinoma (HCC) via cell autonomous mechanisms. However, how YAP expre
Externí odkaz:
https://doaj.org/article/e05943d09de64152a22674ca0e705f2e
Autor:
Fabian Bartsch, Janine Baumgart, Maria Hoppe-Lotichius, Beate K. Straub, Stefan Heinrich, Hauke Lang
Publikováno v:
BMC Surgery, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is often diagnosed in advanced stage. Aim of this study was to analyse the influence of resection margins and tumor distance to the liver capsule on survival and recurrence in a single center
Externí odkaz:
https://doaj.org/article/fc2c54517c8641beb64808451c2f1bff