ADAM15 adds to apoptosis resistance of synovial fibroblasts by modulating focal adhesion kinase signaling

Autor: Beate B, Böhm, Isabell, Freund, Kristin, Krause, Raimund W, Kinne, Harald, Burkhardt

Publikováno v: Arthritis and rheumatism. 65(11)

To study the contribution of ADAM15, a disintegrin metalloproteinase that is up-regulated in the rheumatoid arthritis (RA) synovial membrane, to the characteristic resistance of RA synovial fibroblasts (RASFs) to apoptosis induction by genotoxic stre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8c7d40d79a25658593d08fd0153d5943
https://pubmed.ncbi.nlm.nih.gov/23918525

The role of YAP1 target gene CTGF in the anoikis resistance of rheumatoid arthritis synovial fibroblasts.

Autor: Janczi T; Division of Rheumatology, University Hospital Frankfurt, Goethe University, Frankfurt am Main., Fehrl Y; Division of Rheumatology, University Hospital Frankfurt, Goethe University, Frankfurt am Main., Kinne RW; Experimental Rheumatology Unit, Jena University Hospital, Waldkliniken Eisenberg GmbH, Eisenberg., Böhm B; Division of Rheumatology, University Hospital Frankfurt, Goethe University, Frankfurt am Main., Burkhardt H; Division of Rheumatology, University Hospital Frankfurt, Goethe University, Frankfurt am Main.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP.; Fraunhofer Cluster of Excellence Immune-Mediated Diseases CIMD, Frankfurt am Main, Germany.

Publikováno v: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2023 Feb 01; Vol. 62 (2), pp. 850-860.

Genetic Analysis of MPO Variants in Four Psoriasis Subtypes in Patients from Germany.

Autor: Haskamp S; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Horowitz JS; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Oji V; Department of Dermatology, University of Münster, Münster, Germany., Philipp S; Department of Dermatology, University of Berlin, Berlin, Germany., Sticherling M; Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Schäkel K; Department of Dermatology, University of Heidelberg, Heidelberg, Germany., Schuhmann S; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Prinz JC; Department of Dermatology and Allergology, Ludwig-Maximilian University Munich, Munich, Germany., Burkhardt H; Division of Rheumatology, Goethe University, Frankfurt am Main, Germany; Fraunhofer Project Group Translational Medicine and Pharmacology, IME, Goethe University, Frankfurt am Main, Germany., Behrens F; Division of Rheumatology, Goethe University, Frankfurt am Main, Germany; Fraunhofer Project Group Translational Medicine and Pharmacology, IME, Goethe University, Frankfurt am Main, Germany., Böhm B; Division of Rheumatology, Goethe University, Frankfurt am Main, Germany; Fraunhofer Project Group Translational Medicine and Pharmacology, IME, Goethe University, Frankfurt am Main, Germany., Köhm M; Division of Rheumatology, Goethe University, Frankfurt am Main, Germany; Fraunhofer Project Group Translational Medicine and Pharmacology, IME, Goethe University, Frankfurt am Main, Germany., Rech J; Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Simon D; Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Schett G; Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Morrison K; Department of Dermatology, Førde Sentralsjukehus, Førde, Norway., Gerdes S; Psoriasis Center, Department of Dermatology, University Medical Center Schleswig-Holstein, Kiel, Germany., Assmann G; Department of Internal Medicine I, Jose-Carreras Centrum for Immuno- and Gene Therapy, University of Saarland Medical School, Homburg, Germany., Nimeh A; Department of Rheumatology, Fachklinik Bad Bentheim, Bad Bentheim, Germany., Schuster V; Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany., Jacobi A; Ophthalmology and Dermatology Center, Practice Dr Jacobi, Nuremberg, Germany; Institute for Health Care Research in Dermatology and Nursing, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Weyergraf A; Department of Dermatology, Fachklinik Bad Bentheim, Bad Bentheim, Germany., Reis A; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Uebe S; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Wilsmann-Theis D; Department of Dermatology, University of Bonn, Bonn, Germany., Mößner R; Department of Dermatology, Georg-August-University Göttingen, Göttingen, Germany., Hüffmeier U; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany. Electronic address: Ulrike.Hueffmeier@uk-erlangen.de.

Publikováno v: The Journal of investigative dermatology [J Invest Dermatol] 2021 Aug; Vol. 141 (8), pp. 2079-2083. Date of Electronic Publication: 2021 Feb 17.

Genome-wide association and targeted analysis of copy number variants with psoriatic arthritis in German patients.

Autor: Uebe S; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 10, 91054, Erlangen, Germany., Ehrlicher M; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 10, 91054, Erlangen, Germany., Ekici AB; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 10, 91054, Erlangen, Germany., Behrens F; Division of Rheumatology and IME Fraunhofer Project Group Translational Medicine & Pharmacology, Goethe University, Frankfurt/Main, Germany., Böhm B; Division of Rheumatology and IME Fraunhofer Project Group Translational Medicine & Pharmacology, Goethe University, Frankfurt/Main, Germany., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany., Schurmann C; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany., Jünger M; Clinic of Dermatology, University of Greifswald, Greifswald, Germany., Nauck M; Institute of Clinical Chemistry and Laboratory Medicine, University of Greifswald, Greifswald, Germany., Völzke H; Institute for Community Medicine, University of Greifswald, Greifswald, Germany., Traupe H; Department of Dermatology, University of Münster, Münster, Germany., Krawczak M; Institute for Medical Informatics and Statistics, Christian-Albrechts University Kiel, Kiel, Germany., Burkhardt H; Division of Rheumatology and IME Fraunhofer Project Group Translational Medicine & Pharmacology, Goethe University, Frankfurt/Main, Germany., Reis A; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 10, 91054, Erlangen, Germany., Hüffmeier U; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 10, 91054, Erlangen, Germany. Ulrike.Hueffmeier@uk-erlangen.de.

Publikováno v: BMC medical genetics [BMC Med Genet] 2017 Aug 23; Vol. 18 (1), pp. 92. Date of Electronic Publication: 2017 Aug 23.

Variants in RUNX3 contribute to susceptibility to psoriatic arthritis, exhibiting further common ground with ankylosing spondylitis.

Autor: Apel M; University of Erlangen-Nuremberg, Erlangen, Germany., Uebe S, Bowes J, Giardina E, Korendowych E, Juneblad K, Pasutto F, Ekici AB, McManus R, Ho P, Bruce IN, Ryan AW, Behrens F, Böhm B, Traupe H, Lohmann J, Gieger C, Wichmann HE, Padyukov L, Fitzgerald O, Alenius GM, McHugh NJ, Novelli G, Burkhardt H, Barton A, Reis A, Hüffmeier U

Publikováno v: Arthritis and rheumatism [Arthritis Rheum] 2013 May; Vol. 65 (5), pp. 1224-31.