Immunohistochemical Analysis of Nicotinamide Phosphoribosyltransferase Expression in Gastric and Esophageal Adenocarcinoma (AEG)

Autor: Alexander Arnold, Moritz von Winterfeld, Erika Berg, Michael Hummel, Beate Rau, Felix Krenzien, Ulrike Stein, Christoph Treese

Publikováno v: Gastrointestinal Disorders, Vol 4, Iss 4, Pp 333-340 (2022)

Nicotinamide phosphoribosyltransferase (NAMPT) represents a major component in cellular energy metabolism, which is also crucial for cancer cells that have elevated aerobic glycolysis; moreover, targeting the NAD salvage pathway by inhibition of NAMP

Externí odkaz: https://doaj.org/article/f70026abc1ce4a8bb4803bd4438bba6d

Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models

Autor: Mathias Dahlmann, Guido Gambara, Bernadette Brzezicha, Oliver Popp, Eva Pachmayr, Lena Wedeken, Alina Pflaume, Margarita Mokritzkij, Safak Gül-Klein, Andreas Brandl, Caroline Schweiger-Eisbacher, Philipp Mertins, Jens Hoffmann, Ulrich Keilholz, Wolfgang Walther, Christian Regenbrecht, Beate Rau, Ulrike Stein

Publikováno v: Molecular Cancer, Vol 20, Iss 1, Pp 1-8 (2021)

Externí odkaz: https://doaj.org/article/a513481eefbf44dda742bd021ab5b5bd

Systemic Chemotherapy Including Ramucirumab in Combination With Pressurized Intra-Peritoneal Aerosol Chemotherapy Is a Safe Treatment Option for Peritoneal Metastasis of Gastric Cancer

Autor: Linda Feldbrügge, Felix Gronau, Andreas Brandl, Timo Alexander Auer, Alan Oeff, Peter Thuss-Patience, Johann Pratschke, Beate Rau

Publikováno v: Frontiers in Oncology, Vol 10 (2021)

BackgroundPressurized intraperitoneal aerosol chemotherapy (PIPAC) is a laparoscopic technique for local chemotherapy. It has been used for treatment of peritoneal metastasis of gastric cancer (PM GC) in combination with systemic therapy. VEGFR2 anta

Externí odkaz: https://doaj.org/article/645afa80f76f482eab0cfc675cfff718

European Groundshot—addressing Europe's cancer research challenges: a Lancet Oncology Commission

Autor: Mark Lawler, Lynne Davies, Simon Oberst, Kathy Oliver, Alexander Eggermont, Anna Schmutz, Carlo La Vecchia, Claudia Allemani, Yolande Lievens, Peter Naredi, Tanja Cufer, Ajay Aggarwal, Matti Aapro, Kathi Apostolidis, Anne-Marie Baird, Fatima Cardoso, Andreas Charalambous, Michel P Coleman, Alberto Costa, Mirjam Crul, Csaba L Dégi, Federica Di Nicolantonio, Sema Erdem, Marius Geanta, Jan Geissler, Jacek Jassem, Beata Jagielska, Bengt Jonsson, Daniel Kelly, Olaf Kelm, Teodora Kolarova, Tezer Kutluk, Grant Lewison, Françoise Meunier, Jana Pelouchova, Thierry Philip, Richard Price, Beate Rau, Isabel T Rubio, Peter Selby, Maja Južnič Sotlar, Gilliosa Spurrier-Bernard, Jolanda C van Hoeve, Eduard Vrdoljak, Willien Westerhuis, Urszula Wojciechowska, Richard Sullivan

Publikováno v: Lawler, M, Davies, L, Oberst, S, Oliver, K, Eggermont, A, Schmutz, A, La Vecchia, C, Allemani, C, Lievens, Y, Naredi, P, Cufer, T, Aggarwal, A, Aapro, M, Apostolidis, K, Baird, A-M, Cardoso, F, Charalambous, A, Coleman, M P, Costa, A, Crul, M, Dégi, C L, Di Nicolantonio, F, Erdem, S, Geanta, M, Geissler, J, Jassem, J, Jagielska, B, Jonsson, B, Kelly, D, Kelm, O, Kolarova, T, Kutluk, T, Lewison, G, Meunier, F, Pelouchova, J, Philip, T, Price, R, Rau, B, Rubio, I T, Selby, P, Južnič Sotlar, M, Spurrier-Bernard, G, van Hoeve, J C, Vrdoljak, E, Westerhuis, W, Wojciechowska, U & Sullivan, R 2023, ' European Groundshot-addressing Europe's cancer research challenges : a Lancet Oncology Commission ', Lancet Oncology, vol. 24, no. 1, pp. e11-e56 . https://doi.org/10.1016/S1470-2045(22)00540-X

Cancer research is a crucial pillar for countries to deliver more affordable, higher quality, and more equitable cancer care. Patients treated in research-active hospitals have better outcomes than patients who are not treated in these settings. Howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e07d8fcab1f498ebdd71513b8c10c4d
https://doi.org/10.1016/s1470-2045(22)00540-x

Peritonealkarzinose des Magenkarzinoms

Autor: Eva M. Dobrindt, Safak Gül-Klein, Miguel Enrique Alberto Vilchez, Felix Gronau, Peter Thuss-Patience, Beate Rau

Publikováno v: Die Chirurgie. 93:1133-1138

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::833aa8feaa816b5b18c57ff7475344d5
https://doi.org/10.1007/s00104-022-01699-4