Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Beate, Niesler"'
Autor:
Divya Lairikyengbam, Bernhard Wetterauer, Michael Schmiech, Beate Jahraus, Henning Kirchgessner, Pille Wetterauer, Karina Berschneider, Verena Beier, Beate Niesler, Emre Balta, Yvonne Samstag
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionChronic inflammation is a hallmark of chronic wounds and inflammatory skin diseases. Due to a hyperactive and prolonged inflammation triggered by proinflammatory immune cells, transitioning to the repair and healing phase is halted. T cel
Externí odkaz:
https://doaj.org/article/be58dc0b38004bc4bda47d9dc4bb714e
Autor:
Roman Sakson, Lars Beedgen, Patrick Bernhard, K. Merve Alp, Nicole Lübbehusen, Ralph Röth, Beate Niesler, Marcin Luzarowski, Olga Shevchuk, Matthias P. Mayer, Christian Thiel, Thomas Ruppert
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1191 (2024)
Protein glycosylation is an essential post-translational modification in all domains of life. Its impairment in humans can result in severe diseases named congenital disorders of glycosylation (CDGs). Most of the glycosyltransferases (GTs) responsibl
Externí odkaz:
https://doaj.org/article/dd746080971942469ec99d2e6108f5b4
Publikováno v:
Journal of Health Sciences (2023)
Introduction: The COVID-19 pandemic and the restrictions from routine life habits had a tremendous impact on psychological and physical health of youth. It is known that stress, anxiety and depression can be associated with the development of gastroi
Externí odkaz:
https://doaj.org/article/87f4219bd1cf4df3bbfdc717b7763335
Autor:
Emre Balta, Nina Janzen, Henning Kirchgessner, Vasiliki Toufaki, Christian Orlik, Jie Liang, Divya Lairikyengbam, Hinrich Abken, Beate Niesler, Karin Müller-Decker, Thomas Ruppert, Yvonne Samstag
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Use of chimeric antigen receptor (CAR) T cells to treat B cell lymphoma and leukemia has been remarkably successful. Unfortunately, the therapeutic efficacy of CAR T cells against solid tumors is very limited, with immunosuppression by the pro-oxidat
Externí odkaz:
https://doaj.org/article/f505374223d94351a29b95c1ad222ba5
Autor:
Christian Orlik, Karina M. Berschneider, Beate Jahraus, Beate Niesler, Emre Balta, Knut Schäkel, Jutta Schröder-Braunstein, Maria Margarida Souto-Carneiro, Yvonne Samstag
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In psoriasis and other inflammatory skin diseases, keratinocytes (KCs) secrete chemokines that attract T cells, which, in turn, cause epidermal hyperplasia by secreting proinflammatory cytokines. To date, it remains unclear whether skin-homing T cell
Externí odkaz:
https://doaj.org/article/3a5e0b3e4e6845e285ecc3441afcc20d
Autor:
Manuela Gries, Anne Christmann, Steven Schulte, Maximilian Weyland, Stephanie Rommel, Monika Martin, Marko Baller, Ralph Röth, Stefanie Schmitteckert, Marcus Unger, Yang Liu, Frederik Sommer, Timo Mühlhaus, Michael Schroda, Jean-Pierre Timmermans, Isabel Pintelon, Gudrun A. Rappold, Markus Britschgi, Hilal Lashuel, Michael D. Menger, Matthias W. Laschke, Beate Niesler, Karl-Herbert Schäfer
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-23 (2021)
Abstract Background There is increasing evidence that Parkinson’s disease (PD) might start in the gut, thus involving and compromising also the enteric nervous system (ENS). At the clinical onset of the disease the majority of dopaminergic neurons
Externí odkaz:
https://doaj.org/article/49867127eba049789d3649e16f104dff
Autor:
Amit Kulkarni, Tiago Ferreira, Clemens Bretscher, Annabel Grewenig, Nazim El-Andaloussi, Serena Bonifati, Tiina Marttila, Valérie Palissot, Jubayer A. Hossain, Francisco Azuaje, Hrvoje Miletic, Lars A. R. Ystaas, Anna Golebiewska, Simone P. Niclou, Ralf Roeth, Beate Niesler, Amélie Weiss, Laurent Brino, Antonio Marchini
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Rat H-1 parvovirus (H-1PV) is in clinical development for oncolytic therapy. Here, Kulkarni et al. identify LAMC1 as a modulator of H-1PV cell attachment and entry and find that LAMC1 levels and H-1PV oncolytic activity correlate in 59 tested cancer
Externí odkaz:
https://doaj.org/article/e9d685fa483d413282b0592f44b963bf
Autor:
Linda Hofmann, Tsima Abou Kors, Jasmin Ezić, Beate Niesler, Ralph Röth, Sonja Ludwig, Simon Laban, Patrick J. Schuler, Thomas K. Hoffmann, Cornelia Brunner, Valentin Medyany, Marie-Nicole Theodoraki
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Head and neck squamous cell carcinomas (HNSCC) lack tumor-specific biomarkers. Exosomes from HNSCC patients carry immunomodulatory molecules, and correlate with clinical parameters. We compared miRNA profiles of plasma- and saliva-derived
Externí odkaz:
https://doaj.org/article/f4b07b257ef04856b71e8b242130684a
Autor:
Linda Hofmann, Valentin Medyany, Jasmin Ezić, Ramin Lotfi, Beate Niesler, Ralph Röth, Daphne Engelhardt, Simon Laban, Patrick J. Schuler, Thomas K. Hoffmann, Cornelia Brunner, Edwin K. Jackson, Marie-Nicole Theodoraki
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundExosomes contribute to immunosuppression in head and neck squamous cell carcinoma (HNSCC), a tumor entity which lacks specific tumor biomarkers. Plasma-derived exosomes from HNSCC patients correlate with clinical parameters and have potenti
Externí odkaz:
https://doaj.org/article/b081436aafca40e187dd665805d0efb6
Autor:
Katrin Aslan, Verena Turco, Jens Blobner, Jana K. Sonner, Anna Rita Liuzzi, Nicolás Gonzalo Núñez, Donatella De Feo, Philipp Kickingereder, Manuel Fischer, Ed Green, Ahmed Sadik, Mirco Friedrich, Khwab Sanghvi, Michael Kilian, Frederik Cichon, Lara Wolf, Kristine Jähne, Anna von Landenberg, Lukas Bunse, Felix Sahm, Daniel Schrimpf, Jochen Meyer, Allen Alexander, Gianluca Brugnara, Ralph Röth, Kira Pfleiderer, Beate Niesler, Andreas von Deimling, Christiane Opitz, Michael O. Breckwoldt, Sabine Heiland, Martin Bendszus, Wolfgang Wick, Burkhard Becher, Michael Platten
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Modeling patient-individual resistance to immunotherapy is challenging. Here, the authors use a syngeneic experimental hypermutated orthotopic glioma model to define radiological and biological features that can predict or explain the mechanistic dif
Externí odkaz:
https://doaj.org/article/65441a7f16a24904a9e706ac1ace56b2