Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors.

Autor: Cecilia Csölle, Mária Baranyi, Gabriella Zsilla, Agnes Kittel, Flóra Gölöncsér, Peter Illes, Edit Papp, E Sylvester Vizi, Beáta Sperlágh

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e66547 (2013)

Recent investigations have revealed that the genetic deletion of P2X7 receptors (P2rx7) results in an antidepressant phenotype in mice. However, the link between the deficiency of P2rx7 and changes in behavior has not yet been explored. In the presen

Externí odkaz: https://doaj.org/article/27382327741b467e8afd60bc1910c122

Variation along P2RX7 interacts with early traumas on severity of anxiety suggesting a role for neuroinflammation

Autor: Zsuliet Kristof, Zsofia Gal, Dora Torok, Nora Eszlari, Sara Sutori, Berta Erdelyi-Hamza, Peter Petschner, Beata Sperlagh, Ian M. Anderson, John Francis William Deakin, Gyorgy Bagdy, Gabriella Juhasz, Xenia Gonda

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)

Abstract Emotional stress is a leading risk factor in the development of neuropsychiatric disorders possibly via immune activation. P2X7 receptors promote neuroinflammation, and research suggests a relationship between chromosome region 12q2431, in w

Externí odkaz: https://doaj.org/article/81986f79dbbe4dbd83f4ed8d9fedeb10

Editorial: P2X7 as Common Therapeutic Target in Brain Diseases

Autor: Tobias Engel, Annette Nicke, Jan M. Deussing, Beata Sperlagh, Miguel Diaz-Hernandez

Publikováno v: Frontiers in Molecular Neuroscience, Vol 14 (2021)

Externí odkaz: https://doaj.org/article/cf5f4f249d5746cc8c437b70526a8ec4

P2X7 Receptor-Dependent Layer-Specific Changes in Neuron-Microglia Reactivity in the Prefrontal Cortex of a Phencyclidine Induced Mouse Model of Schizophrenia

Autor: Stefano Calovi, Paula Mut-Arbona, Pál Tod, András Iring, Annette Nicke, Susana Mato, E. Sylvester Vizi, Jan Tønnesen, Beata Sperlagh

Publikováno v: Frontiers in Molecular Neuroscience, Vol 13 (2020)

Background: It has been consistently reported that the deficiency of the adenosine triphosphate (ATP) sensitive purinergic receptor P2X7 (P2X7R) ameliorates symptoms in animal models of brain diseases.Objective: This study aimed to investigate the ro

Externí odkaz: https://doaj.org/article/eff053934d3d4d02970cad39ec5d8bd7

Legacy and Emerging Pollutants in an Urban River Stretch and Effects on the Bacterioplankton Community

Autor: Andrea Visca, Anna Barra Caracciolo, Paola Grenni, Ludovica Rolando, Livia Mariani, Jasmin Rauseo, Francesca Spataro, Katalin Monostory, Beata Sperlagh, Luisa Patrolecco

Publikováno v: Water, Vol 13, Iss 3402, p 3402 (2021)
Water; Volume 13; Issue 23; Pages: 3402
Water (Basel) 13 (2021). doi:10.3390/w13233402
info:cnr-pdr/source/autori:Visca A, Barra Caracciolo A, Grenni P, Rolando L, Mariani L, Rauseo J, Spataro F, Monostory K, Sperlagh B, Patrolecco P/titolo:Legacy and emerging pollutants in an urban river stretch and effects on the bacterioplankton community/doi:10.3390%2Fw13233402/rivista:Water (Basel)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:13

River contamination is due to a chemical mixture of point and diffuse pollution, which can compromise water quality. Polycyclic Aromatic Hydrocarbons (PAHs) and emerging compounds such as pharmaceuticals and antibiotics are frequently found in rivers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38302f5b810404a610a4057fc3054270
https://www.mdpi.com/2073-4441/13/23/3402