Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Beata Olejnicka"'
Autor:
Sabina Janciauskiene, Urszula Lechowicz, Magdalena Pelc, Beata Olejnicka, Joanna Chorostowska-Wynimko
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116618- (2024)
SERPIN (serine proteinase inhibitors) is an acronym for the superfamily of structurally similar proteins found in animals, plants, bacteria, viruses, and archaea. Over 1500 SERPINs are known in nature, while only 37 SERPINs are found in humans, which
Externí odkaz:
https://doaj.org/article/94b5ea99259f4d8682f5fd51e1277ee8
Autor:
Friedemann R. Börner, Urszula Lechowicz, Sabine Wrenger, Beatriz Martinez-Delgado, Beata Olejnicka, Tobias Welte, Joanna Chorostowska-Wynimko, Michael Kiehntopf, Sabina Janciauskiene
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/117cc48c4b524340b17a7f8665722819
Autor:
Mariam Al-Omari, Tareq Al-Omari, Nesreen Batainah, Khaled Al-Qauod, Beata Olejnicka, Sabina Janciauskiene
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background It is widely accepted that chronic inflammatory bowel diseases significantly higher a risk for colorectal cancer development. Among different types of treatments for patients with colon cancer, novel protein-based therapeutic stra
Externí odkaz:
https://doaj.org/article/5505183f9e8a4fc7824095cb9259b409
Autor:
Julia Beimdiek, Sabina Janciauskiene, Sabine Wrenger, Sonja Volland, Adriana Rozy, Jan Fuge, Beata Olejnicka, Isabell Pink, Thomas Illig, Alexander Popov, Joanna Chorostowska, Falk F. R. Buettner, Tobias Welte
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background SARS-CoV-2 infected patients show heterogeneous clinical presentations ranging from mild symptoms to severe respiratory failure and death. Consequently, various markers reflect this wide spectrum of disease presentations. Methods
Externí odkaz:
https://doaj.org/article/15e691f1a242452fa7cc0b2bc025ec12
Autor:
Kokilavani Sivaraman, Paco Pino, Guillaume Raussin, Stephanie Anchisi, Charles Metayer, Nicolas Dagany, Julia Held, Sabine Wrenger, Tobias Welte, Maria J. Wurm, Florian M. Wurm, Beata Olejnicka, Sabina Janciauskiene
Publikováno v:
Microorganisms, Vol 11, Iss 11, p 2683 (2023)
Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we investigated whether spike proteins of SARS-CoV-2 induce LDs in human peripheral blood monon
Externí odkaz:
https://doaj.org/article/db2413774549499d9f185926ebfc3649
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/56597c34da714e258633e573dfe3cf12
Autor:
Sabina Janciauskiene, Srinu Tumpara, Nils Helge Schebb, Falk F. R. Buettner, Malwina Mainka, Kokilavani Sivaraman, Stephan Immenschuh, Veronika Grau, Tobias Welte, Beata Olejnicka
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Human alpha-1-antitrypsin (AAT) encoded by the SERPINA1 gene, is an acute phase glycoprotein that regulates inflammatory responses via both protease inhibitory and non-inhibitory activities. We previously reported that AAT controls ATP-induced IL-1β
Externí odkaz:
https://doaj.org/article/3982131efe1046f8be0af6fdc1b06265
Autor:
Annelot D. Sark, Malin Fromme, Beata Olejnicka, Tobias Welte, Pavel Strnad, Sabina Janciauskiene, Jan Stolk
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 380 (2022)
Alpha-1-Antitrypsin (AAT) is a protein of the SERPINA1 gene. A single amino acid mutation (Lys342Glu) results in an expression of misfolded Z-AAT protein, which has a high propensity to intra- and extra-cellular polymerization. Here, we asked whether
Externí odkaz:
https://doaj.org/article/1e25542dc3674980ab9dbb99cda92b1b
Autor:
Mandy Menzel, Sangeetha Ramu, Jenny Calvén, Beata Olejnicka, Asger Sverrild, Celeste Porsbjerg, Ellen Tufvesson, Leif Bjermer, Hamid Akbarshahi, Lena Uller
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
COPD and asthma exacerbations are commonly triggered by rhinovirus infection. Potentially promoting exacerbations, impaired anti-viral signaling and attenuated viral clearance have been observed in diseased bronchial epithelium. Oxidative stress is a
Externí odkaz:
https://doaj.org/article/b66dcf06e27540a091d84d2a7e57fc42
Autor:
Srinu Tumpara, Anna R. Gründing, Kokilavani Sivaraman, Sabine Wrenger, Beata Olejnicka, Tobias Welte, Maria J. Wurm, Paco Pino, Divor Kiseljak, Florian M. Wurm, Sabina Janciauskiene
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7941 (2021)
For the treatment of severe COVID-19, supplementation with human plasma-purified α-1 antitrypsin (AAT) to patients is currently considered. AAT inhibits host proteases that facilitate viral entry and possesses broad anti-inflammatory and immunomodul
Externí odkaz:
https://doaj.org/article/381b24cc03dd491d94d7b6dacb501463