Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Beata Machnicka"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9098 (2024)
Magnetic Fe3O4 nanoparticles (MNPs) functionalized with (3-aminopropylo)trietoksysilan (APTES) or N-carboxymethylchitosan (CMC) were proposed as nanocarriers of methotrexate (MTX) to target ovarian cancer cell lines. The successful functionalization
Externí odkaz:
https://doaj.org/article/287bd080c5f64278aa40b7eccc5e1f01
Autor:
Dżamila M. Bogusławska, Michał Skulski, Rafał Bartoszewski, Beata Machnicka, Elżbieta Heger, Kazimierz Kuliczkowski, Aleksander F. Sikorski
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-26 (2022)
Abstract Pyrimidine 5′-nucleotidase deficiency is a rare erythrocyte enzymopathy. Here we report two cases of hemolytic anemia in brothers of Polish origin that are associated with a very rare mutation. Heterozygous deletion in the NT5C3A gene (c.4
Externí odkaz:
https://doaj.org/article/4e259a929b2c4adabca9f36134a3b8ab
Autor:
Julia Nowak-Jary, Beata Machnicka
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-30 (2022)
Abstract Magnetic iron oxide nanoparticles (MNPs) have been under intense investigation for at least the last five decades as they show enormous potential for many biomedical applications, such as biomolecule separation, MRI imaging and hyperthermia.
Externí odkaz:
https://doaj.org/article/068e2445ac2a4eb4aa32b70bbc22b16a
Publikováno v:
Micro & Nano Letters, Vol 16, Iss 10, Pp 515-523 (2021)
Abstract Chlorambucil is a nitrogen mustard alkylating agent used for the treatment of various malignant and non‐malignant cancers. The use of the chemotherapeutic is limited by its toxic side effects which precludes the use of optimal doses. It wa
Externí odkaz:
https://doaj.org/article/437d577d8a9d491594026e5ef2a39cb6
Publikováno v:
Cellular & Molecular Biology Letters, Vol 25, Iss 1, Pp 1-18 (2020)
Abstract Background Precise coordination of cytoskeletal components and dynamic control of cell adhesion and migration are required for crucial cell processes such as differentiation and morphogenesis. We investigated the potential involvement of αI
Externí odkaz:
https://doaj.org/article/3c2255451d5241ceae73a65d388a139b
Autor:
Beata Machnicka, Aleksander Czogalla, Dżamila M. Bogusławska, Piotr Stasiak, Aleksander F. Sikorski
Publikováno v:
Life, Vol 13, Iss 1, p 151 (2023)
Previously, we reported a new missense mutation in the ANK1 gene that correlated with the hereditary spherocytosis phenotype. This mutation, resulting in L1340P substitution (HGMD CM149731), likely leads to the changes in the conformation of the anky
Externí odkaz:
https://doaj.org/article/ffeae86e026141fab078f4e0c3974972
Autor:
Dżamila M. Bogusławska, Michał Skulski, Beata Machnicka, Stanisław Potoczek, Sebastian Kraszewski, Kazimierz Kuliczkowski, Aleksander F. Sikorski
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11007 (2021)
Hereditary spherocytosis (HS), the most commonly inherited hemolytic anemia in northern Europeans, comprises a group of diseases whose heterogeneous genetic basis results in a variable clinical presentation. High-throughput genome sequencing methods
Externí odkaz:
https://doaj.org/article/dee4794b2989403bb681eb2ed680c83c
Autor:
Justyna M Meissner, Aleksander F Sikorski, Tomasz Nawara, Jakub Grzesiak, Krzysztof Marycz, Dżamila M Bogusławska, Izabela Michalczyk, Marie-Christine Lecomte, Beata Machnicka
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189545 (2017)
T-lymphocyte activation after antigen presentation to the T-Cell Receptor (TCR) is a critical step in the development of proper immune responses to infection and inflammation. This dynamic process involves reorganization of the actin cytoskeleton and
Externí odkaz:
https://doaj.org/article/18a492e1dbdc4fd4a0c01a65d29d675f
Publikováno v:
Cellular & Molecular Biology Letters, Vol 25, Iss 1, Pp 1-18 (2020)
Cellular & Molecular Biology Letters
Cellular & Molecular Biology Letters
Background Precise coordination of cytoskeletal components and dynamic control of cell adhesion and migration are required for crucial cell processes such as differentiation and morphogenesis. We investigated the potential involvement of αII-spectri
Publikováno v:
Experimental Biology and Medicine. 244:1303-1312
Spectrins are proteins that are responsible for many aspects of cell function and adaptation to changing environments. Primarily the spectrin-based membrane skeleton maintains cell membrane integrity and its mechanical properties, together with the c