Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Beata Lecka‐Czernik"'
Autor:
Sudipta Baroi, Piotr J. Czernik, Mohd Parvez Khan, Joshua Letson, Emily Crowe, Amit Chougule, Patrick R. Griffin, Clifford J. Rosen, Beata Lecka-Czernik
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102000- (2024)
Objective: The skeleton is one of the largest organs in the body, wherein metabolism is integrated with systemic energy metabolism. However, the bioenergetic programming of osteocytes, the most abundant bone cells coordinating bone metabolism, is not
Externí odkaz:
https://doaj.org/article/fd12f41dade74bab8b4e130e40b8ee7d
Autor:
Amit Chougule, Sudipta Baroi, Piotr J. Czernik, Emily Crowe, Mi Ra Chang, Patrick R. Griffin, Beata Lecka-Czernik
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionThe view that bone and energy metabolism are integrated by common regulatory mechanisms is broadly accepted and supported by multiple strands of evidence. This includes the well-characterized role of the PPARγ nuclear receptor, which is
Externí odkaz:
https://doaj.org/article/1271eab095ab49fd80e70e0f7b44a2e0
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
The 6th International Meeting on Bone Marrow Adiposity (BMA) entitled “Marrow Adiposity: Bone, Aging, and Beyond” (BMA2020) was held virtually on September 9th and 10th, 2020. The mission of this meeting was to facilitate communication and collab
Externí odkaz:
https://doaj.org/article/ff58b488cb9141aba520a682d67ae0c7
Autor:
Amit Chougule, Vipula Kolli, Sudipta Baroi, Nabil Ebraheim, Piotr J Czernik, Y Peng Loh, Beata Lecka‐Czernik
Publikováno v:
JBMR Plus, Vol 4, Iss 9, Pp n/a-n/a (2020)
ABSTRACT Bone and energy metabolism are integrated by common regulatory mechanisms. Carboxypeptidase E (CPE), also known as obesity susceptibility protein or neurotrophic factor‐α1, is recognized for its function in processing prohormones, includi
Externí odkaz:
https://doaj.org/article/a6d51828a21b4010acc55afefe998b2d
Autor:
Beata Lecka-Czernik, Lance A. Stechschulte, Piotr J. Czernik, Shermel B. Sherman, Shilong Huang, Amrei Krings
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Marrow adipose tissue (MAT) is unique with respect to origin, metabolism, and function. MAT is characterized with high heterogeneity which correlates with skeletal location and bone metabolism. This fat depot is also highly sensitive to various hormo
Externí odkaz:
https://doaj.org/article/d81f0a3e699f4a93b99f4f1804477719
Autor:
Gouri Ranganathan, Resat Unal, Irina Pokrovskaya, Aiwei Yao-Borengasser, Bounleut Phanavanh, Beata Lecka-Czernik, Neda Rasouli, Philip A. Kern
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 11, Pp 2444-2450 (2006)
Acyl-coenzyme A:diacylglycerol transferase (DGAT), fatty acid synthetase (FAS), and LPL are three enzymes important in adipose tissue triglyceride accumulation. To study the relationship of DGAT1, FAS, and LPL with insulin, we examined adipose mRNA e
Externí odkaz:
https://doaj.org/article/3807b4e138304eff8509eff9db21e0c1
Autor:
Vipula Kolli, Lance A Stechschulte, Abigail R Dowling, Sima Rahman, Piotr J Czernik, Beata Lecka-Czernik
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96323 (2014)
Peroxisome proliferator activated receptor gamma (PPARγ) controls both glucose metabolism and an allocation of marrow mesenchymal stem cells (MSCs) toward osteoblast and adipocyte lineages. Its activity is determined by interaction with a ligand whi
Externí odkaz:
https://doaj.org/article/af179a5352ae4948a481dd6c3308e4fe
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51746 (2012)
Lineage allocation of the marrow mesenchymal stem cells (MSCs) to osteoblasts and adipocytes is dependent on both Wnt signaling and PPARγ2 activity. Activation of PPARγ2, an essential regulator of energy metabolism and insulin sensitivity, stimulat
Externí odkaz:
https://doaj.org/article/d5635239e2f644e28fa86b7b84b5cda8
Autor:
Beata Lecka-Czernik, Larry J. Suva
Publikováno v:
PPAR Research, Vol 2006 (2006)
Bone loss with aging results from attenuated and unbalanced bone turnover that has been associated with a decreased number of bone forming osteoblasts, an increased number of bone resorbing osteoclasts, and an increased number of adipocytes (fat cell
Externí odkaz:
https://doaj.org/article/935c20c63cbf47cba9b0b46d1cc72651
Autor:
Beata Lecka-Czernik
Publikováno v:
PPAR Research, Vol 2006 (2006)
Externí odkaz:
https://doaj.org/article/f7fa2bf98f874fb9b4b1ef072398cd0d