Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Beata Joanna Lehka"'
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-1 (2017)
Externí odkaz:
https://doaj.org/article/a3aeb881fc084e61acfdcbacdc0870be
Autor:
Jay D. Keasling, Marcos Laloux, Michael Krogh Jensen, Tadas Jakočiūnas, Lasse Eggers Pedersen, Emil D. Jensen, Beata Joanna Lehka
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 49, iss 15
Jensen, E D, Laloux, M, Lehka, B J, Pedersen, L E, Jakočiūnas, T, Jensen, M K & Keasling, J D 2021, ' A synthetic RNA-mediated evolution system in yeast ', Nucleic Acids Research, vol. 49, no. 15, e88 . https://doi.org/10.1093/nar/gkab472
Nucleic acids research, vol 49, iss 15
Jensen, E D, Laloux, M, Lehka, B J, Pedersen, L E, Jakočiūnas, T, Jensen, M K & Keasling, J D 2021, ' A synthetic RNA-mediated evolution system in yeast ', Nucleic Acids Research, vol. 49, no. 15, e88 . https://doi.org/10.1093/nar/gkab472
Laboratory evolution is a powerful approach to search for genetic adaptations to new or improved phenotypes, yet either relies on labour-intensive human-guided iterative rounds of mutagenesis and selection, or prolonged adaptation regimes based on na
Autor:
Ernesto Simon, David Fischer, Christophe Folly, Stefan Martens, Michael Naesby, Beata Joanna Lehka, Michael Eichenberger
Publikováno v:
Metabolic Engineering
Dihydrochalcones are plant secondary metabolites comprising molecules of significant commercial interest as antioxidants, antidiabetics, or sweeteners. To date, their heterologous biosynthesis in microorganisms has been achieved only by precursor fee
Autor:
Jie Zhang, Tim Snoek, Michael Krogh Jensen, Kanchana Rueksomtawin Kildegaard, Beata Joanna Lehka, Tobias Justus Goedecke, Irina Borodina, Jay D. Keasling, Mette Kristensen, Solvej Siedler, Mette L. Skjoedt, Arun S. Rajkumar, Dushica Arsovska, Michael Eichenberger
Publikováno v:
Nature chemical biology, vol 12, iss 11
Skjoedt, ML; Snoek, T; Kildegaard, KR; Arsovska, D; Eichenberger, M; Goedecke, TJ; et al.(2016). Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast. Nature Chemical Biology, 12(11), 951-958. doi: 10.1038/nchembio.2177. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6mm0t12g
Skjoedt, ML; Snoek, T; Kildegaard, KR; Arsovska, D; Eichenberger, M; Goedecke, TJ; et al.(2016). Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast. Nature Chemical Biology, 12(11), 951-958. doi: 10.1038/nchembio.2177. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6mm0t12g
© 2016 Nature America, Inc. All rights reserved. Whole-cell biocatalysts have proven a tractable path toward sustainable production of bulk and fine chemicals. Yet the screening of libraries of cellular designs to identify best-performing biocatalys
Autor:
Jane Dannow Dyekjaer, Nicolaas Buijs, Katherina Garcia Vanegas, Ernesto Simon, Håvard Jenssen, Niels Bjerg Jensen, Michael Eichenberger, Beata Joanna Lehka, Michael Naesby, Walden E. Bjørn-Yoshimoto
Publikováno v:
Lehka, B J, Eichenberger, M, Bjorn-Yoshimoto, W E, Garcia Vanegas, K, Buijs, N A, Jensen, N B, Dyekaejr, J D, Jenssen, H, Simon, E & Naesby, M 2016, ' Improving heterologous production of phenylpropanoids in Saccharomyces cerevisiae by tackling an unwanted side reaction of Tsc13, an endogenous double-bond reductase ', FEMS Yeast Research, vol. 17, no. 1, fox004 . https://doi.org/10.1093/femsyr/fox004
FEMS Yeast Research
FEMS Yeast Research
Phenylpropanoids, such as flavonoids and stilbenoids, are of great commercial interest, and their production in Saccharomyces cerevisiae is a very promising strategy. However, to achieve commercially viable production, each step of the process must b
Publikováno v:
Garcia Vanegas, K, Lehka, B J & Mortensen, U H 2017, ' SWITCH: a dynamic CRISPR tool for genome engineering and metabolic pathway control for cell factory construction in Saccharomyces cerevisiae ', Microbial Cell Factories, vol. 16, no. 25 . https://doi.org/10.1186/s12934-017-0632-x
BackgroundThe yeast Saccharomyces cerevisiae is increasingly used as a cell factory. However, cell factory construction time is a major obstacle towards using yeast for bio-production. Hence, tools to speed up cell factory construction are desirable.