Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Beata, Sieklucka"'
Autor:
Julia Nowowiejska, Anna Baran, Anna Pryczynicz, Justyna Hermanowicz, Beata Sieklucka, Dariusz Pawlak, Iwona Flisiak
Publikováno v:
Dermatology Practical & Conceptual, Vol 14, Iss 3 (2024)
Introduction: Psoriasis is a frequent and incurable skin disease that is an important issue in contemporary dermatology, whereas its pathogenesis is still uncertain. Gasdermin A (GSDMA) is a member of the gasdermin protein family that enables pore fo
Externí odkaz:
https://doaj.org/article/fc88d5e49c8b42afa218f2550a29d170
Autor:
Malgorzata Karbowska, Krystyna Pawlak, Beata Sieklucka, Tomasz Domaniewski, Urszula Lebkowska, Radoslaw Zawadzki, Dariusz Pawlak
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Indoxyl sulfate (IS), an agonist of aryl hydrocarbon receptors (AhR), can accumulate in patients with chronic kidney disease, but its direct effect on bone is not clear. The present study investigated the effect of chronic exposure to low (1
Externí odkaz:
https://doaj.org/article/a814811de0df473eb93fd94bb71e42ad
Autor:
Julia Nowowiejska, Anna Baran, Anna Pryczynicz, Justyna Magdalena Hermanowicz, Beata Sieklucka, Dariusz Pawlak, Iwona Flisiak
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Psoriasis is one of the most common skin diseases and a crucial issue to manage in contemporary dermatology. The search for the details of its pathogenesis, markers and treatment is continuously ongoing. Our aim was to investigate the role of gasderm
Externí odkaz:
https://doaj.org/article/13b41c2281d7480eb85a074af9c476b1
Autor:
Julia Nowowiejska, Anna Baran, Justyna M. Hermanowicz, Beata Sieklucka, Dariusz Pawlak, Iwona Flisiak
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 10, Pp 2217-2227 (2023)
Abstract Introduction Psoriasis, one of the most frequent dermatoses, strongly associated with metabolic disorders which increase patients’ comorbidity and mortality. Hence, it is essential to look for markers of such complications. Our aim was to
Externí odkaz:
https://doaj.org/article/ef45b087ed824a9c958d01b5cdd5fb48
Autor:
Julia Nowowiejska, Anna Baran, Justyna Magdalena Hermanowicz, Beata Sieklucka, Dariusz Pawlak, Iwona Flisiak
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1472 (2023)
Psoriasis is a complex disease that nowadays is considered not only a dermatosis but a kind of systemic disorder associated with many accompanying diseases. Metabolic complications leading to cardiovascular incidences are the cause of increased morta
Externí odkaz:
https://doaj.org/article/4d7548d0811d4a7bb3860bc17639d868
Autor:
Julia Nowowiejska, Anna Baran, Anna Pryczynicz, Justyna Magdalena Hermanowicz, Beata Sieklucka, Dariusz Pawlak, Iwona Flisiak
Publikováno v:
Cells, Vol 12, Iss 17, p 2149 (2023)
Psoriasis is a frequent and incurable skin disease whose pathogenesis is still not fully understood. It is characterized by immune disturbances leading to hyperproliferation and improper differentiation of keratinocytes. Gasdermin E (GSDME) is a prot
Externí odkaz:
https://doaj.org/article/9438e92f4cc2412ead348ec8b4aa2b1c
Autor:
Julia Nowowiejska, Anna Baran, Justyna Magdalena Hermanowicz, Anna Pryczynicz, Beata Sieklucka, Dariusz Pawlak, Iwona Flisiak
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13047 (2023)
Psoriasis is an important issue in daily dermatological practice. Not only is it an aesthetic defect but it is also a matter of decreased life quality and economic burden. However frequent, the pathogenesis of psoriasis remains uncertain despite nume
Externí odkaz:
https://doaj.org/article/14b63d24d5e24a5f953c7d5d747227d0
Autor:
Justyna Magdalena Hermanowicz, Anna Szymanowska, Beata Sieklucka, Robert Czarnomysy, Krystyna Pawlak, Anna Bielawska, Krzysztof Bielawski, Joanna Kalafut, Alicja Przybyszewska, Arkadiusz Surazynski, Adolfo Rivero-Muller, Mariusz Mojzych, Dariusz Pawlak
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 535-548 (2021)
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in men and in women. The impact of the new pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulphonamide (MM-129) was evaluated against human colon cancer in vitro and in zebra
Externí odkaz:
https://doaj.org/article/16356bbb3b0d4b34b72198eeb4905e86
Autor:
Dariusz Rozkiewicz, Justyna Magdalena Hermanowicz, Anna Tankiewicz-Kwedlo, Beata Sieklucka, Krystyna Pawlak, Robert Czarnomysy, Krzysztof Bielawski, Arkadiusz Surazynski, Joanna Kalafut, Alicja Przybyszewska, Mariusz Koda, Katarzyna Jakubowska, Adolfo Rivero-Muller, Dariusz Pawlak
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1697-1711 (2020)
Recombinant human erythropoietin (Epo) is an effective and convenient treatment for cancer-related anaemia. In our study for the first time, we evaluated the effect of simultaneous use of Epo and Bruton’s tyrosine kinase (BTK) inhibitor LFM-A13 on
Externí odkaz:
https://doaj.org/article/418377d1f791473ea76404dcb6f5a02c
Publikováno v:
Nutrients, Vol 14, Iss 19, p 4082 (2022)
Chronic kidney disease (CKD) commonly occurs with vitamin K (VK) deficiency and impaired bone mineralization. However, there are no data explaining the metabolism of endogenous VK and its role in bone mineralization in CKD. In this study, we measured
Externí odkaz:
https://doaj.org/article/ba9f243af8bb49578b9b694a161890d1