Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Beat Fierz"'
Autor:
Harsh Nagpal, Ahmad Ali-Ahmad, Yasuhiro Hirano, Wei Cai, Mario Halic, Tatsuo Fukagawa, Nikolina Sekulić, Beat Fierz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Centromeres are epigenetically defined via the presence of the histone H3 variant CENP-A. Contacting CENP-A nucleosomes, the constitutive centromere associated network (CCAN) and the kinetochore assemble, connecting the centromere to spindle
Externí odkaz:
https://doaj.org/article/61ccb81d61444f478e9b161118cbf73a
Autor:
Beat Fierz
Publikováno v:
CHIMIA, Vol 76, Iss 10 (2022)
Externí odkaz:
https://doaj.org/article/2597b7aa33954345bfb033eb0f0ed7d8
Autor:
Beat Fierz
Publikováno v:
CHIMIA, Vol 75, Iss 6, Pp 484-488 (2021)
Epigenetics research focuses on the study of heritable gene regulatory mechanisms that do not involve changes of the DNA sequence. Such mechanisms include post-translational modifications of histone proteins that organize the genome in the nucleus in
Externí odkaz:
https://doaj.org/article/6657b7f80a7f4d4eb301cceef4b7e825
Autor:
Alessandro Stirpe, Nora Guidotti, Sarah J Northall, Sinan Kilic, Alexandre Hainard, Oscar Vadas, Beat Fierz, Thomas Schalch
Publikováno v:
eLife, Vol 10 (2021)
The SUV39 class of methyltransferase enzymes deposits histone H3 lysine 9 di- and trimethylation (H3K9me2/3), the hallmark of constitutive heterochromatin. How these enzymes are regulated to mark specific genomic regions as heterochromatic is poorly
Externí odkaz:
https://doaj.org/article/9fce28dce8f64cc388467c3c13dde5f4
Autor:
Naemi Luithle, Jelmi uit de Bos, Ruud Hovius, Daria Maslennikova, Renard TM Lewis, Rosemarie Ungricht, Beat Fierz, Ulrike Kutay
Publikováno v:
eLife, Vol 9 (2020)
The inner nuclear membrane is functionalized by diverse transmembrane proteins that associate with nuclear lamins and/or chromatin. When cells enter mitosis, membrane-chromatin contacts must be broken to allow for proper chromosome segregation; yet h
Externí odkaz:
https://doaj.org/article/679c993e628941b28e46150ce42c759e
Autor:
Sinan Kilic, Suren Felekyan, Olga Doroshenko, Iuliia Boichenko, Mykola Dimura, Hayk Vardanyan, Louise C. Bryan, Gaurav Arya, Claus A. M. Seidel, Beat Fierz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Chromatin fibers undergo continuous structural rearrangements but their dynamic architecture is poorly understood. Here, the authors use single-molecule FRET to determine the structural states and interconversion kinetics of chromatin fibers, monitor
Externí odkaz:
https://doaj.org/article/55aef55e51994ac3bbeb3ecc70bf2209
Autor:
Andrea Callegari, Christian Sieben, Alexander Benke, David M Suter, Beat Fierz, Davide Mazza, Suliana Manley
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007891 (2019)
Transcription factors (TFs) regulate gene expression in both prokaryotes and eukaryotes by recognizing and binding to specific DNA promoter sequences. In higher eukaryotes, it remains unclear how the duration of TF binding to DNA relates to downstrea
Externí odkaz:
https://doaj.org/article/92ec5a11b7a64dc6ae9f609a40622c85
Autor:
Oliver Hantschel, Beat Fierz
Publikováno v:
CHIMIA, Vol 70, Iss 3 (2016)
Externí odkaz:
https://doaj.org/article/528f7df8b37a44aaa300ec05ea6f2da2
Publikováno v:
CHIMIA, Vol 69, Iss 10 (2015)
Externí odkaz:
https://doaj.org/article/3ecea584b82d4a0bb743792e7eb8d7d1
Publikováno v:
ACS Chemical Biology, 18 (5)
ACS Chemical Biology
ACS Chemical Biology
Chromatin is spatially organized into functional states that are defined by both the presence of specific histone post-translational modifications (PTMs) and a defined set of chromatin-associated “reader” proteins. Different models for the underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fbccbdcb0b3d2a5c69e25273d46752
https://hdl.handle.net/20.500.11850/620189
https://hdl.handle.net/20.500.11850/620189
