Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Bea Pauwels"'
Autor:
Ridha Limame, An Wouters, Bea Pauwels, Erik Fransen, Marc Peeters, Filip Lardon, Olivier De Wever, Patrick Pauwels
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46536 (2012)
BackgroundCell viability and motility comprise ubiquitous mechanisms involved in a variety of (patho)biological processes including cancer. We report a technical comparative analysis of the novel impedance-based xCELLigence Real-Time Cell Analysis de
Externí odkaz:
https://doaj.org/article/078390a688b14c2da2bad064c1ba0273
Autor:
Sylvia Dewilde, Jan B. Vermorken, Johan Ides, Paul Meijnders, An Wouters, Greet G. O. Pattyn, Filip Lardon, Bea Pauwels, Hilde A. J. Lambrechts, Marc Baay
Publikováno v:
Cancer letters
Hypoxic tumour regions often contain viable cells that are more resistant to chemotherapy and/or radiotherapy, making it of key importance to analyse new combination treatments under both normoxic and hypoxic conditions. In this study, the impact of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b145f6f9615ddc68ecd63adfdbee73
https://doi.org/10.1016/j.canlet.2009.05.026
https://doi.org/10.1016/j.canlet.2009.05.026
Autor:
Greet G. O. Pattyn, Jan B. Vermorken, Bea Pauwels, S. Van Laere, An Wouters, Paul Meijnders, Johan Ides, Filip Lardon, Hilde A. J. Lambrechts, Katrien Vermeulen
Publikováno v:
British Journal of Cancer
The British journal of cancer
The British journal of cancer
Background: The aim of this study was to evaluate the radiosensitising effect of gemcitabine, in terms of cell-cycle progression, induction of apoptosis, and to investigate the molecular events regulating apoptosis. Methods: Tumour cells were treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b929c0570bc1a7633f8c017d316a06d
https://doi.org/10.1038/sj.bjc.6605145
https://doi.org/10.1038/sj.bjc.6605145
Autor:
Filip Lardon, Bea Pauwels, Cindy Simoens, Fabienne Breillout, Greet G. O. Pattyn, Jan B. Vermorken, Hilde A. J. Lambrechts
Publikováno v:
Cancer chemotherapy and pharmacology
Vinflunine is an innovative microtubule inhibitor belonging to the vinca alkaloid class that possesses radiosensitising properties, which could lead to promising activity in chemoradiation studies in the clinic. In the current study, different incuba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f16917416287d65cb363e6ec328d3c
https://doi.org/10.1007/s00280-007-0587-4
https://doi.org/10.1007/s00280-007-0587-4
Autor:
Hilde A. J. Lambrechts, Christel De Pooter, Filip Lardon, Annelies E. C. Korst, Jan B. Vermorken, Greet G. O. Pattyn, Bea Pauwels
Publikováno v:
Cancer chemotherapy and pharmacology
Purpose: Gemcitabine is an active antitumour agent with radiosensitising properties. Gemcitabine is rapidly metabolised, intracellularly as well as extracellularly, by deoxycytidine deaminase to difluorodeoxyuridine (dFdU), a compound with little ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60ea8d4feaf30928c4870213a753fd7
https://doi.org/10.1007/s00280-005-0158-5
https://doi.org/10.1007/s00280-005-0158-5
Autor:
Godehard Friedel, Gunther Guetens, Ernst A. de Bruijn, Sander Romijn, Jeroen M.H. Hendriks, Bea Pauwels, Paul Van Schil, Bart P. van Putte
Publikováno v:
Journal of Surgical Research. 109:118-122
Background. Toxicity and pharmacokinetics of gemcitabine (GCB) were evaluated in a rat model of isolated lung perfusion (ILuP) and compared to intravenous (iv) infusion. Materials and methods. CC531S adenocarcinoma cells were incubated in vitro for 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7626347957af12da954eb423469bac11
https://doi.org/10.1016/s0022-4804(02)00063-x
https://doi.org/10.1016/s0022-4804(02)00063-x
Autor:
Kaye J. Williams, Kris Laukens, Dirk Van Gestel, Filip Lardon, Danielle Van den Weyngaert, Bea Pauwels, Patrick Pauwels, Trung Nghia Vu, Nathalie Burrows, Vanessa Deschoolmeester, Marc Peeters, Jan B. Vermorken, An Wouters, Paul Meijnders, Marc Baay
Publikováno v:
BMC cancer, 14
BMC Cancer
BMC cancer
BMC Cancer
BMC cancer
Regions within solid tumours often experience oxygen deprivation, which is associated with resistance to chemotherapy and irradiation. The aim of this study was to evaluate the radiosensitising effect of gemcitabine and its main metabolite dFdU under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e769b6786a8cc9ecf09fc68a25096ae
https://doi.org/10.1186/1471-2407-14-594
https://doi.org/10.1186/1471-2407-14-594
Autor:
Bea Pauwels, Marc Peeters, Ridha Limame, Filip Lardon, An Wouters, Erik Fransen, Olivier De Wever, Patrick Pauwels
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e46536 (2012)
PLOS ONE
PLoS ONE, Vol 7, Iss 10, p e46536 (2012)
PLOS ONE
BackgroundCell viability and motility comprise ubiquitous mechanisms involved in a variety of (patho)biological processes including cancer. We report a technical comparative analysis of the novel impedance-based xCELLigence Real-Time Cell Analysis de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9219e8266adcfd6f8a5c380fc1053c26
https://pubmed.ncbi.nlm.nih.gov/23094027
https://pubmed.ncbi.nlm.nih.gov/23094027
Autor:
Bea Pauwels, Carolien Boeckx, Pol Specenier, Krzysztof Lukaszuk, Marc Baay, An Wouters, Filip Lardon, Vanessa Deschoolmeester, Marc Peeters, Jan B. Vermorken, Patrick Pauwels
Publikováno v:
The American journal of surgical pathology: diagnostic molecular pathology: part B
Background: Formalin-fixed paraffin-embedded (FFPE) tissue is the most common tissue specimen widely available. Moreover, long clinical follow-up is on hand. Therefore, FFPE material is a precious source of material for identifying predictive and/or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadb72e8b3562a7fd2761aabbabe5c78
https://pubmed.ncbi.nlm.nih.gov/22089347
https://pubmed.ncbi.nlm.nih.gov/22089347
Autor:
Greet G. O. Pattyn, Bea Pauwels, Hilde A. J. Lambrechts, Paul Meijnders, Filip Lardon, Marc Baay, Jan B. Vermorken, An Wouters
Publikováno v:
BMC cancer
BMC Cancer, Vol 10, Iss 1, p 441 (2010)
BMC Cancer
BMC Cancer, Vol 10, Iss 1, p 441 (2010)
BMC Cancer
Background Based on their different mechanisms of action, non-overlapping side effects and radiosensitising potential, combining the antimetabolites pemetrexed (multitargeted antifolate, MTA) and gemcitabine (2',2'-difluorodeoxycytidine, dFdC) with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248a4b989ccde912fca80fb0fa83f1de
https://doi.org/10.1186/1471-2407-10-441
https://doi.org/10.1186/1471-2407-10-441