Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Beáta, Lizák"'
Autor:
Beáta Lizák, Julia Birk, Melinda Zana, Gergely Kosztyi, Denise V. Kratschmar, Alex Odermatt, Richard Zimmermann, Miklós Geiszt, Christian Appenzeller-Herzog, Gábor Bánhegyi
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background The lumen of the endoplasmic reticulum (ER) acts as a cellular Ca2+ store and a site for oxidative protein folding, which is controlled by the reduced glutathione (GSH) and glutathione-disulfide (GSSG) redox pair. Although depleti
Externí odkaz:
https://doaj.org/article/6e96e7b7282a4f3fb5aef956daf86129
Publikováno v:
Bio Protoc
The production of reactive oxygen species (ROS) and endoplasmic reticulum (ER) stress are tightly linked. The generation of ROS can be both the cause and a consequence of ER stress pathways, and an increasing number of human diseases are characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3369b3b0751f689afeafda00ee355fd
https://pubmed.ncbi.nlm.nih.gov/34327273
https://pubmed.ncbi.nlm.nih.gov/34327273
Autor:
Melinda Zana, Richard Zimmermann, Julia Birk, Beáta Lizák, Denise V. Kratschmar, Miklós Geiszt, Christian Appenzeller-Herzog, Gergely Kosztyi, Gábor Bánhegyi, Alex Odermatt
Publikováno v:
BMC Biology
BMC Biology, Vol 18, Iss 1, Pp 1-16 (2020)
BMC Biology, Vol 18, Iss 1, Pp 1-16 (2020)
Background The lumen of the endoplasmic reticulum (ER) acts as a cellular Ca2+ store and a site for oxidative protein folding, which is controlled by the reduced glutathione (GSH) and glutathione-disulfide (GSSG) redox pair. Although depletion of lum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930f18a710e3e067e628a3b0e210b48a
http://europepmc.org/articles/PMC7043043
http://europepmc.org/articles/PMC7043043
Autor:
Paola Marcolongo, Kyu Sung Choi, Gábor Bánhegyi, András Szarka, Angelo Benedetti, Beáta Lizák, Yejin Kim, Csilla E. Németh, Éva Margittai
Publikováno v:
International Journal of Molecular Sciences
Glucose is a basic nutrient in most of the creatures; its transport through biological membranes is an absolute requirement of life. This role is fulfilled by glucose transporters, mediating the transport of glucose by facilitated diffusion or by sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bba39427e7e4d0f05bf20984f08efbe
https://pubmed.ncbi.nlm.nih.gov/31771288
https://pubmed.ncbi.nlm.nih.gov/31771288
Publikováno v:
International Journal of Molecular Sciences; Volume 18; Issue 1; Pages: 58
International Journal of Molecular Sciences, Vol 18, Iss 1, p 58 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 1, p 58 (2017)
International Journal of Molecular Sciences
Accumulation of misfolded/unfolded proteins in the endoplasmic reticulum (ER) leads to the activation of three branches (Protein kinase (RNA)-like endoplasmic reticulum kinase [PERK], Inositol requiring protein 1 [IRE-1] and Activating trascription f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3da5017dbe9466ea5feeb03a09fa195
Publikováno v:
Current Pharmaceutical Biotechnology. 15:1019-1025
Presenilin (PS) was identified in screens for mutations causing the early onset forms of familial Alzheimer's disease (FAD) in 1995. As catalytic units of the γ-secretase complex, presenilins participate in the processing of amyloid beta protein (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e87ae1ad59bc4385eb339368dc19f08
https://doi.org/10.2174/1389201015666141122204139
https://doi.org/10.2174/1389201015666141122204139
Publikováno v:
Computational Molecular Bioscience. :28-34
Each eukaryotic cell of multicellular organisms must be able to maintain its integrity by sensing both external and internal stimuli. The primary goal of the generated response mechanism is to drive back the system to the former or to a new homeostat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad0e8c1c6057c6faf3a33fcde9a6b5b4
https://doi.org/10.4236/cmb.2014.41003
https://doi.org/10.4236/cmb.2014.41003
Autor:
Vincenzo Sorrentino, Barbara Gava, Angelo Benedetti, Miklós Csala, Silvia Senesi, Beáta Lizák, Gábor Bánhegyi, Rosella Fulceri, Paola Marcolongo, Éva Margittai
Publikováno v:
Biochemical Pharmacology. 76:382-390
Preadipocyte differentiation is greatly affected by prereceptorial glucocorticoid activation catalyzed by 11β-hydroxysteroid dehydrogenase type 1 in the lumen of the endoplasmic reticulum. The role of the local NADPH pool in this process was investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3555b2411efb9c6bbfca76955a0af053
https://doi.org/10.1016/j.bcp.2008.05.027
https://doi.org/10.1016/j.bcp.2008.05.027
Publikováno v:
Molecular Membrane Biology. 25:95-101
Transmembrane fluxes are major determinants of several enzyme activities localized in the luminal compartment of the endoplasmic reticulum (ER). Although a large number of metabolites were shown to be transported across the ER membrane, only a few tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0db6ada4030542948d1433a35b7ad3
https://doi.org/10.1080/09687680701670481
https://doi.org/10.1080/09687680701670481
Autor:
Beáta Lizák, Peter Csermely, Éva Margittai, Angelo Benedetti, József Mandl, Eszter Papp, Gábor Bánhegyi, Miklós Csala, Ibolya Czegle, Simona Piccirella, Rosella Fulceri, Silvia Senesi
Publikováno v:
Journal of Biological Chemistry. 281:4671-4677
The redox state of the intraluminal pyridine nucleotide pool was investigated in rat liver microsomal vesicles. The vesicles showed cortisone reductase activity in the absence of added reductants, which was dependent on the integrity of the membrane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c73eee77577d33b3054fdf1abff658
https://doi.org/10.1074/jbc.m509406200
https://doi.org/10.1074/jbc.m509406200