Bcs1, a novel target for fungicide

Autor: Jingyu Zhan, Di Xia

Publikováno v: Frontiers in Chemistry, Vol 11 (2023)

The mitochondrial respiratory chain has long been a primary target for the development of fungicides for its indispensable role in various cellular functions including energy metabolism. Over the years, a wide range of natural and synthetic fungicide

Externí odkaz: https://doaj.org/article/5991de96d34e45be91034e321616c355

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A novel mechanism involved in the coupling of mitochondrial biogenesis to oxidative phosphorylation

Autor: Jelena Ostojić, Jean-Paul di Rago, Geneviève Dujardin

Publikováno v: Microbial Cell, Vol 1, Iss 1, Pp 43-45 (2014)

Mitochondria are essential organelles that are central to a multitude of cellular processes, including oxidative phosphorylation (OXPHOS), which produces most of the ATP in animal cells. Thus it is important to understand not only the mechanisms and

Externí odkaz: https://doaj.org/article/04c93f2418444e32ad8f4509278b38d5

Artemisinin and its derivatives target mitochondrial c-type cytochromes in yeast and human cells

Autor: Cristina Panozzo, Jelena Ostojic, Marc Blondel, Anaïs Laleve, Abdoulaye Sissoko, Déborah Tribouillard-Tanvier, Jérôme Clain, Alexa Bourand-Plantefol, David Cornu, Geneviève Dujardin, Nathalie Bonnefoy, Brigitte Meunier, Romain Duval, Angélique Burg, Inge Kühl

Publikováno v: Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, 2020, pp.118661. ⟨10.1016/j.bbamcr.2020.118661⟩
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2020, pp.118661. ⟨10.1016/j.bbamcr.2020.118661⟩

anais.laleve@inrae.frgenevieve.dujardin@i2bc.paris-saclay.fr; International audience; Artemisinin and its derivatives kill malaria parasites and inhibit the proliferation of cancer cells. In both processes, heme was shown to play a key role in artemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910b411ff7d85e17ba4e73a62518f80c
https://hal.science/hal-02464287/document

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