Smoldering multiple myeloma: prevalence and current evidence guiding treatment decisions

Autor: Blum A, Bazou D, O'Gorman P

Publikováno v: Blood and Lymphatic Cancer: Targets and Therapy, Vol Volume 8, Pp 21-31 (2018)

Agnieszka Blum, Despina Bazou, Peter O’Gorman Department of Hematology, Mater Misericordiae University Hospital, Dublin, UK Abstract: Smoldering multiple myeloma (SMM) is an asymptomatic plasma cell proliferative disorder associated with risk of pr

Externí odkaz: https://doaj.org/article/5ba3e1320cb1480eaabafb1d21a824b7

Multiple Myeloma Derived Extracellular Vesicle Uptake by Monocyte Cells Stimulates IL-6 and MMP-9 Secretion and Promotes Cancer Cell Migration and Proliferation.

Autor: Sheridan R; School of Biomolecular and Biomedical Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland., Brennan K; School of Biomolecular and Biomedical Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland., Bazou D; Department of Haematology, Mater Misericordiae University Hospital, D07 R2WY Dublin, Ireland.; School of Medicine, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland., O'Gorman P; Department of Haematology, Mater Misericordiae University Hospital, D07 R2WY Dublin, Ireland., Matallanas D; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland., Mc Gee MM; School of Biomolecular and Biomedical Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.

Publikováno v: Cancers [Cancers (Basel)] 2024 Feb 29; Vol. 16 (5). Date of Electronic Publication: 2024 Feb 29.

Bleeding and Thrombosis in Multiple Myeloma: Platelets as Key Players during Cell Interactions and Potential Use as Drug Delivery Systems.

Autor: Kulkarni A; The School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, The University of Dublin, D02 PN40 Dublin, Ireland., Bazou D; School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland., Santos-Martinez MJ; The School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, The University of Dublin, D02 PN40 Dublin, Ireland.; School of Medicine, Trinity College Dublin, D02 R590 Dublin, Ireland.; Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 R590 Dublin, Ireland.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 01; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 01.

Proteomic and Metabolomic Analysis of Bone Marrow and Plasma from Patients with Extramedullary Multiple Myeloma Identifies Distinct Protein and Metabolite Signatures.

Autor: Dunphy K; Department of Biology, Maynooth University, W23 F2K8 Kildare, Ireland., Bazou D; Department of Haematology, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland., Henry M; National Institute for Cellular Biotechnology, Dublin City University, D09 NR58 Dublin, Ireland., Meleady P; National Institute for Cellular Biotechnology, Dublin City University, D09 NR58 Dublin, Ireland., Miettinen JJ; Institute for Molecular Medicine Finland-FIMM, HiLIFE-Helsinki Institute of Life Science, iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, 00290 Helsinki, Finland., Heckman CA; Institute for Molecular Medicine Finland-FIMM, HiLIFE-Helsinki Institute of Life Science, iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, 00290 Helsinki, Finland., Dowling P; Department of Biology, Maynooth University, W23 F2K8 Kildare, Ireland., O'Gorman P; Department of Haematology, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland.

Publikováno v: Cancers [Cancers (Basel)] 2023 Jul 25; Vol. 15 (15). Date of Electronic Publication: 2023 Jul 25.

Inhibition of CXCR4 Enhances the Efficacy of Radiotherapy in Metastatic Prostate Cancer Models.

Autor: Gupta N; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Ochiai H; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Hoshino Y; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Klein S; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Zustin J; Institute of Pathology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany., Ramjiawan RR; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Kitahara S; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Maimon N; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Bazou D; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Chiang S; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Li S; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Schanne DH; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Jain RK; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Munn LL; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Huang P; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Kozin SV; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Duda DG; Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Publikováno v: Cancers [Cancers (Basel)] 2023 Feb 06; Vol. 15 (4). Date of Electronic Publication: 2023 Feb 06.