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Autor:
Nissen, SEE, Lincoff, AM, Brennan, D, Ray, KKK, Mason, D, Kastelein, JJP, Thompson, PDD, Libby, P, Cho, L, Plutzky, J, Bays, HEE, Moriarty, PMM, Menon, V, Grobbee, DEE, Louie, MJJ, Chen, C-F, Li, N, Bloedon, LA, Robinson, P, Horner, M, Sasiela, WJJ, McCluskey, J, Davey, D, Fajardo-Campos, P, Petrovic, P, Fedacko, J, Zmuda, W, Lukyanov, Y, Nicholls, SJJ, CLEAR, OI
Publikováno v:
The New England journal of medicine, 388(15), 1353-1364. Massachussetts Medical Society
BACKGROUND Bempedoic acid, an ATP citrate lyase inhibitor, reduces low-density lipoprotein (LDL) cholesterol levels and is associated with a low incidence of muscle-related adverse events; its effects on cardiovascular outcomes remain uncertain. METH