PI3K/mTOR inhibition induces tumour microenvironment remodelling and sensitises pS6 ^high uterine leiomyosarcoma to PD-1 blockade.

Autor: De Wispelaere W; Department of Oncology, Laboratory of Gynecological Oncology, University of Leuven, Leuven, Belgium.; Department of Human Genetics, Laboratory for Translational Genetics, University of Leuven, Leuven, Belgium.; Laboratory for Translational Genetics, Center for Cancer Biology (CCB), Flemish Institute of Biotechnology (VIB), Leuven, Belgium., Annibali D; Department of Oncology, Laboratory of Gynecological Oncology, University of Leuven, Leuven, Belgium.; Department of Gynecological Oncology, Antoni Van Leeuwenhoek - Netherlands Cancer Institute, Amsterdam, The Netherlands., Tuyaerts S; Department of Medical Oncology, Laboratory of Medical and Molecular Oncology (LMMO), Vrije Universiteit Brussel - UZ Brussel, Brussels, Belgium., Messiaen J; Department of Imaging and Pathology, Translational Cell and Tissue Research, University of Leuven, Leuven, Belgium.; Department of Pediatrics, University Hospitals Leuven, Leuven, Belgium., Antoranz A; Department of Imaging and Pathology, Translational Cell and Tissue Research, University of Leuven, Leuven, Belgium., Shankar G; Department of Imaging and Pathology, Translational Cell and Tissue Research, University of Leuven, Leuven, Belgium., Dubroja N; Department of Imaging and Pathology, Translational Cell and Tissue Research, University of Leuven, Leuven, Belgium., Herreros-Pomares A; Department of Oncology, Laboratory of Gynecological Oncology, University of Leuven, Leuven, Belgium.; Department of Biotechnology, Universitat Politècnica de Valencia, Valencia, Spain., Baiden-Amissah REM; Department of Oncology, Laboratory of Gynecological Oncology, University of Leuven, Leuven, Belgium., Orban MP; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), Flemish Institute of Biotechnology (VIB), Leuven, Belgium.; Department of Oncology, Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), University of Leuven, Leuven, Belgium., Delfini M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), Flemish Institute of Biotechnology (VIB), Leuven, Belgium.; Department of Oncology, Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), University of Leuven, Leuven, Belgium., Berardi E; Department of Development and Regeneration, Laboratory of Tissue Engineering, University of Leuven, Kortrijk, Belgium., Van Brussel T; Department of Human Genetics, Laboratory for Translational Genetics, University of Leuven, Leuven, Belgium.; Laboratory for Translational Genetics, Center for Cancer Biology (CCB), Flemish Institute of Biotechnology (VIB), Leuven, Belgium., Schepers R; Department of Human Genetics, Laboratory for Translational Genetics, University of Leuven, Leuven, Belgium.; Laboratory for Translational Genetics, Center for Cancer Biology (CCB), Flemish Institute of Biotechnology (VIB), Leuven, Belgium., Philips G; Department of Human Genetics, Laboratory for Translational Genetics, University of Leuven, Leuven, Belgium.; Laboratory for Translational Genetics, Center for Cancer Biology (CCB), Flemish Institute of Biotechnology (VIB), Leuven, Belgium., Boeckx B; Department of Human Genetics, Laboratory for Translational Genetics, University of Leuven, Leuven, Belgium.; Laboratory for Translational Genetics, Center for Cancer Biology (CCB), Flemish Institute of Biotechnology (VIB), Leuven, Belgium., Baietti MF; TRACE, Department of Oncology, University of Leuven, Leuven, Belgium., Congedo L; Department of Oncology, Laboratory of Gynecological Oncology, University of Leuven, Leuven, Belgium., HoWangYin KY; TransCure bioServices, Archamps, France., Bayon E; TransCure bioServices, Archamps, France., Van Rompuy AS; Department of Pathology, University Hospitals Leuven, Leuven, Belgium., Leucci E; TRACE, Department of Oncology, University of Leuven, Leuven, Belgium., Tabruyn SP; TransCure bioServices, Archamps, France., Bosisio F; Department of Imaging and Pathology, Translational Cell and Tissue Research, University of Leuven, Leuven, Belgium., Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), Flemish Institute of Biotechnology (VIB), Leuven, Belgium.; Department of Oncology, Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), University of Leuven, Leuven, Belgium., Lambrechts D; Department of Human Genetics, Laboratory for Translational Genetics, University of Leuven, Leuven, Belgium.; Laboratory for Translational Genetics, Center for Cancer Biology (CCB), Flemish Institute of Biotechnology (VIB), Leuven, Belgium., Amant F; Department of Oncology, Laboratory of Gynecological Oncology, University of Leuven, Leuven, Belgium.; Department of Gynecological Oncology, Antoni Van Leeuwenhoek - Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium.

Publikováno v: Clinical and translational medicine [Clin Transl Med] 2024 May; Vol. 14 (5), pp. e1655.

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The Structural Characterization of a Polysaccharide from the Dried Root of Salvia miltiorrhiza and Its Use as a Vaccine Adjuvant to Induce Humoral and Cellular Immune Responses.

Autor: Zhu, Yixuan¹ (AUTHOR) 20221200088@pgs.hebau.edu.cn, Yang, Xiaochen¹ (AUTHOR), Gu, Pengfei¹ (AUTHOR), Wang, Xiao¹ (AUTHOR), Bao, Yongzhan¹ (AUTHOR), Shi, Wanyu¹ (AUTHOR) shiwanyu2010@126.com

Publikováno v: International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 14, p7765. 17p.

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Turn-on detection of Al³⁺ ions using quinoline-based tripodal probe: mechanistic investigation and live cell imaging applications.

Autor: Goswami, Nidhi, Naithani, Sudhanshu, Goswami, Tapas, Kumar, Pankaj, Kumar, Pramod, Kumar, Sushil

Publikováno v: Analytical Methods; 8/7/2024, Vol. 16 Issue 29, p5022-5031, 10p