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Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase.

Autor: Kelly AG; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Wang W; Department of Entomology and Nematology, University of California, Davis, CA 95616.; University of California Davis Comprehensive Cancer Center, Sacramento, CA 95817.; Department of Food Science, Purdue University, West Lafayette, IN 47907., Rothenberger E; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Yang J; Department of Entomology and Nematology, University of California, Davis, CA 95616.; University of California Davis Comprehensive Cancer Center, Sacramento, CA 95817., Gilligan MM; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Kipper FC; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Attaya A; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Gartung A; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Hwang SH; Department of Entomology and Nematology, University of California, Davis, CA 95616.; University of California Davis Comprehensive Cancer Center, Sacramento, CA 95817., Gillespie MJ; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Bayer RL; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Quinlivan KM; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Torres KL; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215., Huang S; Institute of Systems Biology, Seattle, WA 98109., Mitsiades N; University of California Davis Comprehensive Cancer Center, Sacramento, CA 95817.; Department of Internal Medicine, University of California Davis, CA 95817., Yang H; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Food Nutrition and Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China., Hammock BD; Department of Entomology and Nematology, University of California, Davis, CA 95616.; University of California Davis Comprehensive Cancer Center, Sacramento, CA 95817., Panigrahy D; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Feb 13; Vol. 121 (7), pp. e2314085121. Date of Electronic Publication: 2024 Feb 08.

Rho-associated protein kinase 1 inhibition in hepatocytes attenuates nonalcoholic steatohepatitis.

Autor: Dohnalkova E; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.; Department of Biological and Medical Sciences, Charles University, Hradec Kralove, Czech Republic., Bayer RL; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Guo Q; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Bamidele AO; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Kim Lee HS; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Valenzuela-Pérez L; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Krishnan A; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Pavelko KD; Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA., Guisot NES; Redx Pharma Plc, Alderley Park, Macclesfield, UK., Bunyard P; Redx Pharma Plc, Alderley Park, Macclesfield, UK., Kim YB; Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA., Ibrahim SH; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.; Division of Pediatric Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Gores GJ; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Hirsova P; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.

Publikováno v: Hepatology communications [Hepatol Commun] 2023 Jun 02; Vol. 7 (6). Date of Electronic Publication: 2023 Jun 02 (Print Publication: 2023).