Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bayan Mahgoub"'
Autor:
Weikun Xiao, Mahsa Pahlavanneshan, Chae-Young Eun, Xinyu Zhang, Charlene DeKalb, Bayan Mahgoub, Hanaa Knaneh-Monem, Sana Shah, Alireza Sohrabi, Stephanie K. Seidlits, Reginald Hill
Publikováno v:
Matrix Biology Plus, Vol 14, Iss , Pp 100111- (2022)
In pancreatic ductal adenocarcinoma (PDAC), the abundant stromal cells which comprise the tumor microenvironment constitute more than 90% of the primary tumor bulk. Moreover, this desmoplastic environment has been found to be three times stiffer than
Externí odkaz:
https://doaj.org/article/a8af28f560704a41b9f8baf5d777701c
Publikováno v:
Cancer Research. 83:2349-2349
Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate of only 11%. Current treatments that mostly target the cancer cells themselves, have not been able to significantly improve survival rates, meaning there is an urgent need for novel t
Autor:
Yizhan Guo, Thomas H. Barker, Anirban Banerjee, Qing Wang, Amir Manafi, Bayan Mahgoub, Oscar Okwudiri Onyema, Daniel Kreisel, Andrew E. Gelman, Zhongcheng Mei, Mark H. Stoler, Dongge Li, David S. Wilkes, Alexander S. Krupnick
Publikováno v:
American Journal of Transplantation. 19:2705-2718
Despite standardized postoperative care, some lung transplant patients suffer multiple episodes of acute and chronic rejection while others avoid graft problems for reasons that are poorly understood. Using an established model of C57BL/10 to C57BL/6
Autor:
Amir Manafi, Kang Li, Anirban Banerjee, Zhongcheng Mei, Yizhan Guo, Bayan Mahgoub, Alexander S. Krupnick, Lea Paragas, Atsushi Hata, Eric Lazear, Dongge Li, Craig L. Slingluff, Jacqueline S. Slobin, Lei Shi, John Westwick
Publikováno v:
J Immunol
Ex vivo expansion followed by reinfusion of tumor infiltrating leucocytes (TILs) has been utilized successfully for the treatment of multiple malignancies. Most protocols rely on the use of the cytokine interleukin-2 (IL-2) to expand TILs prior to re
Autor:
Bayan Mahgoub, Dongge Li, Andrew E. Gelman, Yizhan Guo, Anirban Banerjee, Adam G. Schrum, Alexander S. Krupnick, Melissa T. Zaidi, Daniel Kreisel, Mark H. Stoler, Amir Manafi, Oscar Okwudiri Onyema, Elizabeth A. Jacobsen, Qing Wang, Zhongcheng Mei
Publikováno v:
JCI Insight. 4
Despite the accepted notion that granulocytes play a universally destructive role in organ and tissue grafts, it has been recently described that eosinophils can facilitate immunosuppression-mediated acceptance of murine lung allografts. The mechanis
Autor:
Bayan Mahgoub, Yizhan Guo, John Westwick, Eric Lazear, Dongge Li, Sarah Hein, Jacqueline Slobin, Lea Paragas, Alexander S. Krupnick, Anirban Banerjee
Publikováno v:
Cancer Research. 80:878-878
A growing arm of adoptive immunotherapy for cancer involves the isolation, expansion and reinfusion of autologous tumor infiltrating leukocytes or TILs. TILs are enriched for tumor-reactive cytotoxic cells that are rendered inactive or anergic by mul
Autor:
Oscar Okwudiri Onyema, Yizhan Guo, Bayan Mahgoub, Amir Manafi, Stacey Criswell, Joanne Lannigan, Elizabeth A Jacobsen, Andrew E Gelman, Daniel Kreisel, Alexander S. Krupnick
Publikováno v:
The Journal of Immunology. 202:69.9-69.9
Eosinophils play a surprising role in downregulating lung graft-specific alloimmunity, even without immunosuppression. We demonstrate here, a mechanism used by eosinophils to downregulate alloimmune responses. To study the mechanism of eosinophil dep