Výsledky vyhledávání - "Bayan A Alhaidhal"

Akademický článek

Identification of echinoderm metabolites as potential inhibitors targeting wild-type and mutant forms of Escherichia coli RNA polymerase (RpoB) for tuberculosis treatment.

Autor: Fatimah M Alsulais, Bayan A Alhaidhal, Ramzi A Mothana, Abdullah R Alanzi

Publikováno v: PLoS ONE, Vol 19, Iss 8, p e0304587 (2024)

Tuberculosis (TB) remains a critical global health challenge, with the emergence of drug-resistant strains heightening concerns. The development of effective drugs targeting both wild-type (WT) and mutant Escherichia coli RNA polymerase β subunit (R

Externí odkaz: https://doaj.org/article/0273326614454762b3185f9882ba513e

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Akademický článek

In silico discovery of druggable targets in Citrobacter koseri using echinoderm metabolites and molecular dynamics simulation

Autor: Bayan A. Alhaidhal, Fatimah M. Alsulais, Ramzi A. Mothana, Abdullah R. Alanzi

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract Citrobacter koseri causes infection in people who are immunocompromised. Without effective antibiotics, these infections can become severe and life-threatening, so effective drugs are essential to treat these infections. Utilizing subtractiv

Externí odkaz: https://doaj.org/article/6f12c089c9d743dd97cdba04bb59fede

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Akademický článek

In silico exploration of potential PRKG1 Inhibitors: A comprehensive study using MTIOPEN Screening, molecular Docking, and MD simulation

Autor: Abdullah R. Alanzi, Bayan Abdullah Alhaidhal, Fatimah Mohammed Alsulais

Publikováno v: Journal of King Saud University: Science, Vol 36, Iss 9, Pp 103372- (2024)

The enzyme protein kinase G1 (PRKG1) plays a crucial role in cellular signaling pathways such as smooth muscle relaxation, neuronal signaling, and platelet aggregation. The dysregulation of PRKG1 leads to different diseases, making it a promising dru

Externí odkaz: https://doaj.org/article/a434a82542fe48c99d130e5a5944aec4

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