Zobrazeno 1 - 10
of 2 318
pro vyhledávání: '"Bay-Jensen, A."'
Autor:
Sofie Falkenløve Madsen, Sarah Spliid Madsen, Alexander Scheller Madrid, Mikkel Rathsach Andersen, Anne-Christine Bay-Jensen, Christian S. Thudium
Publikováno v:
Translational Medicine Communications, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Background We aimed to investigate the development of synovial fibrosis in vitro and how the fibrosis can be halted. Synovial fibrosis causes joint stiffness in arthritic diseases. The pathway of the fibrotic growth factor, transforming grow
Externí odkaz:
https://doaj.org/article/5891c057397349e08699b0e2b5ee9800
Autor:
Solveig Skovlund Groen, Signe Holm Nielsen, Anne Christine Bay-Jensen, Mozhgan Rasti, Darshini Ganatra, Katerina Oikonomopoulou, Vinod Chandran
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-13 (2024)
Abstract Background Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. PsA disease involves flares, which are associated with increased joint inflammation and tissue remodeling. There is a need for identifying biomarker
Externí odkaz:
https://doaj.org/article/41454fbc1ec24023a84d27c66443b726
Autor:
Sofie Falkenløve Madsen, Dovile Sinkeviciute, Christian S. Thudium, Morten A. Karsdal, Anne-Christine Bay-Jensen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Type III collagen gene expression is upregulated in the synovium of patients with rheumatoid arthritis (RA) presenting the fibroid phenotype. The soluble type III collagen formation biomarker, PRO-C3, is known to measure fibrogenesis in fibr
Externí odkaz:
https://doaj.org/article/9dfeba6e89044064af703a8e285e3add
Autor:
Asger Reinstrup Bihlet, Torben Balchen, Kosalaram Goteti, Jesper Sonne, Christoph Ladel, Morten Asser Karsdal, Victor Ona, Flavie Moreau, Roseann Waterhouse, Anne‐Christine Bay‐Jensen, Hans Guehring
Publikováno v:
ACR Open Rheumatology, Vol 6, Iss 4, Pp 205-213 (2024)
Objective To assess the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of single and multiple injections of M6495, a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS‐5) nanobody, in healthy volunteers and patients wi
Externí odkaz:
https://doaj.org/article/59a53152c87d4341ac5e68cc12a2ad20
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Objectives Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation in multiple articular joints, causing pain, joint damage, and loss of joint function. Despite the successful development of disease-modifying
Externí odkaz:
https://doaj.org/article/d632f2e3b3814913af442492e9664f63
Autor:
Marta S. Alexdottir, Martin Pehrsson, Viktor Domislovic, Line E. Godskesen, Aleksander Krag, Jens Kjeldsen, Marko Brinar, Ana Barisic, Anne-Christine Bay-Jensen, Morten A. Karsdal, Zeljko Krznaric, Joachim H. Mortensen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Neutrophils play a significant role in sustaining chronic inflammation in Inflammatory Bowel Disease. The intestinal basement membrane acts as a barrier for immunological homeostasis, where the α3 and α4 chains of type IV collagen are expr
Externí odkaz:
https://doaj.org/article/36ce61ebf75c4f13b829c1c0aa30a870
Autor:
Shirley P. Yu, Leticia A. Deveza, Virginia B. Kraus, Morten Karsdal, Anne-Christine Bay-Jensen, Jamie E. Collins, Ali Guermazi, Frank W. Roemer, Christoph Ladel, Venkatesha Bhagavath, David J. Hunter
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-13 (2024)
Abstract Background To assess the prognostic value of short-term change in biochemical markers as it relates to bone marrow lesions (BMLs) on MRI in knee osteoarthritis (OA) over 24 months and, furthermore, to assess the relationship between biochemi
Externí odkaz:
https://doaj.org/article/66a88f0b88a841a7a733440fa117c61f
Autor:
Solveig Skovlund Groen, Anne-Christine Bay-Jensen, Christian S. Thudium, Morten H. Dziegiel, Marie Skougaard, Simon Francis Thomsen, Signe Holm Nielsen
Publikováno v:
Journal of Translational Autoimmunity, Vol 8, Iss , Pp 100231- (2024)
Introduction: T-helper 17 (Th17) cells produce IL-17A playing a critical role in activating the pathogenic chain leading to joint tissue inflammation and destruction. Elevated levels of Th17 cells and IL-17A have been detected in skin lesions, blood,
Externí odkaz:
https://doaj.org/article/40f6e7b313804048a32321f03f010197
Autor:
Oliver Distler, Britta Maurer, Suzana Jordan, Carina Mihai, Rucsandra Dobrota, Mike Becker, Morten Asser Karsdal, Nicoletta Del Papa, Anne Sofie Siebuhr, Anne-C Bay-Jensen, Pernille Juhl
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Objective Clinical observation suggests that vascular activation and autoimmunity precede remodelling of the extracellular matrix (ECM) in systemic sclerosis (SSc). We challenge this paradigm by hypothesising that ECM biomarkers are already disturbed
Externí odkaz:
https://doaj.org/article/634f22d560e5462fbaa97c1abf5bfba8
Autor:
Cecilie Liv Bager, Joseph P. M. Blair, Man-Hung Eric Tang, Joachim Høg Mortensen, Anne-Christine Bay-Jensen, Peder Frederiksen, Diana Leeming, Claus Christiansen, Morten Asser Karsdal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Citrullinated vimentin has been linked to several chronic and autoimmune diseases, but how citrullinated vimentin is associated with disease prevalence and genetic variants in a clinical setting remains unknown. The aim of this study was to
Externí odkaz:
https://doaj.org/article/c4f6f264d46947fc8cdd368070733f5f