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Astrocytic LRRK2 Controls Synaptic Connectivity via Regulation of ERM Phosphorylation.

Autor: Wang S; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD., Baumert R; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD., Séjourné G; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD., Bindu DS; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.; Department of Neonatology, Children's Mercy Hospital, Kansas City, MO, USA., Dimond K; College of Psychology, Nova Southeastern University, Fort Lauderdale, FL, USA., Sakers K; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.; Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC, USA., Vazquez L; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.; The Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD., Moore J; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.; Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC, USA., Tan CX; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA., Takano T; Division of Molecular Systems for Brain Function, Kyushu University Institute for Advanced Study, Medical Institute of Bioregulation, Japan.; Japan Science and Technology Agency, PRESTO, Japan., Rodriguez MP; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA., Soderling SH; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.; The Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD., La Spada AR; The Department of Neurology, Duke University Medical Center, Durham, NC, USA.; Departments of Pathology & Laboratory Medicine, Neurology, Biological Chemistry, and Neurobiology & Behavior, University of California, Irvine, CA, USA.; UCI Center for Neurotherapeutics, University of California, Irvine, CA, USA., Eroglu C; The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.; The Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD.; Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 28. Date of Electronic Publication: 2024 Aug 28.