Zobrazeno 1 - 10
of 889
pro vyhledávání: '"Baumbach Jan"'
Autor:
Hartung, Michael, Maier, Andreas, Delgado-Chaves, Fernando, Burankova, Yuliya, Isaeva, Olga I., Patroni, Fábio Malta de Sá, He, Daniel, Shannon, Casey, Kaufmann, Katharina, Lohmann, Jens, Savchik, Alexey, Hartebrodt, Anne, Chervontseva, Zoe, Firoozbakht, Farzaneh, Probul, Niklas, Zotova, Evgenia, Tsoy, Olga, Blumenthal, David B., Ester, Martin, Laske, Tanja, Baumbach, Jan, Zolotareva, Olga
Most complex diseases, including cancer and non-malignant diseases like asthma, have distinct molecular subtypes that require distinct clinical approaches. However, existing computational patient stratification methods have been benchmarked almost ex
Externí odkaz:
http://arxiv.org/abs/2408.00200
Autor:
Burankova, Yuliya, Abele, Miriam, Bakhtiari, Mohammad, von Törne, Christine, Barth, Teresa, Schweizer, Lisa, Giesbertz, Pieter, Schmidt, Johannes R., Kalkhof, Stefan, Müller-Deile, Janina, van Veelen, Peter A, Mohammed, Yassene, Hammer, Elke, Arend, Lis, Adamowicz, Klaudia, Laske, Tanja, Hartebrodt, Anne, Frisch, Tobias, Meng, Chen, Matschinske, Julian, Späth, Julian, Röttger, Richard, Schwämmle, Veit, Hauck, Stefanie M., Lichtenthaler, Stefan, Imhof, Axel, Mann, Matthias, Ludwig, Christina, Kuster, Bernhard, Baumbach, Jan, Zolotareva, Olga
Quantitative mass spectrometry has revolutionized proteomics by enabling simultaneous quantification of thousands of proteins. Pooling patient-derived data from multiple institutions enhances statistical power but raises significant privacy concerns.
Externí odkaz:
http://arxiv.org/abs/2407.15220
Autor:
Wolff Justus, Matschinske Julian, Baumgart Dietrich, Pytlik Anne, Keck Andreas, Natarajan Arunakiry, von Schacky Claudio E., Pauling Josch K., Baumbach Jan
Publikováno v:
Journal of Integrative Bioinformatics, Vol 19, Iss 4, Pp 594971-15 (2022)
The implementation of Artificial Intelligence (AI) still faces significant hurdles and one key factor is the access to data. One approach that could support that is federated machine learning (FL) since it allows for privacy preserving data access. F
Externí odkaz:
https://doaj.org/article/467544b883d34323b8b9022976b18374
Autor:
Barbosa Eudes, Röttger Richard, Hauschild Anne-Christin, de Castro Soares Siomar, Böcker Sebastian, Azevedo Vasco, Baumbach Jan
Publikováno v:
Journal of Integrative Bioinformatics, Vol 14, Iss 2, Pp 1366-1372 (2017)
Distinct bacteria are able to cope with highly diverse lifestyles; for instance, they can be free living or host-associated. Thus, these organisms must possess a large and varied genomic arsenal to withstand different environmental conditions. To fac
Externí odkaz:
https://doaj.org/article/3b1e2c33bcd7496a925afaa042134663
Autor:
Larsen Simon J., Baumbach Jan
Publikováno v:
Journal of Integrative Bioinformatics, Vol 14, Iss 2, Pp 631-44 (2017)
Comparative analysis of biological networks is a major problem in computational integrative systems biology. By computing the maximum common edge subgraph between a set of networks, one is able to detect conserved substructures between them and quant
Externí odkaz:
https://doaj.org/article/cceb13f7ddb346b6b60d49abb67e2a6d
Autor:
Almeida Diogo, Skov Ida, Lund Jesper, Mohammadnejad Afsaneh, Silva Artur, Vandin Fabio, Tan Qihua, Baumbach Jan, Röttger Richard
Publikováno v:
Journal of Integrative Bioinformatics, Vol 13, Iss 4, Pp 24-32 (2016)
Measuring differential methylation of the DNA is the nowadays most common approach to linking epigenetic modifications to diseases (called epigenome-wide association studies, EWAS). For its low cost, its efficiency and easy handling, the Illumina Hum
Externí odkaz:
https://doaj.org/article/099aef4d079141dda40083ac85e19752
Publikováno v:
Journal of Integrative Bioinformatics, Vol 13, Iss 1, Pp 1-6 (2016)
Systems biology plays a central role for biological network analysis in the post-genomic era. Cytoscape is the standard bioinformatics tool offering the community an extensible platform for computational analysis of the emerging cellular network toge
Externí odkaz:
https://doaj.org/article/c67ebac135be452d90ad04150e2bb988
Publikováno v:
Journal of Integrative Bioinformatics, Vol 12, Iss 3, Pp 16-25 (2015)
Electronic laboratory notebooks (ELNs) are more accessible and reliable than their paper based alternatives and thus find widespread adoption. While a large number of commercial products is available, small- to mid-sized laboratories can often not af
Externí odkaz:
https://doaj.org/article/1ed26e4bae124f15b3e0e2b437987e06
Autor:
Maier, Andreas, Hartung, Michael, Abovsky, Mark, Adamowicz, Klaudia, Bader, Gary D., Baier, Sylvie, Blumenthal, David B., Chen, Jing, Elkjaer, Maria L., Garcia-Hernandez, Carlos, Helmy, Mohamed, Hoffmann, Markus, Jurisica, Igor, Kotlyar, Max, Lazareva, Olga, Levi, Hagai, List, Markus, Lobentanzer, Sebastian, Loscalzo, Joseph, Malod-Dognin, Noel, Manz, Quirin, Matschinske, Julian, Mee, Miles, Oubounyt, Mhaned, Pico, Alexander R., Pillich, Rudolf T., Poschenrieder, Julian M., Pratt, Dexter, Pržulj, Nataša, Sadegh, Sepideh, Saez-Rodriguez, Julio, Sarkar, Suryadipto, Shaked, Gideon, Shamir, Ron, Trummer, Nico, Turhan, Ugur, Wang, Ruisheng, Zolotareva, Olga, Baumbach, Jan
In recent decades, the development of new drugs has become increasingly expensive and inefficient, and the molecular mechanisms of most pharmaceuticals remain poorly understood. In response, computational systems and network medicine tools have emerg
Externí odkaz:
http://arxiv.org/abs/2305.15453
Autor:
Lobentanzer, Sebastian, Feng, Shaohong, Consortium, The BioChatter, Maier, Andreas, Wang, Cankun, Baumbach, Jan, Krehl, Nils, Ma, Qin, Saez-Rodriguez, Julio
Current-generation Large Language Models (LLMs) have stirred enormous interest in recent months, yielding great potential for accessibility and automation, while simultaneously posing significant challenges and risk of misuse. To facilitate interfaci
Externí odkaz:
http://arxiv.org/abs/2305.06488