The shikimate pathway: gateway to metabolic diversity.

Autor: Shende VV; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, 92093, USA. bsmoore@ucsd.edu., Bauman KD; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Moore BS; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, 92093, USA. bsmoore@ucsd.edu.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, 92093, USA.

Publikováno v: Natural product reports [Nat Prod Rep] 2024 Apr 24; Vol. 41 (4), pp. 604-648. Date of Electronic Publication: 2024 Apr 24.

Enzymatic assembly of the salinosporamide γ-lactam-β-lactone anticancer warhead.

Autor: Bauman KD; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Shende VV; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Chen PY; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.; Morphic Therapeutics, Waltham, MA, USA., Trivella DBB; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.; Brazilian Biosciences National Laboratory, National Center for Research in Energy and Materials, Campinas, Brazil.; Institute of Chemistry, University of Campinas, Campinas, Brazil., Gulder TAM; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.; Chair of Technical Biochemistry, Technical University of Dresden, Dresden, Germany., Vellalath S; Department of Chemistry and Biochemistry, Baylor University, Waco, TX, USA., Romo D; Department of Chemistry and Biochemistry, Baylor University, Waco, TX, USA., Moore BS; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA. bsmoore@ucsd.edu.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA. bsmoore@ucsd.edu.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2022 May; Vol. 18 (5), pp. 538-546. Date of Electronic Publication: 2022 Mar 21.

A community resource for paired genomic and metabolomic data mining.

Autor: Schorn MA; Laboratory of Microbiology, Department of Agricultural and Food Sciences, Wageningen University, Wageningen, the Netherlands.; Bioinformatics Group, Wageningen University, Wageningen, the Netherlands., Verhoeven S; Netherlands eScience Center, Amsterdam, the Netherlands., Ridder L; Netherlands eScience Center, Amsterdam, the Netherlands., Huber F; Netherlands eScience Center, Amsterdam, the Netherlands., Acharya DD; Wisconsin Institute for Discovery and Department of Plant Pathology, University of Wisconsin-Madison, Madison, WI, USA., Aksenov AA; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Aleti G; Department of Psychiatry, University of California San Diego, San Diego, CA, USA., Moghaddam JA; Leibniz Institute for Natural Product Research and Infection Biology e.V. Hans-Knöll-Institute (HKI), Jena, Germany., Aron AT; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Aziz S; Pharmaceutical Biology Department, Pharmaceutical Institute, Eberhard Karls University Tübingen, Tübingen, Germany.; Microbiology Department, Biology Faculty, Jenderal Soedirman University, Purwokerto, Indonesia., Bauermeister A; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.; Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Bauman KD; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Baunach M; University of Potsdam, Institute of Biochemistry and Biology, Potsdam-Golm, Germany., Beemelmanns C; Leibniz Institute for Natural Product Research and Infection Biology e.V. Hans-Knöll-Institute (HKI), Jena, Germany., Beman JM; Department of Life and Environmental Sciences, University of California Merced, Merced, CA, USA.; Sierra Nevada Research Institute, University of California Merced, Merced, CA, USA., Berlanga-Clavero MV; Instituto de Hortofruticultura Subtropical y Mediterránea 'La Mayora', Universidad de Málaga-Consejo Superior de Investigaciones Científicas, Departamento de Microbiología, Universidad de Málaga, Málaga, Spain., Blacutt AA; Department of Microbiology and Plant Pathology, University of California Riverside, Riverside, CA, USA., Bode HB; Molecular Biotechnology, Department of Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany.; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.; Senckenberg Gesellschaft für Naturforschung, Frankfurt am Main, Germany.; Max-Planck-Institute for Terrestrial Microbiology, Department of Natural Products in Organismic Interactions, Marburg, Germany., Boullie A; Institut Pasteur, Collection of Cyanobacteria, Paris, France., Brejnrod A; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Bugni TS; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Calteau A; Laboratoire d'Analyses Bioinformatiques pour la Génomique et le Métabolisme, Génomique Métabolique, Genoscope, Institut François Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, Evry, France., Cao L; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA., Carrión VJ; Microbial Biotechnology, Institute of Biology, Leiden University, Leiden, the Netherlands.; Department of Microbial Ecology, Netherlands Institute of Ecology, Wageningen, the Netherlands., Castelo-Branco R; Interdisciplinary Centre of Marine and Environmental Research), University of Porto, Porto, Portugal.; Faculty of Sciences, University of Porto, Porto, Portugal.; Department of Microbiology, University of Helsinki, Helsinki, Finland., Chanana S; Wisconsin Institute for Discovery and Department of Plant Pathology, University of Wisconsin-Madison, Madison, WI, USA., Chase AB; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Chevrette MG; Wisconsin Institute for Discovery and Department of Plant Pathology, University of Wisconsin-Madison, Madison, WI, USA., Costa-Lotufo LV; Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Crawford JM; Department of Chemistry, Yale University, New Haven, CT, USA.; Chemical Biology Institute, Yale University, West Haven, CT, USA.; Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT, USA., Currie CR; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.; Department of Energy Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, University of Wisconsin-Madison, Madison, WI, USA., Cuypers B; Adrem Data Lab, Department of Computer Science, University of Antwerp, Antwerp, Belgium.; Molecular Parasitology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium., Dang T; Technische Universität Berlin, Institut für Chemie, Berlin, Germany., de Rond T; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Demko AM; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Dittmann E; University of Potsdam, Institute of Biochemistry and Biology, Potsdam-Golm, Germany., Du C; Microbial Biotechnology, Institute of Biology, Leiden University, Leiden, the Netherlands., Drozd C; Department of Microbiology and Plant Pathology, University of California Riverside, Riverside, CA, USA., Dujardin JC; Molecular Parasitology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium., Dutton RJ; Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA.; Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA., Edlund A; J. Craig Venter Institute, Genomic Medicine Group, La Jolla, CA, USA.; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, USA., Fewer DP; Department of Microbiology, University of Helsinki, Helsinki, Finland., Garg N; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA., Gauglitz JM; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Gentry EC; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Gerwick L; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Glukhov E; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Gross H; Pharmaceutical Biology Department, Pharmaceutical Institute, Eberhard Karls University Tübingen, Tübingen, Germany., Gugger M; Institut Pasteur, Collection of Cyanobacteria, Paris, France., Guillén Matus DG; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Helfrich EJN; Molecular Biotechnology, Department of Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany.; Senckenberg Gesellschaft für Naturforschung, Frankfurt am Main, Germany.; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard University, Boston, MA, USA., Hempel BF; Technische Universität Berlin, Institut für Chemie, Berlin, Germany.; Charité, University Medicine Berlin, Berlin-Brandenburg Center for Regenerative Therapy (BCRT), Campus Virchow Klinikum, Berlin, Germany., Hur JS; Korean Lichen Research Institute, Sunchon National University, Sunchon, Republic of Korea., Iorio M; Naicons Srl, Milano, Italy., Jensen PR; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Kang KB; College of Pharmacy, Sookmyung Women's University, Seoul, Korea., Kaysser L; Pharmaceutical Biology Department, Pharmaceutical Institute, Eberhard Karls University Tübingen, Tübingen, Germany.; German Centre for Infection Research (DZIF), Tübingen, Germany., Kelleher NL; Department of Chemistry, Northwestern University, Evanston, IL, USA., Kim CS; Department of Chemistry, Yale University, New Haven, CT, USA.; Chemical Biology Institute, Yale University, West Haven, CT, USA.; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea., Kim KH; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea., Koester I; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., König GM; Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany., Leao T; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Lee SR; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.; Department of Chemistry, Princeton University, Princeton, NJ, USA., Lee YY; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA., Li X; Section of Microbiology, University of Copenhagen, Copenhagen, Denmark., Little JC; Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL, USA., Maloney KN; Department of Chemistry, Point Loma Nazarene University, San Diego, CA, USA., Männle D; Pharmaceutical Biology Department, Pharmaceutical Institute, Eberhard Karls University Tübingen, Tübingen, Germany.; German Centre for Infection Research (DZIF), Tübingen, Germany.; Interfaculty Institute for Microbiology and Infection Medicine Tübingen, Microbiology and Biotechnology, University of Tübingen, Tübingen, Germany., Martin H C; Centro de Biodiversidad y Descubrimiento de Drogas, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología, Panama, Republic of Panama., McAvoy AC; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA., Metcalf WW; Carl R. Woese Institute for Genomic Biology and Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Mohimani H; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA., Molina-Santiago C; Instituto de Hortofruticultura Subtropical y Mediterránea 'La Mayora', Universidad de Málaga-Consejo Superior de Investigaciones Científicas, Departamento de Microbiología, Universidad de Málaga, Málaga, Spain., Moore BS; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.; Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Mullowney MW; Department of Chemistry, Northwestern University, Evanston, IL, USA., Muskat M; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Nothias LF; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., O'Neill EC; School of Chemistry, University of Nottingham, Nottingham, UK., Parkinson EI; Department of Chemistry and Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA., Petras D; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Piel J; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland., Pierce EC; Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA., Pires K; Instituto Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil., Reher R; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Romero D; Instituto de Hortofruticultura Subtropical y Mediterránea 'La Mayora', Universidad de Málaga-Consejo Superior de Investigaciones Científicas, Departamento de Microbiología, Universidad de Málaga, Málaga, Spain., Roper MC; Department of Microbiology and Plant Pathology, University of California Riverside, Riverside, CA, USA., Rust M; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland., Saad H; Pharmaceutical Biology Department, Pharmaceutical Institute, Eberhard Karls University Tübingen, Tübingen, Germany.; Phytochemistry and Plant Systematics Department, Division of Pharmaceutical Industries, National Research Centre, Cairo, Egypt., Saenz C; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sanchez LM; Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL, USA., Sørensen SJ; Section of Microbiology, University of Copenhagen, Copenhagen, Denmark., Sosio M; Naicons Srl, Milano, Italy., Süssmuth RD; Technische Universität Berlin, Institut für Chemie, Berlin, Germany., Sweeney D; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Tahlan K; Department of Biology, Memorial University of Newfoundland, St. John's, Canada., Thomson RJ; Department of Chemistry, Northwestern University, Evanston, IL, USA., Tobias NJ; Senckenberg Gesellschaft für Naturforschung, Frankfurt am Main, Germany.; LOEWE-Centre for Translational Biodiversity Genomics, Frankfurt am Main, Germany., Trindade-Silva AE; Departamento de Fisiologia e Farmacologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Ceará, Brazil., van Wezel GP; Microbial Biotechnology, Institute of Biology, Leiden University, Leiden, the Netherlands., Wang M; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Weldon KC; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.; Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA., Zhang F; Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA., Ziemert N; German Centre for Infection Research (DZIF), Tübingen, Germany.; Interfaculty Institute for Microbiology and Infection Medicine Tübingen, Microbiology and Biotechnology, University of Tübingen, Tübingen, Germany., Duncan KR; University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Sciences, Glasgow, UK., Crüsemann M; Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany., Rogers S; School of Computing Science, University of Glasgow, Glasgow, UK., Dorrestein PC; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA. pdorrestein@health.ucsd.edu.; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA. pdorrestein@health.ucsd.edu.; Center for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA. pdorrestein@health.ucsd.edu.; Department of Pharmacology and Pediatrics, University of California San Diego, La Jolla, CA, USA. pdorrestein@health.ucsd.edu., Medema MH; Bioinformatics Group, Wageningen University, Wageningen, the Netherlands. marnix.medema@wur.nl., van der Hooft JJJ; Bioinformatics Group, Wageningen University, Wageningen, the Netherlands. justin.vanderhooft@wur.nl.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2021 Apr; Vol. 17 (4), pp. 363-368.

Maternal transfer and sublethal immune system effects of brevetoxin exposure in nesting loggerhead sea turtles (Caretta caretta) from western Florida.

Autor: Perrault JR; Marine Immunology Program, Mote Marine Laboratory, 1600 Ken Thompson Parkway, Sarasota, FL 34236, USA. Electronic address: jperrault@usfsp.edu., Bauman KD; Department of Chemistry and Biochemistry, Middlebury College, 14 Old Chapel Road, Middlebury, VT 05753, USA. Electronic address: kbauman@ucsd.edu., Greenan TM; College of Arts and Sciences, University of South Florida Sarasota-Manatee, 8350 North Tamiami Trail, Sarasota, FL 34243, USA. Electronic address: taylorgreenan@gmail.com., Blum PC; Marine Immunology Program, Mote Marine Laboratory, 1600 Ken Thompson Parkway, Sarasota, FL 34236, USA. Electronic address: pcblum@mote.org., Henry MS; Marine Immunology Program, Mote Marine Laboratory, 1600 Ken Thompson Parkway, Sarasota, FL 34236, USA. Electronic address: mhenry@mote.org., Walsh CJ; Marine Immunology Program, Mote Marine Laboratory, 1600 Ken Thompson Parkway, Sarasota, FL 34236, USA. Electronic address: cjwalsh@mote.org.

Publikováno v: Aquatic toxicology (Amsterdam, Netherlands) [Aquat Toxicol] 2016 Nov; Vol. 180, pp. 131-140. Date of Electronic Publication: 2016 Oct 01.